Larvae Meal Enhances Immune Response by Improving Serum Immunoglobulin, Intestinal Barrier and Gut Microbiota of Sichuan White Geese After Avian Influenza Vaccination.

Larvae Meal (HILM) has been observed to enhance growth performance and immune function, yet the effects and mechanisms in geese remain less understood. Experiment I included 64 Sichuan White Geese to investigate the optimal additive amount of HILM in diet, and experiment II included 32 Sichuan White Geese to access serum immunoglobulin, spleen immune-related genes, intestinal morphology and gut microbiota at the optimal additive amount of HILM. The results showed that the addition of 1% HILM significantly increased the ADG of Sichuan White Geese ( < 0.

Effects of Ammonia Stress on Liver Tissue Structure, Enzyme Activities, and Metabolome of Juvenile Largemouth Bass .

Ammonia, a ubiquitous contaminant in aquatic ecosystems, poses multifaceted threats to fish species at elevated concentrations. In order to investigate the toxic effects of chronic ammonia stress on the liver of juvenile , the present experiment was conducted to investigate the differences in changes in liver tissue structure, enzyme activities, and metabolomes after 28 days of ammonia exposure (0, 4, 8, and 16 mg/L). The findings revealed that ammonia exposure induced significant oxidative stress in the liver, manifesting in decreased activities of antioxidant enzymes SOD and GSH-Px, elevated levels of GSH, GST, and MDA, and heightened activities of immune enzymes LZM, ALP, and ACP.

Role of the Anaphase-Promoting Complex Activator Cdh1 in the Virulence of .

is a globally distributed human fungal pathogen that can cause cryptococcal meningitis with high morbidity and mortality. In this study, we identified an anaphase-promoting complex (APC) activator, Cdh1, and examined its impact on the virulence of . Our subcellular localization analysis revealed that Cdh1 is situated in the nucleus of .

Microwave Irradiation-Assisted Synthesis of Anisotropic Crown Ether-Grafted Bamboo Pulp Aerogel as a Chelating Agent for Selective Adsorption of Heavy Metals (M).

Crown ether is widely used in water purification because of its ring structure and good selective adsorption of specific heavy metals. However, its high cost and difficulty in recycling limit the purification of heavy metals in water. The anisotropic [2,4]-dibenzo-18-crown-6-modified bamboo pulp aerogel (DB18C6/PA) is successfully synthesized by microwave irradiation and directional freezing technology.

Himalaflavones F and G, two new flavonoids from the roots of Edgew with anti-inflammatory activity.

Himalaflavones F () and G (), two new flavonoids, along with eight known ones ()were isolated from the roots of Edgew. The chemical structures of these compounds were elucidated by 1D/2D NMR, UV and HR-ESI-ME data. Meanwhile, the anti-inflammatory activities of all isolates were test by using Griess method.

Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE pathway in endometriosis.

Introduction: Macranthoidin B is one of the primary and unique triterpenoid saponin metabolites from Hand. -Mazz, which is used to treat endometriosis (EMS) in traditional Chinese medicine. However, the effect of macranthoidin B remains unknown in EMS.

Concurrent Severe Fever with Thrombocytopenia Syndrome Virus Outbreaks on Multiple Fox Farms, China, 2023.

The role of farmed animals in the viral spillover from wild animals to humans is of growing importance. Between July and September of 2023 infectious disease outbreaks were reported on six Arctic fox () farms in Shandong and Liaoning provinces, China, which lasted for 2-3 months and resulted in tens to hundreds of fatalities per farm. Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) was identified in tissue/organ and swab samples from all the 13 foxes collected from these farms.

Nitrogen vacancy mediated g-CN/BiVO Z-scheme heterostructure nanostructures for exceptional photocatalytic performance.

In this work, a novel V-g-CN/BiVO (V-CN/BVO) Z-scheme heterojunction photocatalyst was formed by introducing nitrogen vacancies (V) and constructing heterojunction, which is able to efficiently degrade the representative contaminant rhodamine B (RhB) upon exposure to visible-light, resulting in an outstanding degradation rate of 98.91% of RhB within 30 min. This photocatalyst exhibits catalytic universality and allows the degradation of methylene blue (MB, 97.

Complete BmFib-L knockout reveals its indispensable role in silk fiber formation.

