Jujube Syrup and Starter YF-L922 Co-Fermentation of Yak Yogurt: Effects of Quality Properties, Antioxidative Activities and Structure.

Different percentages of jujube yrup (0%, 3%, 6% and 9%) were incorporated into yak milk and fermented using the fermenting agent . The quality characteristics and antioxidant activity of the resulting yogurt were evaluated at days 0, 7, 14, 21 and 28. The results indicated that the pH and acidity of the yogurt were not significantly influenced by the varying additions of jujube syrup during storage ( > 0.

DNA lesion-gated dumbbell nanodevices enable on-demand activation of the cGAS-STING pathway for enhancing cancer immunotherapy.

Utilizing the cGAS-STING pathway to combat immune evasion is one of the most promising strategies for enhancing cancer immunotherapy. However, current techniques for activating the cGAS-STING pathway often face a dilemma, mainly due to the balance between efficacy and safety. Here, we develop a uracil base lesion-gated dumbbell DNA nanodevice (UBLE) that allows on-demand activation and termination of the cGAS-STING pathway in tumor cells, thereby enhancing cancer immunotherapy.

Tunable band alignment and large power conversion efficiency in a two-dimensional InS/ZnInS heterostructure.

Heterostructures can efficiently modulate the bandgap of semiconductors and enhance the separation of photocarriers, thereby enhancing the performance of optoelectronic devices. Herein, we design an InS/ZnInS van der Waals (vdW) heterostructure and investigate its electronic and photovoltaic properties using first principles calculation. Compared to its individual monolayers, the InS/ZnInS heterostructure not only possesses a smaller band gap of 2.

The formation mechanism of metal cluster fullerenes ScN@C: force field development and molecular dynamics simulations.

Metal cluster fullerenes are a class of molecular nanomaterials with complex structures and novel properties. An in-depth study of their formation mechanism is a key topic for developing new high-yield synthesis methods and promoting the practical application of such molecular nanomaterials. To elucidate the formation mechanism of ScN@C, a representative sub-class of metal cluster fullerenes, this study developed a ReaxFF force field parameter set CNSc.

[Chemical constituents and anti-inflammatory activity of Dracocephalum tanguticum].

The chemical constituents of Dracocephalum tanguticum were investigated using normal-and reverse-phase silica gel column chromatography, RP-HPLC, and other separation techniques, combined with experimental methods such as NMR, UV, IR, MS, and ORD, as well as comparison with reported literature data. From the ethanol extract of D. tanguticum, 10 compounds were isolated and identified: dracotangusion C(1),(1R,4S,5S,10R)-(+)-germacrone-1(10)-4-diepoxide(2), 1β,4β,5β-trihydroxy-7(11),9-germacradien-8-one(3), curcumadione(4), β-sitosterol(5), lilacoside(6), diosmetin-7-O-β-D-glucopyranoside(7), diosmin(8), luteolin-7-O-glucoside(9), and luteolin(10).

The new genus (Lepidoptera, Crambidae, Spilomelinae), with descriptions of two new species from China.

The male genitalia characters of four species, Walker, 1859, Yamanaka, 1998, Walker, 1859 and Singh et Ahmad, 2022, placed in the genus Moore, 1888 before the present study, do not conform to the diagnosis of . A new genus, , is established for these four species, and two new species, and are described based on their external morphology and genitalia characters. is designated as the type species of the new genus.

Modifications in Protein Structure and Xanthine Oxidase Inhibition of Yak Casein Induced by Protease Treatment.

Yak milk is abundant in casein, which can generate a variety of bioactive peptides through enzymatic hydrolysis. However, the influence of enzymatic hydrolysis on the structural properties of yak casein and its inhibitory effects on xanthine oxidase (XOD) remain largely unexplored. This study demonstrated that when yak casein was subjected to treatment with flavourzyme, the degree of hydrolysis progressively increased over time, resulting in the fragmentation of the casein's flake-like structure into smaller particles.

