Early Improvement in Cardiac Function and Dyssynchrony After Physiological Upgrading in Pacing-Induced Cardiomyopathy.

Background: Interventricular dyssynchrony derived from the classic non-physiological stimulation (n-PS) of the right ventricle (RV) is a known cause of left ventricular dysfunction (LVDys).

Methods: This was a prospective descriptive single-center study. We analyzed patients who develop LVDys with n-PS, and the results after upgrading to conduction system pacing (CSP).

A Comparison between the Methodology of the Mainstream in (Neuro-)Psychology, Holzkamp's and Vygotsky's Approach.

The present paper treats the issue of methodological assumptions in mainstream neuropsychology and, as counter-concepts, in Vygotsky's approach and Holzkamp's critical psychology. The analysis identifies four main assumptions concerning the methodology of mainstream neuropsychology, which are contrasted with the positions of other approaches. The methodologies of the mainstream neuropsychology vs.

Diagnostic value of hemoglobin concentration in identifying Meckel's diverticulum in pediatric lower gastrointestinal bleeding.

Purpose: To assess the diagnostic performance of hemoglobin concentration for Meckel's diverticulum (MD) and evaluate if hemoglobin levels could be useful in the surgical decision-making process of children with lower gastrointestinal bleeding (LGIB).

Methods: Retrospective cohort study of children with LGIB attending the emergency department between 2011 and 2021. Episodes of LGIB were divided into two groups: MeckD (MD diagnosed by surgery) and non-MeckD.

Real-world experience of diagnosis, disability, and daily management in parents of children with different genetic developmental and epileptic encephalopathies: a qualitative study.

Purpose: This study describes the experience of parents of children with developmental and epileptic encephalopathies (DEE) and how the disease impacts their daily lives.

Materials And Methods: A descriptive qualitative study was conducted using purposeful sampling. Twenty-one parents of children with DEEs caused by SCN1A, KCNQ2, CDKL5, PCDH19, and GNAO1 variants were included.

An Atlas of Anatomical Variants of the Human Talus.

Anatomical variants can be used effectively to identify relationships between individuals in kinship analysis and they may be useful during surgical procedures. These procedures can be better implemented when the cause, appearance and location are understood. Clear representations and definitions of anatomical traits are necessary.

Outliers of Treatment Frequency in Retinal Vein Occlusion: 24-Month Comparative Analysis of Fight Retinal Blindness! Practitioners.

Background: We aimed to describe a 2-year outcome of eyes managed by practitioners benchmarked using a funnel plot by their frequency of treatment using vascular endothelial growth factor (VEGF) inhibitors for naive retinal vein occlusion (RVO).

Methods: A multicentre, international, observational study of 29 doctors in 12 countries managing 1110 eyes with RVO commencing VEGF inhibitors between 1 January 2012-2022 tracked in the Fight Retinal Blindness! registry.

Results: We identified 3 outlying 'intensive' practitioners (managing 350/1110 eyes [32%]), 22 'typical' practitioners (604/1110, [54%]) and 4 outlying 'relaxed' practitioners (156/1110, [14%]) with respective 24-month outcomes in Branch and Central RVO including the primary outcome, mean adjusted change in visual acuity (VA) in BRVO: +16.

Black soldier fly larvae: a one health approach to investigate gut, and organ health and meat quality response in slow-growing chickens.

Background: The inclusion of sustainable protein sources in poultry feed has become essential for improving animal welfare in livestock production. Black soldier fly larvae are a promising solution due to their high protein content and sustainable production. However, most research has focused on fast-growing poultry breeds, while the effects on native breeds, such as the Bianca di Saluzzo, are less explored.

Patient satisfaction and safety in the administration of sedation by nursing staff in the digestive endoscopy service: a cross-sectional study.

Background: The satisfaction of patients with sedation by nursing staff is an issue of interest for the quality of health care, influencing the recovery and well-being of patients as well as their confidence in and adherence to treatment. One of the most frequently performed diagnostic and therapeutic tests requiring sedation are digestive endoscopies, so it would be interesting to study satisfaction in these services.

Aim: To determine the level of patient satisfaction and safety with sedation via digestive endoscopies by nurses.

Sensory neuropathy in patients with Pompe disease: a case series in Iran.

Background: Pompe disease is a glycogen storage disease primarily affecting striated muscles. Despite its main manifestation in muscles, patients with Pompe disease may exhibit non-muscle symptoms, such as hearing loss, suggesting potential involvement of sensory organs or the nervous system due to glycogen accumulation.

Aims: This study aimed to evaluate the presence of concomitant small and large fiber neuropathy in patients with Pompe disease.

Microalgae for bioremediation: advances, challenges, and public perception on genetic engineering.

The increase in the global population and industrial activities has led to an extensive use of water, the release of wastewater, and overall contamination of the environment. To address these issues, efficient treatment methods have been developed to decrease wastewater nutrient content and contaminants. Microalgae are a promising tool as a sustainable alternative to traditional wastewater treatment.

RNA profiles differ between small and large extracellular vesicle subsets isolated from porcine seminal plasma.

Background: Extracellular vesicles (EVs) are essential for cell-to-cell communication because they transport functionally active molecules, including proteins, RNA, and lipids, from secretory cells to nearby or distant target cells. Seminal plasma contains a large number of EVs (sEVs) that are phenotypically heterogeneous. The aim of the present study was to identify the RNA species contained in two subsets of porcine sEVs of different sizes, namely small sEVs (S-sEVs) and large sEVs (L-sEVs).

Adaptive or non-adaptive? Cranial evolution in a radiation of miniaturized day geckos.

