1 results match your criteria: "Sr. Alzheimer's Center and Research Institute Tampa[Affiliation]"
The utility of age-specific cut-offs for visual rating of medial temporal atrophy in classifying Alzheimer's disease, MCI and cognitively normal elderly subjects.
Front Aging Neurosci
October 2013
Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center Miami Beach, FL, USA ; Departments of Medicine and Neurology, Miller School of Medicine, University of Miami Miami, FL, USA ; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami Miami, USA ; Department of Neurology, Florida International University College of Medicine Miami, FL, USA ; Departments of Molecular Medicine and Neurology, University of South Florida Tampa, FL, USA ; Johnnie B. Byrd, Sr. Alzheimer's Center and Research Institute Tampa, FL, USA.
Background: New research criteria for diagnosing Alzheimer's disease (AD) in the mild cognitive impairment stage (MCI-AD) incorporate biomarkers to assign a level of certainty to the diagnosis. Structural MRI is widely available but greatly under-utilized for assessing atrophy of structures affected in early AD, such as the hippocampus (HP), because the quantification of HP volumes (HP-v) requires special expertise, and normative values have not been established.
Methods: Elderly subjects (n =273) from the Florida ADRC were classified as having no cognitive impairment (cognitively normal, CN), amnestic mild cognitive impairment (aMCI) or AD.