What Lies Beyond Personality Traits? The Role of Intolerance of Uncertainty, Anxiety Sensitivity, and Metacognition.

Background: Although personality trait models have become consolidated as the hegemonic taxonomical models for describing personality and provide excellent capacity for predicting variables of psychological interest (i.e., mental disorders), there are still important gaps in our knowledge about personality traits predict those variables.

Comparing Traditional and Technology-Based Methods for Executive Function and Attention Training in Moderate Alzheimer's Dementia.

Background: Background: This study investigates the effects of cognitive interventions on executive functions and attention in patients with moderate Alzheimer's, comparing traditional and technology-based methods with a control group.

Method: A randomized controlled trial was conducted with 112 participants, divided into three groups: traditional intervention, technology-based intervention, and control group. Sixteen sessions were carried out, assessed using standardized tests and applying hierarchical linear mixed models to adjust for confounding factors and random effects.

Predictors and Moderators of Panic Disorder: Cognitive Behavioral Therapy vs. Acceptance and Commitment Therapy.

Background: Understanding variables that influence therapy outcomes can improve the results of interventions and reduce socio-health costs. The current study examined possible predictors and moderators of outcome (age, gender, duration of panic disorder, motivation to change, conscientiousness, and experiential avoidance) in Cognitive Behavioral Therapy (CBT) and Acceptance and Commitment Therapy (ACT).

Method: Eighty participants with a diagnosis of panic disorder, 56 women and 24 men, with an average age of 38 years, received 12 group sessions of CBT or ACT.

Social Support Increases Resilience and Affect in Non-Displaced Ukrainians and Refugees After a Year of War.

Background: This study investigates the impact of social support on resilience and affect among Ukrainian individuals affected by war (non-displaced persons and refugees), one year after the onset of the conflict.

Method: A total of 344 participants were recruited and categorized into two groups: non-displaced individuals and refugees. Measures included the Scale of Positive and Negative Experience (SPANE), the Brief Resilient Coping Scale (BRCS), and the Multidimensional Scale of Perceived Social Support (MSPSS).

The Impact and Consequences of Correcting for Acquiescence When Correlated Residuals are Present.

Background: In spite of the interest generated by controlling variance unrelated to the content in personality measures, few studies have assessed the combined impact of acquiescence (ACQ) and correlated residuals in the factor-analytic structural solutions that serve as a basis for item calibration.

Method: This article compares three control procedures in databases that simultaneously exhibit acquiescence (ACQ) and correlated residuals: the SIREN method (; ACQ control), the MORGANA method (; ; correlated residuals control), and a combined double control method. A 'control' procedure was also examined in which the presence of both determinants was ignored.

A Scale for Evaluating the Methodological Quality of Studies Based on Observational Methodology.

Background: To date, no studies have shown validity evidence of a scale that measures the methodological quality of studies based on observational methodology (SBOM). This study presents validity evidence of the Methodological Quality Scale for Studies based on Observational Methodology (MQSOM) based on its internal structure.

Method: MQSOM was applied to 650 journal articles that used observational methodology.

Ascending aortic replacement versus aortic root replacement in patients with type A aortic dissection involving the aortic root.

Background: Extensive surgical resection of the thoracic aorta in patients with type A aortic dissection (TAAD) is thought to reduce the risk of late aortic wall degeneration and the need for repeat aortic operations.

Objectives: We evaluated the early and late outcomes after aortic root replacement and supracoronary ascending aortic replacement in patients with TAAD involving the aortic root.

Design: Retrospective, multicenter cohort study.

Polymorphic Single-Nucleotide Variants in miRNA Genes and the Susceptibility to Colorectal Cancer: Combined Evaluation by Pairwise and Network Meta-Analysis, Thakkinstian's Algorithm and FPRP Criterium.

Background: Considerable epidemiological studies have examined the correlation between polymorphic single-nucleotide variants (SNPs) in miRNA genes and colorectal carcinoma (CRC) risk, yielding inconsistent results. Herein, we sought to systematically investigate the association between miRNA-SNPs and CRC susceptibility by combined evaluation using pairwise and network meta-analysis, the FPRP analysis (false positive report probability), and the Thakkinstian's algorithm.