 (Asteraceae), a new species from Xizang (Tibet), China.

, a new species of Asteraceae from the Xizang (Tibet) Autonomous Region of China, is described and illustrated here. Morphologically, it is most similar to but can be distinguished by the combination of monoecious and dioecious individuals, involucral bracts arranged in 3-5 series (with outer series herbaceous and middle to inner series membranous), fimbriate apices on female florets, rough-edged lobes on male florets, and achenes lacking costae. Phylogenetic analyses further support the separation of this new species from related taxa.

Separation and purification of antioxidant peptides from Maxim. cake meal and study of conformational relationship between them.

In this study, peptides were isolated and purified from Maxim. cake meal for the first time, with the aim of discovering peptides with excellent antioxidant properties. Peptides were isolated and purified from the cake meal using ultrafiltration and dextran gel chromatography.

Description of six new crab-spider species and first description of the male of Liu & Yao, 2023 from Medog, Xizang, China (Araneae, Thomisidae).

Seven species of the crab-spider family Thomisidae from Medog, Xizang, China are described here, including six new species: Wang, Lu & Zhang, (♂♀), Wang, Lu & Zhang, (♂♀), Wang, Lu & Zhang, (♂♀), Wang, Lu & Zhang, (♂♀), Wang, Lu & Zhang, (♂♀), and Wang, Lu & Zhang, (♂♀). The male of Liu & Yao, 2023 is described here for the first time. Descriptions and photographs of all the species are provided.

Interaction between intestinal mycobiota and microbiota shapes lung inflammation.

Gut microbiota is an intricate microbial community containing bacteria, fungi, viruses, archaea, and protozoa, and each of them contributes to diverse aspects of host health. Nevertheless, the influence of interaction among gut microbiota on host health remains uncovered. Here, we showed that the interaction between intestinal fungi and bacteria shaped lung inflammation during infection.

Erratum: Lycorine hydrochloride inhibits melanoma cell proliferation, migration and invasion via down-regulating p21.

[This corrects the article on p. 1391 in vol. 11, PMID: 33948364.

Taxonomic notes on the genus Chevrolat, 1863 (Coleoptera, Cerambycidae), with one new synonym and four newly recorded species from China.

Pic, 1918 is redescribed. Four species, Holzschuh, 1992, Holzschuh, 2016, Holzschuh, 1991 and Holzschuh, 1992 are newly reported from China. A new synonymy, (Chevrolat, 1863) = Pic, 1949, .

Discovery of a polyketide carboxylate phytotoxin from a polyketide glycoside hybrid by β-glucosidase mediated ester bond hydrolysis.

Fungal phytotoxins cause significant harm to agricultural production or lead to plant diseases. Discovering new phytotoxins, dissecting their formation mechanism and understanding their action mode are important for controlling the harmful effects of fungal phytopathogens. In this study, a long-term unsolved cluster (polyketide synthase 16, PKS16 cluster) from species was thoroughly investigated and a series of new metabolites including both complex α-pyrone-polyketide glycosides and simple polyketide carboxylates were identified from .

New species of Chopard, 1929 and Qiu & Che, 2024 (Blattodea, Corydioidea, Corydiinae), with notes on their female genitalia.

Two new species of ( Han, Che & Wang, and Han, Che & Wang, ) and six new species of ( Han, Che & Wang, , Han, Che & Wang, , Han, Che & Wang, , Han, Che & Wang, , Han, Che & Wang, , and Han, Che & Wang, ) are described and illustrated. The female external genitalia and spermathecae of these two genera are reported and the role of these characters in species delimitation is discussed.

 gen. nov., a new genus of Cicurinidae (Arachnida, Araneae) from Xizang, China, with description of two new species.

Wang & Zhang, , a new genus belonging to Cicurinidae, is established, and two new species are described, Wang & Zhang, (♂♀, type species) and Wang & Zhang, (♂♀), from Xizang, China. Detailed descriptions of somatic features and genital characteristics, photos of the habitus, photos and drawings of the copulatory organs, and a distribution map are provided.

