758,757 results match your criteria: "Spain; Hospital Clinico Universitario 'Lozano Blesa'[Affiliation]"

The CASE of brand names during sentence reading.

Psychol Res

December 2024

Dpto Metodología and ERI-Lectura, Universitat de València, Av. Blasco Ibáñez, 21; 46010, Valencia, Spain.

Brand names typically maintain a distinctive letter case (e.g., IKEA, Google).

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Effect of eccentric-based resistance exercise on bone (re)modelling markers across the menstrual cycle and oral contraceptive cycle.

Eur J Appl Physiol

December 2024

LFE Research Group, Department of Health and Human Performance. Faculty of Physical Activity and Sport Sciences, Universidad Politécnica de Madrid, Calle de Martín Fierro, 7, 28040, Madrid, Spain.

Purpose: To investigate the acute effects of eccentric-based resistance exercise and sex-hormone fluctuations on P1NP and β-CTX-1 concentrations in premenopausal females.

Methods: Nine eumenorrheic females and ten oral contraceptive (OC) users performed eccentric-based resistance exercise, consisted of 10 × 10 repetitions of parallel back squats with a 4-s eccentric phase, in the early-follicular (EFP), late-follicular (LFP) and mid-luteal (MLP) phases of the menstrual cycle (MC) or in the withdrawal (WP) and active pill-taking (APP) phases of the OC cycle.

Results: 17β-oestradiol (pg·ml) was lower in EFP (36.

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Background: Oropharyngeal squamous cell carcinoma (OPSCC) of human papillomavirus (HPV)-positive status is increasing relative to HPV-negative disease. Nutritional features of OPSCC patients according to HPV status is unclear.

Subjects/methods: Canadian and Spanish patients with OPSCC were assessed for body mass index (BMI), weight loss grade (WLG), and computed tomography-defined skeletal muscle index (SMI).

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Explaining the influence of biophilic design on employee well-being.

Sci Rep

December 2024

Facultad de Ciencias Económicas y Empresariales, Universidad Pontificia Comillas, Alberto Aguilera, 23, 28015, Madrid, Spain.

Biophilic workplace design has been proposed as an effective strategy to increase employee well-being in open-plan offices. To expand our understanding of why and for whom indoor nature exposure increases well-being, the aim of this study was to evaluate vigor as a mediator and to examine whether nature relatedness is a direct antecedent of nature exposure or a moderator of the relationship between exposure to nature and vigor. Based on longitudinal data obtained from a two-wave panel design with white-collar workers in open-plan offices (Study 1, n = 345; Study 2, n = 291), using a rival model strategy and two dependent variables, i.

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Advances in the fMRI analysis of the default mode network: a review.

Brain Struct Funct

December 2024

Departamento de Psicobiología y Metodología en Ciencias del Comportamiento, Facultad de Psicología, Universidad Complutense de Madrid, Pozuelo de Alarcón, 28223, Madrid, Spain.

The default mode network (DMN) is a singular pattern of synchronization between brain regions, usually observed using resting-state functional magnetic resonance imaging (rs-fMRI) and functional connectivity analyses. In comparison to other brain networks that are primarily involved in attentional-demanding tasks (such as the frontoparietal network), the DMN is linked with self-referential activities, and alterations in its pattern of connectivity have been related to a wide range of disorders. Structural connectivity analyses have highlighted the vital role of the posterior cingulate cortex and the precuneus as integrative hubs, and advanced parcellation methods have further contributed to elucidate the DMN's regions, enriching its explanatory potential across cognitive functions and dysfunctions.

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Treatment of acromegaly-induced diabetes: an updated proposal.

Pituitary

December 2024

Endocrinology & Nutrition Department, Hospital Universitario Germans Trias i Pujol. CIBERER U747 (ISCIII), Universitat Autònoma de Barcelona, Badalona, Spain.

Acromegaly-induced diabetes presents unique features due to the direct effects of excess growth hormone (GH) and insulin-like growth factor 1 (IGF-) on glucose metabolism, especially insulin resistance in association to low body fat content and water retention. Increased cardiovascular risk is much higher when acromegaly is complicated with diabetes, thus requiring a holistic management that addresses also these specific characteristics which differ from those of classical type 2 diabetes.The optimal management of diabetes in acromegaly requires not only an effective control of carbohydrate disturbances per se, but also the concurrent control of GH hypersecretion as it will directly impact on glucose control.

