82 results match your criteria: "Spinal Cord Tumors - Management of Intradural Intramedullary Neoplasms"
Clin Neurol Neurosurg
November 2024
Department of Neurosurgery, Shanghai Institute of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, PR China. Electronic address:
Curr Oncol
July 2024
Department of Neurosurgery, University Hospital, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.
Objective: Intradural spinal metastases are considered rare. At present, limited information is available on incidence, surgical management, and outcomes.
Methods: We conducted a retrospective patient chart review from 2002 to 2024, identifying all patients surgically treated for intradural spinal metastases.
World Neurosurg
May 2024
Department of Neurologic Surgery, Neuro-Informatics Laboratory, Mayo Clinic, Rochester, Minnesota, USA; Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:
Background: Capillary hemangiomas are rare vascular lesions that rarely affect the central nervous system. When they present within the spinal canal, they are typically confined intradurally, with intramedullary extension rare. We present a rare case of spinal intramedullary capillary hemangioma, with a systematic review of the literature.
View Article and Find Full Text PDFObjective: This article discusses the diagnostic approach to patients with suspected neoplasms of the spinal cord and reviews the most common primary and metastatic spinal neoplasms and their presentations.
Latest Developments: Neoplasms of the spinal cord are rare entities that can involve the spinal cord parenchyma, the dura and leptomeninges, or the extradural space. The most common intramedullary spinal cord neoplasms are primary spinal cord tumors, including ependymomas, pilocytic astrocytomas, and diffuse midline gliomas.
World Neurosurg
April 2024
Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, Arizona, USA.
Primary spinal cord tumors are relatively rare, comprising approximately 4%-16% of all tumors originating from the central nervous system. These tumors are anatomically separable into 2 broad categories: intradural intramedullary and intradural extramedullary. Intramedullary tumors are composed predominantly of gliomas (infiltrative astrocytoma) and ependymomas.
View Article and Find Full Text PDFJ Orthop Sci
September 2024
Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; Niigata Spine Surgery Center, Kameda Daiichi Hospital, Niigata, Japan. Electronic address:
Background: Intraoperative pathological diagnosis has a major influence on the intra- and postoperative management of spinal cord tumors. Thus, the aim of this study was to assess the reliability of intraoperative pathological diagnosis for spinal cord lesions by comparing it with the final pathological diagnosis and to determine its usefulness and limitations.
Method: Three-hundred and three consecutive patients (mean age, 53.
Cureus
August 2023
Internal Medicine, Des Moines University, Des Moines, USA.
Primary spinal cord glioblastoma multiforme (GBM) remains uncommon and typically affects males and patients during their fifth decade of life. Our case demonstrates a 77-year-old woman who initially presented with right arm paresthesia and limited range of motion and was subsequently diagnosed with primary spinal cord GBM. Our case illustrates an atypical and nonspecific neurological presentation highlighting that spinal cord GBM can have a more indolent course, unlike what current literature suggests.
View Article and Find Full Text PDFPediatr Neurosurg
November 2023
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Background: Spinal tumors are rare pathology in the pediatric population. The tumors can be classified as extradural, intradural extramedullary, or intramedullary. Any of the spinal tumors can eventually lead to spinal deformity.
View Article and Find Full Text PDFNeurochirurgie
September 2023
Department of pediatric neurosurgery, University of Lille, Lille University Hospital, Lille, France.
Background And Purpose: Non-dysraphic intramedullary spinal cord lipomas (NDSCL) represent 1% of spinal cord tumors. They are less frequent than dysraphic spinal cord lipomas and clinical presentation is unspecific. There are no guidelines on surgical management.
View Article and Find Full Text PDFAdv Exp Med Biol
July 2023
Institute for Brain Protections Sciences, Johns Hopkins All Children's Hospital, Saint Petersburg, FL, USA.
Benign spinal intradural tumors are relatively rare and include intramedullary tumors with a favorable histology such as low-grade astrocytomas and ependymomas, as well as intradural extramedullary tumors such as meningiomas and schwannomas. The effect on the neural tissue is usually a combination of mass effect and neuronal involvement in cases of infiltrative tumors. The new understanding of molecular profiling of different tumors allowed us to better define central nervous system tumors and tailor treatment accordingly.
View Article and Find Full Text PDFAdv Exp Med Biol
July 2023
Institute for Brain Protections Sciences, Johns Hopkins All Children's Hospital, Saint Petersburg, FL, USA.
Malignant spinal tumors constitute around 22% of all primary spinal tumors. The most common location of metastases to the spinal region is the extradural compartment. The molecular and genetic characterization of these tumors was the basis for the updated WHO classification of CNS tumors in 2016, where many CNS tumors are now diagnosed according to their genetic profile rather than relying solely on the histopathological appearance.
View Article and Find Full Text PDFPediatr Neurosurg
November 2023
Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Background: Incidental intradural tumors of the spine in the pediatric population are rare lesions whose management remains unclear. Surgeons must balance the risks of iatrogenic deficits and complications after surgical resection against the risks from progressive growth of the tumor. Moreover, the natural history of an incidental finding can be difficult to predict.
View Article and Find Full Text PDFWorld Neurosurg
June 2023
Neurosurgical Unit, Department of Biomedicine, Neurosciences and Advanced Diagnostics (BiND), University of Palermo, Palermo, Italy.
Spine J
July 2023
Department of Neurological Surgery, The GW School of Medicine & Health Sciences, 2150 Pennsylvania Ave, NW, Suite 7-420, Washington, DC 20037, USA.
