Adhesive and Conductive Hydrogels for the Treatment of Myocardial Infarction.

Myocardial infarction (MI) is a leading cause of mortality among cardiovascular diseases. Following MI, the damaged myocardium is progressively being replaced by fibrous scar tissue, which exhibits poor electrical conductivity, ultimately resulting in arrhythmias and adverse cardiac remodeling. Due to their extracellular matrix-like structure and excellent biocompatibility, hydrogels are emerging as a focal point in cardiac tissue engineering.

Association between the immune-inflammation indicators and osteoarthritis - NHANES 1999-2018.

Background: Investigate the link between systemic immune-inflammatory index (SII) and Systemic Immune Response Index (SIRI) with osteoarthritis (OA) using National Health and Nutrition Examination Survey (NHANES) data (1999-2018).

Methods: Extracted NHANES data (1999-2018) and selected a study population based on demographic, examination, and laboratory data. Calculated SII (platelet count ​× ​neutrophil count/lymphocyte count) and SIRI (neutrophil count ​× ​monocyte count/lymphocyte count).

Impact of intermediate-dose tertiary prophylaxis on quality of life and psychological aspects of adult patients with severe/moderate hemophilia A.

Objectives: Whether intermediate-dose tertiary prophylaxis can improve quality of life and psychological health in adults with severe/moderate hemophilia A has not been determined. This research aims to explore the impact of intermediate-dose tertiary prophylaxis with recombinant human FVIII (rhFVIII) on quality of life, anxiety and depression in such individuals transitioned from on-demand treatment.

Methods: This retrospective analysis collected data from July 2019 to July 2022.

Nano-polymeric platinum activates PAR2 gene editing to suppress tumor metastasis.

Metastasis as the hallmark of cancer preferentially contributes to tumor recurrence and therapy resistance, aggrandizing the lethality of patients with cancer. Despite their robust suppressions of tumor progression, chemotherapeutics failed to attenuate cancer cell migration and even triggered pro-metastatic effects. In parallel, protease-activated receptor 2 (PAR2), a member of the G protein-coupled receptor subfamily, actively participates in cancer metastasis via multiple signal transduction pathways.

Room-Temperature CsPbI-Quantum-Dot Reinforced Solid-State Li-Polymer Battery.

A novel polymer electrolyte based on CsPbI quantum dots (QDs) reinforced polyacrylonitrile (PAN), named as PIL, is exploited to address the low room-temperature (RT) ion conductivity and poor interfacial compatibility of polymer solid-state electrolytes. After optimizing the content of CsPbI QDs, RT ion conductivity of PIL largely increased from 0.077 to 0.

Characterizing Surface Deformation of the Earthquake-Induced Daguangbao Landslide by Combining Satellite- and Ground-Based InSAR.

The Daguangbao landslide (DGBL), triggered by the 2008 Wenchuan earthquake, is a rare instance of super-giant landslides globally. The post-earthquake evolution of the DGBL has garnered significant attention in recent years; however, its deformation patterns remain poorly characterized owing to the complex local topography. In this study, we present the first observations of the surface dynamics of DGBL by integrating satellite- and ground-based InSAR data complemented by kinematic interpretation using a LiDAR-derived Digital Surface Model (DSM).

A Method for Determining the Fracture Toughness of Shotcrete Materials Subjected to Freeze-Thaw Cycles.

Defects can be introduced into shotcrete materials after a few freeze-thaw cycles, which has a significant influence on the fracture performance of shotcrete. In this study, a series of shotcrete specimens with varying sizes, geometries, and initial crack lengths were prepared to investigate the fracture properties of notched shotcrete under freeze-thaw conditions. Considering the effects of specimen boundaries and material microstructure, a linear closed-form solution was proposed to determine the fracture toughness of frost-damaged shotcrete.

The relationship between psychological resilience, perceived social support, acceptance of illness and mindfulness in patients with hepatolenticular degeneration.

To investigates the current status of mindfulness in patients with Wilson's disease (WD) and to explore the effects of psychological resilience, perceived social support, and acceptance of illness on their mindfulness. By using the convenient sampling method, 136 patients with WD were selected from May 2019 to January 2023 in 12 tertiary hospitals in Chengdu. General information questionnaire, five facet mindfulness scale, resilience scale, acceptance of illness and perceived social support scale were used to conduct the investigation.

Comparative analysis of general and regional anesthesia applications in geriatric hip fracture surgery.

Background: This study compares the outcomes of general anesthesia (GA) and regional anesthesia (RA) in geriatric hip fracture surgery to determine optimal anesthesia strategies for this population.

Methods: A comprehensive literature review was conducted, analyzing studies comparing GA and RA in elderly patients undergoing hip fracture surgery. Studies encompassed various designs, including randomized controlled trials, cohort studies, and meta-analyses.

Parental expectations and adolescents' happiness: the role of self-efficacy and connectedness.

Background: A happy adolescent may live a healthy and successful life. This study focused on parental expectations in the Chinese cultural context and investigated whether and under what conditions adolescents' perceived parental expectations are associated with their happiness, the affective component of subjective well-being.

Sample And Methods: This cross-sectional study included a sample of 1510 Chinese adolescents; the average age of the adolescents was 12.

Diterpenoid alkaloids from the roots of Aconitum bulbilliferum.

The phytochemistry study of Aconitum bulbilliferum Hand.-Mazz. is firstly reported.

Mineral-dependent release, migration and enrichment of toxic elements during black shale weathering: An integrated study from profile scale to mineral scale.