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Purpose: Early and accurate identification of the risk of psychological distress allows for timely intervention and improved prognosis. Current methods for predicting psychological distress among lung cancer patients using readily available data are limited. This study aimed to develop a robust machine learning (ML) model for determining the risk of psychological distress among lung cancer patients.

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With rising demand for electricity, integrating renewable energy sources into power networks has become a key challenge. The fast incorporation of clean energy sources, particularly solar and wind power, into the existing power grid in the last several years has raised a major problem in controlling and managing the power grid due to the intermittent nature of these sources. Therefore, in order to ensure the safe RES integration providing high-quality power at a fair price and for the secure and reliable functioning of electrical systems, a precise one-day-ahead solar irradiation and wind speed forecast is essential for a stable and safe hybrid energy system.

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Affective feelings exert a powerful influence on decision making, even when the source of those feelings is incidental, i.e., unrelated to the decision at hand.

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Inducing cylindrical and spherical defocus after implantation with new generation intraocular lenses improves intermediate and near visual acuity.

Sci Rep

December 2024

Imaging, Biomechanics and Mathematical Modelling Solutions Lab, Narayana Nethralaya Foundation, Bangalore, India.

An induced cylinder and spherical power after implantation with an extended depth of focus (EDOF) and enhanced monofocal intraocular lens (IOL) could improve distance, intermediate (60 cm) and near (40 cm) visual acuity (VA). In this prospective study, forty eyes with Eyhance EDOF IOL (Johnson and Johnson, USA) and 40 eyes with Vivity EDOF IOL (Alcon Laboratories Inc. USA) were included.

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Burning of municipal waste in household furnaces and the health of their owners.

Sci Rep

December 2024

Prospecting and Environment Laboratory (Promediam), Universidad Politecnica de Madrid, Alenza 4, 28003, Madrid, Spain.

The aim of the study was to determine the scale of emission and airborne dispersion of selected pollutants (PM2.5, PM10, TVOC, HCHO) associated with the combustion of various types of municipal waste (MW), its mixed stream and separate fractions, in a household furnace, as compared to conventional (CF) and alternative (AF) fuels. We demonstrated that each type of fuel (AF, CF, AFw) combusted in a household furnace is a significant source of air pollutants, especially fine PM2.

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During the COVID-19 pandemic, effective public policy interventions have been crucial in combating virus transmission, sparking extensive debate on crisis management strategies and emphasizing the necessity for reliable models to inform governmental decisions, particularly at the local level. Leveraging disaggregated socio-demographic microdata, including social determinants, age-specific strata, and mobility patterns, we design a comprehensive network model of Catalonia's population and, through numerical simulation, assess its response to the outbreak of COVID-19 over the two-year period 2020-21. Our findings underscore the critical importance of timely implementation of broad non-pharmaceutical measures and effective vaccination campaigns in curbing virus spread; in addition, the identification of high-risk groups and their corresponding maps of connections within the network paves the way for tailored and more impactful interventions.

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The warm Western Boundary Currents (WBCs) and their zonal extensions are persistent, deep, strong and narrow oceanic currents. They are known to anchor and energize the Extra-Tropical storm tracks by frontal thermal air-sea interactions. However, even in the latest generation of climate models, WBCs are characterized by large biases, and both the present storm-track activity and its recent intensification are poorly estimated.

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Nodal loop semimetals are topological materials with drumhead surface states characterized by reduced kinetic energy. If the Fermi energy of such a system is near these nondispersive states interaction among charge carriers substantially impacts their electronic structure. The emergence of magnetism in these surface states is one of the possible consequences.

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This study investigates the ablation performance of Inconel 718, a nickel-based superalloy, and metal matrix polycrystalline diamond (MMPCD), a super composite, using a nano-second (ns) pulsed laser across a range of ablation conditions. Single trenches varying in energy fluence and scanning speeds were created, analyzing the experimental responses in terms of ablation rate and surface roughness. Using regression techniques, models were developed to understand these relationships.

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Untangling areas of improvement in secondary prevention of ischemic stroke in patients with atrial fibrillation.

Sci Rep

December 2024

Health Services Research and Pharmacoepidemiology Unit, Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO), Avenida Cataluña, 21, 46020, Valencia, Spain.

Improvement of post-stroke outcomes relies on patient adherence and appropriate therapy maintenance by physicians. However, comprehensive evaluation of these factors is often overlooked. This study assesses secondary stroke prevention by differentiating patient adherence to antithrombotic treatments (ATT) from physician-initiated interruptions or switches.

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Regressions on quantum neural networks at maximal expressivity.

