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Targeted therapy for pediatric low-grade glioma.

Childs Nerv Syst

August 2021

Pediatric Hematology and Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.

Purpose: Pediatric low-grade gliomas are the most frequent brain tumors in children. The standard approach for symptomatic unresectable tumors is chemotherapy. Recently, key molecular alterations/pathways have been identified and targeted drugs developed and tested in clinical trials.

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