Silkworm (Bombyx mori), belonging to the order Lepidoptera, is an important model insect for economic and scientific research. The capacity of the silkworm to secrete robust silk renders it a valuable economic resource, while its biological characteristics offer insights into a number of scientific disciplines. Despite the extensive research conducted to elucidate the mechanisms of silk secretion, many aspects remain unclear.

The development of a waste management and classification system based on deep learning and Internet of Things.

Waste sorting is a key part of sustainable development. To maximize the recovery of resources and reduce labor costs, a waste management and classification system is established. In the system, we use Internet of Things (IoT) and edge computing to implement waste sorting and the systematic long-distance information transmission and monitoring.

Jujube Syrup and Starter YF-L922 Co-Fermentation of Yak Yogurt: Effects of Quality Properties, Antioxidative Activities and Structure.

Different percentages of jujube yrup (0%, 3%, 6% and 9%) were incorporated into yak milk and fermented using the fermenting agent . The quality characteristics and antioxidant activity of the resulting yogurt were evaluated at days 0, 7, 14, 21 and 28. The results indicated that the pH and acidity of the yogurt were not significantly influenced by the varying additions of jujube syrup during storage ( > 0.

The impact of the development level of rural e-commerce on the depressive symptoms among rural older adult individuals.

Background: In the context of China, where the demographic trend of population aging intertwines with the rapid advancement of information digitalization, rural older adult individuals, who are part of a vulnerable population, are witnessing a deteriorating depression status. The proliferation of rural e-commerce, which fuels the digital economic revolution in rural areas, is concurrently affecting the depressive symptoms among rural older adult individuals.

Methods: This study uses longitudinal data from the China Health and Retirement Longitudinal Study (CHARLS) and applies a multi-period Difference-in-Differences (DID) model to explore how rural e-commerce affects the depressive symptoms among rural older adult individuals.

[Construction of a recombinant strain expressing SpaA and CbpB of and evaluation of the strain immunogenicity in a mouse model].

To construct a recombinant strain expressing SpaA and CbpB of for oral administration, we constructed the recombinant plasmid pDG1730-CBJA by fusion PCR and seamless cloning. The plasmid was introduced into . KC strain by natural transformation, and the recombinant strain KC-- was screened out on the plate containing spectinomycin () and confirmed by PCR and starch degradation test.

[Research progress in animal embryo implantation and endometrial organoids].

Embryo implantation involves a complex interaction between the embryo and the endometrium of the mother, the study of which faces a variety of problems. The modeling of endometrial epithelial organoids and endometrial assembloids provides a new way to study the process of embryo implantation . This paper summarized the latest research progress in embryo implantation, the regulation mechanism of endometrial receptivity by estrogen- progesterone coordination and embryo-derived signals, the establishment of endometrial organoids, and the development and application of endometrial assembloids in the research on mother-embryo interaction, providing new strategies for studying the communication between embryo and maternal uterus during implantation.

[Advances in the anti-host interferon immune response of bluetongue virus].

Bluetongue virus (BTV) usually infects sheep, cattle, deer and other domesticated and wild ruminants through the bite of the vector insects, , causing bluetongue (BT). BT in subtropical and even temperate regions poses a serious threat to the development and international trade of the livestock industry. This article introduced the structure and cellular invasion, and summarized the mechanisms of anti-BTV immune response of host cells and antagonism of host cell innate immune response by the non-structural proteins (e.

[Advances in epigenetic regulation of the dioxygenase TET1].

Ten-eleven translocation 1 (TET1) protein is an alpha-ketoglutaric acid (α-KG) and Fe-dependent dioxygenase. It plays a role in the active demethylation of DNA by hydroxylation of 5-methyl-cytosine (5-mC) to 5-hydroxymethyl-cytosine (5-hmC). Ten-eleven translocation 1 (TET1) protein is involved in maintaining genome methylation homeostasis and epigenetic regulation.

Stable Pickering emulsions of cinnamaldehyde were formulated using tannic acid-assisted cellulose nanofibers and applied for mango preservation.

Recent explorations into cinnamaldehyde (CIN) have identified its potential as a natural preservative, particularly when incorporated into active packaging to enhance the shelf-life of fruits and vegetables. This study explores the use of cellulose nanofiber (CNF)-stabilized Pickering emulsions as a novel delivery system for essential oils, demonstrating broad applicability in food preservation strategies. We employ CNF as Pickering stabilizers to effectively emulsify and encapsulate CIN, investigating the influence of tannic acid (TA) concentrations on the stability of these emulsions.