Sci Rep

December 2024

Departamento de Física, Universidad Carlos III de Madrid, Avda. de la Universidad 30, 28911, Leganés, Spain.

Considering a universal deep neural network organized as a series of nested qubit rotations, accomplished by adjustable data re-uploads we analyze its expressivity. This ability to approximate continuous functions in regression tasks is quantified making use of a partial Fourier decomposition of the generated output and systematically benchmarked with the aid of a teacher-student scheme. While the maximal expressive power increases with the depth of the network and the number of qubits, it is fundamentally bounded by the data encoding mechanism.

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Analyzing bacterial networks and interactions in skin and gills of Sparus aurata with microalgae-based additive feeding.

Sci Rep

December 2024

Department of Microbiology, Faculty of Sciences, CEI·MAR-International Campus of Excellence in Marine Science, University of Malaga, Málaga, Spain.

The inclusion of microalgae in functional fish diets has a notable impact on the welfare, metabolism and physiology of the organism. The microbial communities associated with the fish are directly influenced by the host's diet, and further understanding the impact on mucosal microbiota is needed. This study aimed to analyze the microbiota associated with the skin and gills of Sparus aurata fed a diet containing 10% microalgae.

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The Auxin Response Factors (ARFs) family of transcription factors are the central mediators of auxin-triggered transcriptional regulation. Functionally different classes of extant ARFs operate as antagonistic auxin-dependent and -independent regulators. While part of the evolutionary trajectory to the present auxin response functions has been reconstructed, it is unclear how ARFs emerged, and how early diversification led to functionally different proteins.

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Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To overcome these bottlenecks, we present the Theranostic Genome, the part of the human genome whose expression can be utilized to combine therapeutic and diagnostic applications.

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Conjugative plasmids promote the dissemination and evolution of antimicrobial resistance in bacterial pathogens. However, plasmid acquisition can produce physiological alterations in the bacterial host, leading to potential fitness costs that determine the clinical success of bacteria-plasmid associations. In this study, we use a transcriptomic approach to characterize the interactions between a globally disseminated carbapenem resistance plasmid, pOXA-48, and a diverse collection of multidrug resistant (MDR) enterobacteria.

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Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota.

Nat Commun

December 2024

AZTI, Marine Research, Basque Research and Technology Alliance (BRTA), Sukarrieta, Spain.

Marine brown algae produce the highly recalcitrant polysaccharide fucoidan, contributing to long-term oceanic carbon storage and climate regulation. Fucoidan is degraded by specialized heterotrophic bacteria, which promote ecosystem function and global carbon turnover using largely uncharacterized mechanisms. Here, we isolate and study two Planctomycetota strains from the microbiome associated with the alga Fucus spiralis, which grow efficiently on chemically diverse fucoidans.

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Strontium isotope (Sr/Sr) analysis with reference to strontium isotope landscapes (Sr isoscapes) allows reconstructing mobility and migration in archaeology, ecology, and forensics. However, despite the vast potential of research involving Sr/Sr analysis particularly in Africa, Sr isoscapes remain unavailable for the largest parts of the continent. Here, we measure the Sr/Sr ratios in 778 environmental samples from 24 African countries and combine this data with published data to model a bioavailable Sr isoscape for sub-Saharan Africa using random forest regression.

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Global Relative Importance of Denitrification and Anammox in Microbial Nitrogen Loss Across Terrestrial and Aquatic Ecosystems.

Adv Sci (Weinh)

December 2024

Danjiangkou Wetland Ecosystem Field Scientific Observation and Research Station, Chinese Academy of Sciences & Hubei Province, Wuhan, 430074, P.R. China.

Denitrification and anaerobic ammonium oxidation (anammox) are the major microbial processes responsible for global nitrogen (N) loss. Yet, the relative contributions of denitrification and anammox to N loss across contrasting terrestrial and aquatic ecosystems worldwide remain unclear, hampering capacities to predict the human alterations in the global N cycle. Here, a global synthesis including 3240 observations from 199 published isotope pairing studies is conducted and finds that denitrification governs microbial N loss globally (79.

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Many clinicians recommend that patients diagnosed with HPV-related gynecologic cancers receive prophylactic HPV vaccination at the time of cancer diagnosis or after cancer treatment. In view of the large use of such practice, we aimed to assess the literature evidence supporting the use of prophylactic HPV vaccines after diagnosis or treatment of HPV-related gynecologic cancers. Women who develop HPV-related cervical, vaginal, and vulvar cancers represent a subgroup of patients who may be particularly sensitive to HPV infection and re-acquire infections.

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