Methods: The MEDLINE, EMBASE, WOS, and Cochrane Library databases were searched through May 2024 to find relevant association literatures.

Differential expression of CCD4(4B) drives natural variation in fruit carotenoid content in strawberry (Fragaria spp.).

Carotenoids are a diverse group of pigments imparting red, orange, and yellow hues to many horticultural plants, also enhancing their nutritional properties and health benefits. In strawberry, the genetic and molecular mechanisms regulating the natural variation of fruit carotenoid composition remain largely unexplored. In this study, we use a population segregating in yellow/white flesh to detect a major quantitative trait locus (QTL), qYellow Flesh-4B, located on chromosome 4B and accounting for 82% of total phenotypic variation.

An International Survey on the Use of a Polyrevitalizing Solution With or Without Other Aesthetic Procedures in the Daily Practice of Aesthetic Physicians.

Objective: NCTF135HA, a versatile polyrevitalizing solution, is a potent agent for enhancing skin quality, radiance, moisture, vitality, and diminishing fine wrinkles caused by aging factors. Data demonstrate a divergence in its application from skin quality enhancement to treatment of vitiligo lesions. To know more precisely about the protocol of use among providers, alone or in combination with other procedures, we performed an international survey.

Peptide-Drug Conjugate for Therapeutic Reprogramming of Tumor-Associated Macrophages in Breast Cancer.

In triple-negative breast cancer (TNBC), pro-tumoral macrophages promote metastasis and suppress the immune response. To target these cells, a previously identified CD206 (mannose receptor)-binding peptide, mUNO was engineered to enhance its affinity and proteolytic stability. The new rationally designed peptide, MACTIDE, includes a trypsin inhibitor loop, from the Sunflower Trypsin Inhibitor-I.

The relationship between primate distal fibula trabecular architecture and arboreality, phylogeny and size.

The fibula, despite being traditionally overlooked compared to the femur and the tibia, has recently received attention in primate functional morphology due to its correlation with the degree of arboreality (DOA). Highlighting further fibular features that are associated with arboreal habits would be key to improving palaeobiological inferences in fossil specimens. Here we present the first investigation on the trabecular bone structure of the primate fibula, focusing on the distal epiphysis, across a vast array of species.

Dual Interface Modification for Reduced Nonradiative Recombination in n-i-p Methylammonium-Free Perovskite Solar Cells.

High defect concentrations at the interfaces are the basis of charge extraction losses and instability in perovskite solar cells. Surface engineering with organic cations is a common practice to solve this issue. However, the full implications of the counteranions of these cations for device functioning are often neglected.

FFR-Negative Nonculprit High-Risk Plaques and Clinical Outcomes in High-Risk Populations: An Individual Patient-Data Pooled Analysis From COMBINE (OCT-FFR) and PECTUS-obs.

Background: Despite fractional flow reserve (FFR)-guided deferral of revascularization, recurrent events in patients with diabetes or after myocardial infarction remain common. This study aimed to assess the association between FFR-negative but high-risk nonculprit lesions and clinical outcomes.

Methods: This is a patient-level pooled analysis of the prospective natural-history COMBINE (OCT-FFR) study (Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients) and PECTUS-obs study (Identification of Risk Factors for Acute Coronary Events by OCT After STEMI and NSTEMI Patients With Residual Non- Flow Limiting Lesions).

Pickering Emulsions as Catalytic Systems in Food Applications.

Enzyme catalysis is important in food processing, such as in baking, dairy, and fiber processing and beverages. A recent advancement in catalysis is the development of Pickering emulsions as enzymatic catalytic systems; however, the use of Pickering emulsions (PEs) as catalytic systems in foods remains largely underdeveloped. Challenges exist that inhibit the widespread adoption of PEs as catalytic systems in foods.

Photon antibunching in single-molecule vibrational sum-frequency generation.

Sum-frequency generation (SFG) enables the coherent upconversion of electromagnetic signals and plays a significant role in mid-infrared vibrational spectroscopy for molecular analysis. Recent research indicates that plasmonic nanocavities, which confine light to extremely small volumes, can facilitate the detection of vibrational SFG signals from individual molecules by leveraging surface-enhanced Raman scattering combined with mid-infrared laser excitation. In this article, we compute the degree of second order coherence ( (0)) of the upconverted mid-infrared field under realistic parameters and accounting for the anharmonic potential that characterizes vibrational modes of individual molecules.