Interplay between tobacco curly shoot virus vsiRNA24 and triosephosphate isomerase: implications for Nicotiana benthamiana viral defense.

Virus-derived small interfering RNAs (vsiRNAs) play an important role in viral infection by regulating the expression of host genes. At present, research on the regulation of plant primary metabolic pathways by vsiRNAs is very limited. TvsiRNA24 derived from tobacco curly shoot virus (TbCSV) was amplified by reverse transcription polymerase chain reaction, and its target gene NbTPI (triosephosphate isomerase) was verified using reverse transcription quantitative polymerase chain reaction and GFP fluorescence observation.

Highly catalytic CoFe-prussian blue analogue/ZIF-67 yolk-shell nanocube-decorated MBene nanosheets for ultrasensitive electrochemical cancer-specific neoantigen biosensor.

Neoantigens exclusively presented by human leukocyte antigens (HLAs) on cancer cell surfaces are newly discovered and highly cancer-specific biomarkers for cancer diagnosis. The current available method for detecting neoantigens is predominantly based on Mass spectrometry with inevitable limitations of high cost, complexity and isotope labels. In this work, we describe the development of an innovative catalytic electrochemical biosensor for ultrasensitive detection of neoantigen in cell lysates.

DNA lesion-gated dumbbell nanodevices enable on-demand activation of the cGAS-STING pathway for enhancing cancer immunotherapy.

Utilizing the cGAS-STING pathway to combat immune evasion is one of the most promising strategies for enhancing cancer immunotherapy. However, current techniques for activating the cGAS-STING pathway often face a dilemma, mainly due to the balance between efficacy and safety. Here, we develop a uracil base lesion-gated dumbbell DNA nanodevice (UBLE) that allows on-demand activation and termination of the cGAS-STING pathway in tumor cells, thereby enhancing cancer immunotherapy.

Evolution and comparative transcriptome analysis of glucosinolate pathway genes in L.

Glucosinolates (GSLs) are important secondary metabolites abundantly distributed in Brassicaceae plants, whose degradation products benefit plant resistance but are regarded as disadvantageous factors for human health. Thus, reducing GSL content is an important goal in the breeding program in crops, such as . In this study, 1280 genes in the GSL pathway were identified from 14 land plant genomes, which are specifically distributed in Brassicaceae and are extensively expanded in .

SNP loci identification and KASP marker development system for genetic diversity, population structure, and fingerprinting in sweetpotato (Ipomoea batatas L.).

Sweetpotato (Ipomoea batatas L.), an important food and industrial crop in the world, has a highly heterozygous hexaploid genome, making the development of single nucleotide polymorphism (SNP) markers challenging. Identifying SNP loci and developing practical SNP markers are crucial for genomic and genetic research on sweetpotato.

Bmpallidin, encoding a subunit of the BLOC-1 complex, is involved in urate granules formation in silkworm integument.

The abnormal development of urate granules in silkworm larvae leads to translucent mutants with a distinct transparent phenotype. Studies on such mutants are expected to enhance current understanding of uric acid metabolism. The hoarfrost translucent (oh) mutant exhibits a mottled, translucent larval integument due to the presence of smaller and irregularly shaped urate granules compared to wild-type individuals.

Enhancing the Built-in Electric Field in Oxygen Vacancies-Enriched I-Doped BiOCl for Visible Light-Driven Photocatalytic Oxidation.

In semiconductor catalysts, rational doping of nonmetallic elements holds significant scientific and technological importance for enhancing photocatalytic performance. Here, using a one-step hydrothermal technique, we synthesized iodine-doped BiOCl composite and evaluated the impact of iodine doping on its photocatalytic capability for organic dye degradation under visible light irradiation. In this study, we demonstrate that the introduction of iodide ions not only provides an ideal built-in electric field (BIEF) for BiOCl but also induces the generation of additional oxygen vacancies (OVs).

Fast Kinetics Enabled by Ion Enrichment Layer for Dendrite-Free Zinc Anode.

Aqueous zinc-ion batteries (AZIBs) are considered a promising choice for energy storage devices owing to the excellent safety and favorable capacity of the Zn anode. However, the uncontrolled dendrite growth of Zn anode severely constrains the practical applications of AZIBs. Herein, a novel ion enrichment layer of CuS is designed and constructed on the Zn foil surface to achieve dendrite-free Zn anode.