1 results match your criteria: "Spitalul Clinic Judetean de Urgenta Sibiu[Affiliation]"

From a Better Understanding of the Mechanisms of Action of Histone Deacetylases Inhibitors to the Progress of the Treatment of Malignant Lymphomas and Plasma Cell Myeloma.

Recent Pat Anticancer Drug Discov

November 2017

"Lucian Blaga" University of Sibiu, Faculty of Medicine, Spitalul Clinic Judetean de Urgenta Sibiu, str Lucian Blaga, nr 2A, Sibiu, 550169 Sibiu, Romania.

Background: Notable progress has been made in chemo- and immunotherapy of B-cell lymphomas, but less in the treatment of T-cell lymphomas.

Objective: Histone deacetylases inhibitors are a potentially useful therapeutic mean, as an epigenetic dysregulation is present in lymphomas, and especially in T-cell types. We aimed to study the progress made in this area.

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