Modulation of surface phonon polaritons in MoO via dynamic doping of SiC substrate.

Polar biaxial crystals with extreme anisotropy hold promise for the spatial control and the manipulation of polaritons, as they can undergo topological transitions. However, taking advantage of these unique properties for nanophotonic devices requires to find mechanisms to modulate dynamically the material response. Here, we present a study on the propagation of surface phonon polaritons (SPhPs) in a photonic architecture based on a thin layer of α-MoO deposited on a semiconducting 4H-SiC substrate, whose carrier density can be tuned through photoinduction.

Coupled acoustoplasmonic resonators: the role of geometrical symmetries.

Acoustoplasmonic resonators, such as nanobars and crosses, are efficient acousto-optical transducers. The excitation of mechanical modes in these structures strongly depends on the spatial profile of the eigenmodes of the resonator. Using a system of two identical gold elongated bars placed on a silicon dioxide substrate, we examine how breaking mirror symmetries affects the optical and acoustic properties to provide insights in the design of acoustoplasmonic metasurfaces for nonsymmetric acousto-optical transducers.

Detection of clinically relevant variants in the gene below 10% allelic frequency: A multicenter study by ERIC, the European Research Initiative on CLL.

In chronic lymphocytic leukemia, the reliability of next-generation sequencing (NGS) to detect variants ≤10% allelic frequency (low-VAF) is debated. We tested the ability to detect 23 such variants in 41 different laboratories using their NGS method of choice. The sensitivity was 85.

The role of light in regulating plant growth, development and sugar metabolism: a review.

Light provides the necessary energy for plant photosynthesis, which allows plants to produce organic matter and energy conversion, during plant growth and development. Light provides material energy to plants as the basis for cell division and differentiation, chlorophyll synthesis, tissue growth and stomatal movement, and light intensity, photoperiod, and light quality play important roles in these processes. There are several regulatory mechanisms involved in sugar metabolism in plants, and light, as one of the regulatory factors, affects cell wall composition, starch granules, sucrose synthesis, and vascular bundle formation.

Developing and evaluating a health pack to support dog owners to manage the weight of their companion animals.

Introduction: Obesity is a serious and prevalent problem in dogs. The causes are multifactorial, but owners play a key role and so this paper reports the development and evaluation of a health pack designed to help owners to manage the weight of their dogs.

Method: The pack was informed by previous research, behavior change theory (i.

Comparative analysis of anticoagulant influence on PMI estimation based on porcine blood metabolomics profile measured using GC-MS.

Introduction: Accurate post-mortem interval (PMI) estimation is essential in forensic investigations. Although various methods for PMI determination have been developed, only an approximate estimation is still achievable, and an accurate PMI indication is still challenging. Therefore, in this study, we employed gas chromatography-mass spectrometry (GC-MS)-based metabolomics to assess post-mortem changes in porcine blood samples collected with and without the addition of anticoagulant (EDTA).

VACCIMEL, an allogeneic melanoma vaccine, efficiently triggers T cell immune responses against neoantigens and alloantigens, as well as against tumor-associated antigens.

VACCIMEL is a therapeutic cancer vaccine composed of four irradiated allogeneic human melanoma cell lines rationally selected to cover a wide range of melanoma tumor-associated antigens (TAA). We previously demonstrated that vaccination in the adjuvant setting prolonged the distant-metastasis-free survival of cutaneous melanoma patients and that T cells reactive to TAA and the patient's private neoantigens increased during treatment. However, immune responses directed to vaccine antigens that may arise from VACCIMEL's somatic mutations and human polymorphisms remain unexplored.

Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care.

Introduction: This multicenter prospective study sponsored by the (GETH-TC) explores the use of frailty assessments in allo-HCT candidates.

Methods: Frailty was measured using the HCT Frailty Scale at first consultation and HCT admission in 404 adults from 15 HCT programs in Spain. Based on the results, patients were classified into fit, pre-frail and frail categories.