Background Content: Diffuse gliomas of the spine (DGS)-consisting of intradural intramedullary glioblastoma, astrocytoma, and oligodendroglioma-are exceedingly rare tumors that account for about 2% of primary spinal cord tumors. Much is unknown about their optimal treatment regimen due to a relative lack of clinical outcome data.
Purpose: To provide an updated analysis on treatment and outcomes in DGS.
Background: Spinal tumors constitute 10-32% of all primary central nervous system tumors. Accurate radiologic and histopathology diagnosis is crucial in the management and prognosis. The aim of the study was to describe the imaging patterns and to determine the agreement of imaging pattern of spinal tumors with intra-operative and histopathology findings.
View Article and Find Full Text PDFActa Neurochir (Wien)
September 2022
Department of Neurosurgery, King's College Hospital NHS Foundation Trust, Denmark Hill, London, SE5 9RS, UK.
We describe the first ever-reported occurrence of a post-operative tension pneumosyrinx occurring after a resection of an intradural intramedullary spinal tumour in a 40-year-old patient. Post-operatively, he developed sudden onset paraplegia and imaging revealed a tension pneumosyrinx which was subsequently surgically decompressed. He made a gradual neurological recovery.
View Article and Find Full Text PDFWorld Neurosurg
July 2022
Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah, USA. Electronic address:
Although rare, intramedullary spinal cavernous malformations have a 1.4%-6.8% annual hemorrhage risk and can cause significant morbidity.
View Article and Find Full Text PDFNeurochirurgie
July 2022
Service de neurochirurgie, hôpital Roger-Salengro, CHU de Lille, Lille, France; Université de Lille, Lille, France.
Background: Some authors used minimally invasive surgery (MIS) in the treatment of spinal cord tumor, but these studies had a small sample sizes and mixed extra- and intra-medullary tumors, resulting in confounding biases. The objectives of the present study were to evaluate the effectiveness and safety of MIS for spinal meningioma resection in comparison with open surgery (OS).
Methods: Consecutive patients with spinal meningioma who received either MIS or OS were included.
Surg Neurol Int
August 2021
Department of Neurosurgery, Hospital Municipal Miguel Couto, Rio de Janeiro, Brazil.
Background: Ependymoma is a slowly growing benign neoplasm that constitutes 3-9% of all neuroepithelial spinal cord tumors.[3,4] They rarely involve the cervicomedullary junction where they both compress the distal brainstem and upper cervical cord. Due to the critical contiguous structures, gross total resection of these lesions may result in significant morbidity/mortality.
View Article and Find Full Text PDFBr J Neurosurg
December 2023
Department of Neurosurgery, All India Institute of Medical Sciences, Bhopal, India.
Introduction: Intradural spinal lipomas are very rare and constitute less than 1% of all spinal tumors. Such tumors are usually associated with spinal dysraphism and occur mostly in the lumbosacral or cervical region. Intradural spinal lipomas tends to be intramedullary or subpial.
View Article and Find Full Text PDFWorld Neurosurg
August 2021
Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, USA; Section of Neurological Surgery, Surgery Service Line, Edward Hines, Jr. VA Hospital, Hines, Illinois, USA. Electronic address:
Background: Hemangioblastomas are benign vascular neoplasms of the central nervous system that may occur sporadically or in association with Von Hippel-Lindau disease. A minority of these lesions can occur in the spine, mostly as intramedullary masses. The authors present a rare case of primary sporadic spinal hemangioblastoma occurring as an intradural extramedullary (IDEM) lesion.
View Article and Find Full Text PDFBackground: Hemangioblastomas are rare, slow-growing, and highly vascularized tumors that typically occur in the cerebellum and spinal cord. The cervical and thoracic regions are the most common spinal sites, and the tumors are usually intramedullary.
Observations: The authors report the case of a man whose chest computed tomography performed for managing coronavirus disease 2019 incidentally revealed an enhancing area in the spinal canal at T12-L1.
Spinal Cord Ser Cases
January 2021
Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan.
Introduction: Of the 23 cases of spinal intradural-extramedullary ependymomas which have been reported to date, 11 were diagnosed as anaplastic. Here we present a very rare case of a thoracic intradural-extramedullary (not intramedullary) anaplastic ependymoma in an adult along with a literature review.
Case Presentation: A 29-year-old man presented with rapidly progressive gait disturbance, a sensory-deficit below the trunk and urination disorders that had begun a few months earlier.
J Neurosurg Case Lessons
January 2021
Department of Neurosurgery, Mayo Clinic Arizona, Phoenix, Arizona; and.
Background: Intramedullary spinal cord tumors represent a minority of intradural tumors. Among intramedullary spinal cord tumors, hemangioblastomas are uncommon, and schwannomas are extremely rare. Collision tumors are histologically distinct tumors that are intermingled and growing together.
View Article and Find Full Text PDFFront Oncol
June 2020
Departments of Radiation Oncology, NYU Grossman School of Medicine, New York, NY, United States.
Stereotactic radiation treatment can be used to treat spinal cord neoplasms in patients with either unresectable lesions or residual disease after surgical resection. While treatment guidelines have been suggested for epidural lesions, the utility of stereotactic radiation for intradural and intramedullary malignancies is still debated. Prior reports have suggested that stereotactic radiation approaches can be used for effective tumor control and symptom management.
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