Lygodactylus geckos represent a well-documented radiation of miniaturized lizards with diverse life-history traits that are widely distributed in Africa, Madagascar, and South America. The group has diversified into numerous species with high levels of morphological similarity. The evolutionary processes underlying such diversification remain enigmatic, because species live in different ecological biomes, ecoregions and microhabitats, while suggesting strikingly high levels of homoplasy.

Measurement distance effects on [Formula: see text]-symmetric Taylor patterns with optimal transition integer [Formula: see text] and with reduced inner sidelobes.

The following paper presents the findings of a study conducted on the distances at which the field generated by a ϕ-symmetric circular Taylor aperture distribution can be classified as far-field, and also the efficiency across various study parameters. The [Formula: see text] transition integers that produce a monotonic distribution, which have been traditionally used and analyzed, are compared with those that yield a peaked distribution, and offer greater efficiency. Additionally, modified circular Taylor [Formula: see text] distributions featuring synthesized patterns with one or two depressed inner sidelobes, which have not been previously explored, are also examined.

Human brain aging is associated with dysregulation of cell type epigenetic identity.

Significant links between aging and DNA methylation are emerging from recent studies. On the one hand, DNA methylation undergoes changes with age, a process termed as epigenetic drift. On the other hand, DNA methylation serves as a readily accessible and accurate biomarker for aging.

Automated MRI pituitary structured reporting from free-text using a fine-tuned Llama model: a feasibility study.

Background And Objective: Structured reports in radiology have demonstrated substantial advantages over unstructured ones. However, the transition from unstructured to structured reporting can face challenges, as experienced radiologists worry about the potential loss of valuable information. In this study, we fine-tuned the Llama 2 model capable of generating structured pituitary MRI reports from unstructured reports.

Transposon-triggered epigenetic chromatin dynamics modulate EFR-related pathogen response.

Infectious diseases drive wild plant evolution and impact crop yield. Plants, like animals, sense biotic threats through pattern recognition receptors (PRRs). Overly robust immune responses can harm plants; thus, understanding the tuning of defense response mechanisms is crucial for developing pathogen-resistant crops.

Spirituality in Managing Perceived Stress and Promoting Self-Care: A Descriptive Study on Nursing Students in Spain.

The relationship between spirituality, perceived stress, and self-care was examined in a sample of 515 nursing students in Spain. Using the perceived stress scale (PSS), the professional self-care scale (PSCS), and the spirituality questionnaire (MiLS-sp/sf), the findings indicated that higher spirituality, particularly through inner peace and faith, was linked to reduced stress and enhanced self-care across physical, inner, and social dimensions. However, the inner self-care dimension was the least developed, suggesting that essential emotional, spiritual, and psychological needs were neglected.

Integrating Ecological Suitability and Socioeconomic Feasibility at Landscape Scale to Restore Biodiversity and Ecosystem Services in Southern Chile.

Deforestation and forest degradation are key drivers of biodiversity loss and global environmental change. Ecosystem restoration is recognized as a global priority to counter these processes. Forest restoration efforts have commonly adopted a predominantly ecological approach, without including broader socioeconomic variables and the characteristics of the rural context.

Pre-extraction alveolar buccal bone overbuilding: a preclinical investigation.

Background: The pre-extraction overbuilding procedure was designed aiming to mitigate buccal bone resorption following tooth extraction. The objective of this study was to compare the efficacy of pre-extraction and juxta-extraction buccal overbuilding treatments in preserving buccal bone volume following tooth extraction.

Material And Methods: At the test sites (pre-extraction sites), an alveolar crest overbuilding was performed on the buccal aspect of the distal root of the fourth premolar using a xenograft covered with a collagen membrane.

Empowerment among breast cancer survivors using an online peer support community.

Objectives: Breast cancer (BC) impacts the patients' quality of life. Peer support can provide emotional understanding and enhances access to information, social support, coping strategies, and empowerment. Comunitats is an online peer support community app for BC survivors that involves healthcare professionals.

Ecological and anthropogenic effects on the genomic diversity of lemurs in Madagascar.

Ecological variation and anthropogenic landscape modification have had key roles in the diversification and extinction of mammals in Madagascar. Lemurs represent a radiation with more than 100 species, constituting roughly one-fifth of the primate order. Almost all species of lemurs are threatened with extinction, but little is known about their genetic diversity and demographic history.

The total electric charge and time of application of galvanic currents to macrophages can optimize the release of IL-1β with low cell death.

Galvanic current has been emerging as a novel therapy to regenerate chronic tissue lesions, including musculoskeletal and dermatological lesions. Recently, the NLRP3 inflammasome and IL-1β release have been identified as a signaling pathway triggered upon galvanic current application. However, the parameters for the clinical application of galvanic current remain subjective to the experience of the facultative in charge.

General physical impairments in migraine patients beyond cervical function.

Previous research has focused on the possibility of cervical dysfunction in migraine patients, similar to what is observed in patients with tension-type headaches. However, there is no evidence concerning the physical function of other body regions, even though lower levels of physical activity have been reported among migraine patients. The aim of this study was to compare cervical and extra-cervical range of motion, muscular strength, and endurance, as well as overall levels of physical activity, between patients with chronic migraine (CM) and asymptomatic participants.

Talbot effect based sensor measuring grating period change in subwavelength range.

Talbot length, the distance between two consecutive self-image planes along the propagation axis for a periodic diffraction object (grating) illuminated by a plane wave, depends on the period of the object and the wavelength of illumination. This property makes the Talbot effect a straightforward technique for measuring the period of a periodic object (grating) by accurately determining the Talbot length for a given illumination wavelength. However, since the Talbot length scale is proportional to the square of the grating period, traditional Talbot techniques face challenges when dealing with smaller grating periods and minor changes in the grating period.