3 results match your criteria: "Southwestern Lu Hospital[Affiliation]"
A randomized non-inferiority study of low-dose and standard-dose ticagrelor after intervention for acute coronary syndrome: study protocol for the TIGER STUDY.
Trials
March 2022
The Department of Cardiology, Institute of Cardiovascular Diseases, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 200336, Shanghai, China.
Background: Current guidelines recommend that patients with acute coronary syndrome (ACS) who have successfully undergone percutaneous coronary intervention (PCI) should continue to use dual antiplatelet therapy (DAPT) for 12 months. The long-term use of standard-dose dual antiplatelet therapy will increase the risk of bleeding. An optimized antiplatelet strategy that can prevent ischemic events and reduce the risk of bleeding remains to be explored.
View Article and Find Full Text PDFCD13 Induces Autophagy to Promote Hepatocellular Carcinoma Cell Chemoresistance Through the P38/Hsp27/CREB/ATG7 Pathway.
J Pharmacol Exp Ther
September 2020
School of Pharmacy, Weifang Medical University, Weifang, Shandong, China (Y.Z., H.W., X.Xi., Y.M., S.J., X.Xu., X.Z., S.W., W.J., C.F., L.Z., F.Y., X.W.) and Department of pharmacy, Southwestern Lu Hospital, Liaocheng, Shandong, China (H.W.)
The chemoresistance of hepatocellular carcinoma (HCC) is a serious problem that directly hinders the effect of chemotherapeutic agents. We previously reported that Aminopeptidase N (CD13) inhibition can enhance the cytotoxic efficacy of chemotherapy agents. In the present study, we use liver cancer cells to explore the molecular mechanism accounting for the relationship between CD13 and chemoresistance.
View Article and Find Full Text PDFTransdermal permeation effect of collagen hydrolysates of deer sinew on mouse skin, ex vitro, and antioxidant activity, increased type I collagen secretion of percutaneous proteins in NIH/3T3 cells.
J Cosmet Dermatol
February 2020
Changchun University of Traditional Chinese Medicine, Changchun, China.
Article Synopsis
- The study investigates the transdermal effects of collagen hydrolysates extracted from deer sinew, which contains a high collagen content of 82.12%.
- The research assesses how effectively these hydrolysates can penetrate mouse skin and their impact on skin protection through antioxidant properties and collagen secretion in cells.
- Results indicate that around 8% of the collagen hydrolysates can penetrate the skin, promoting cell growth and collagen production, suggesting their potential use in cosmetics for skin protection against aging.