[Synergistic effect and compatibility structure of active anti-inflammatory ingredients from Lamiophlomis rotata based on network pharmacology and component structure theory].

The synergistic effect and compatibility structure of active anti-inflammatory ingredients(iridoid glycosides: shanzhiside methylester and 8-O-acetylshanzhiside methyl ester, flavonoid glycoside: luteoloside, and phenylethanoid glycoside: forsythoside B) from Lamiophlomis rotata were explored based on network pharmacology and component structure theory. In network pharmacology, CTD, SwisseTargetPrediction, and PharmMapper databases were used to collect and screen the targets of all active ingredients. The inflammation-related targets were obtained from CTD and GeneCards databases.

[Mechanism of Yupingfeng Powder on hepatic insulin resistance in type 2 diabetes mellitus rats by regulating IRS/PI3K/Akt pathway].

Based on the insulin receptor substrate(IRS)/phosphoinositide 3-kinase(PI3K)/protein kinase B(Akt) pathway, the intervention effect of Yupingfeng Powder on type 2 diabetes mellitus(T2DM) rats was studied, and the potential mechanism of improving T2DM hepatic insulin resistance was explored. A T2DM rat model was established by feeding with high-fat and high-sugar feed combined with intraperitoneal injection of streptozotocin. Successfully modeled rats were selected and divided into a model group, a positive control group(MET), and a Yupingfeng Powder group.

Seven new species of the subgenus Malloch (Diptera, Lauxaniidae, ) from Jiangjin District, southwestern Chongqing, China.

Seven new species of the subgenus Homoneura are described, Homoneura (Homoneura) biconica Chen & Li, , Homoneura (Homoneura) dilatata Chen & Li, , Homoneura (Homoneura) jiangjinensis Chen & Li, , Homoneura (Homoneura) microtricha Chen & Li, , Homoneura (Homoneura) multiseta Chen & Li, , Homoneura (Homoneura) serrulata Chen & Li, , Homoneura (Homoneura) simianshana Chen & Li, , which were collected from Jiangjin District, southwestern Chongqing, China and are assigned to the group. A key to all of the 53 species of this species group in China is presented.

High-efficiency color-tunable ultralong room-temperature phosphorescence from organic-inorganic metal halides synergistic inter/intramolecular interactions.

Materials exhibiting highly efficient, ultralong and multicolor-tunable room-temperature phosphorescence (RTP) are of practical importance for emerging applications. However, these are still very scarce and remain a formidable challenge. Herein, using precise structure design, several novel organic-inorganic metal-halide hybrids with efficient and ultralong RTP have been developed based on an identical organic cation (A).

Asymmetric three-component Tsuji-Trost allylation reaction enabled by chiral aldehyde/palladium combined catalysis.

Despite the long-standing exploration of the catalytic asymmetric Tsuji-Trost allylation reaction since the mid-20th century, most reported instances have adhered to a two-component approach. Here, we present a remarkably efficient three-component asymmetric allylation reaction enabled by the collaborative action of chiral aldehyde and palladium. A diverse array of NH-unprotected amino acid esters, aryl or alkenyl iodides, and allyl alcohol esters exhibit robust participation in this reaction, resulting in the synthesis of structurally diverse non-proteinogenic α-amino acid esters with favorable experimental outcomes.

The utilization of quantum dot labeling as a burgeoning technique in the field of biological imaging.

Quantum dots (QDs), with their unique optical and physical properties, have revolutionized the field of biological imaging, providing researchers with tools to explore cellular processes and molecular interactions in unprecedented detail. This review explores the diverse properties of QDs, emphasizing their application in biological imaging and addressing both their advantages and challenges. We discuss the developments in QD technology that have facilitated their integration into bioimaging, highlighting the role of surface modifications in enhancing their biocompatibility and functionality.