Chemical weathering of lithologies with high geochemical backgrounds such as black shale has been proposed to be a critical source for toxic elements in soil and water systems. However, mechanisms controlling the release, migration and enrichment of toxic elements during black shale weathering are poorly understood. This study utilized a suite of micro analytical techniques such as TESCAN integrated mineral analyzer (TIMA), scanning electron microscopy-energy dispersive X-ray spectroscopy (SEM-EDS), X-ray photoelectron spectroscopy (XPS) and electron micro-probe analysis (EMPA) to elucidate the intimate relationship between mineralogical transformations and elemental behaviors from profile scale to mineral scale.

Molecular composition of hydroxyl radical-resistant organics in municipal solid waste leachate.

Although hydroxyl radicals (OH) degrade organic pollutants nonselectively, their mineralization rate during the treatment of waste leachate biological treatment effluent (BTL) using Fenton or Fenton-like systems is not high, and the reason is unknown. In this study, we investigated three typical Fenton-like systems that act on dissolved organic matter (DOM) in BTL. We analyzed the molecular composition of DOM resistant to OH, using ultrahigh resolution mass spectrometry.

Deciphering the driving mechanism of microbial community for rapid stabilization and lignocellulose degradation during waste semi-aerobic bioreactor landfilling with multifunctional microbial inoculum.

Owing to the massive refractory lignocellulose and leachate-organic loads, the stabilization of municipal solid waste (MSW) landfill is often prolonged, resulting in environmental burdens. Herein, various assembled multifunctional microbial inoculums (MMIs) were introduced into the semi-aerobic bioreactor landfill (SABL) to investigate the bioaugmentation impacts. Compared to control (CK) and other MMIs treatments (G1-G3), LD + LT + DM inoculation (G4) significantly increased volatile solids degradation (9.

Macrophage Membrane-Cloaked ROS-Responsive Albumin Nanoplatforms for Targeted Delivery of Curcumin to Alleviate Acute Liver Injury.

Developing low-toxicity, high-efficacy, and fast-acting strategies to manage acute liver injury (ALI) is critical due to its rapid progression and potential for severe outcomes. Curcumin (CUR) has shown promise in ALI therapy due to its ability to modulate the inflammatory microenvironment by scavenging reactive oxygen species (ROS). Nevertheless, CUR is highly hydrophobic limiting its bioavailability and effective in vivo transport, which hinders its further application.

Chitosan/Alginate-Based Hydrogel Loaded With VE-Cadherin/FGF as Scaffolds for Wound Repair in Different Degrees of Skin Burns.

Burns are complex traumatic injuries that lead to severe physical and psychological problems due to the prolonged healing period and resulting physical scars. Owing to their versatility, hydrogels can be loaded with various functional factors, making them promising wound dressings. However, many hydrogel dressings cannot support cell survival for a long time, thereby delaying the process of tissue repair.

Semantic alignment: A measure to quantify the degree of semantic equivalence for English-Chinese translation equivalents based on distributional semantics.

The degree of semantic equivalence of translation pairs is typically measured by asking bilinguals to rate the semantic similarity of them or comparing the number and meaning of dictionary entries. Such measures are subjective, labor-intensive, and unable to capture the fine-grained variation in the degree of semantic equivalence. Thompson et al.

FeMOFs/CO loading reduces NETosis and macrophage inflammatory response in PLA based cardiovascular stent materials.

Modification of polylactic acid (PLA) is a promising strategy for the next generation of bioresorbable vascular stent biomaterials. With this focus, FeMOFs nanoparticles was incorporated in PLA, and then post loading of carbon monoxide (CO) was performed by pressurization. It showed FeMOFs incorporation increased hydrophilicity of the surface and CO loading, and CO release was sustained at least for 3 days.

Experimental demonstration of 8190-km long-haul semiconductor-laser chaos synchronization induced by digital optical communication signal.

Common-signal-induced synchronization of semiconductor lasers have promising applications in physical-layer secure transmission with high speed and compatibility with the current fiber communication. Here, we propose an ultra-long-distance laser synchronization scheme by utilizing random digital optical communication signal as the common drive signal. By utilizing the long-haul optical coherent communication techniques, high-fidelity fiber transmission of the digital drive can be achieved and thus ultra-long-distance synchronization is expected.

The association of serum total bile acids and deep venous thrombosis.

Background And Aim: Bile acid metabolism plays a crucial role in maintaining the delicate balance between coagulation and anticoagulation processes. However, there is a paucity of research exploring the relationship between serum total bile acids (TBA) levels and the risk of deep venous thrombosis (DVT) in Chinese individuals. The primary objective of this study is to investigate the association between TBA levels and DVT occurrence in this population.

Effects of transurethral 0bipolar plasma prostatectomy on urodynamics and sexual function in patients with prostatic hyperplasia.

This was an original article, and the objective of this study was to investigate the effects of bipolar transurethral plasma kinetic prostatectomy (TUPKP) on urodynamics and sexual function in benign prostatic hyperplasia (BPH) patients. One hundred and four BPH patients were divided into a control group and an intervention group. The control group received transurethral resection of prostate, while the intervention group received TUKEP.

A Registration Method Based on Ordered Point Clouds for Key Components of Trains.

Point cloud registration is pivotal across various applications, yet traditional methods rely on unordered point clouds, leading to significant challenges in terms of computational complexity and feature richness. These methods often use k-nearest neighbors (KNN) or neighborhood ball queries to access local neighborhood information, which is not only computationally intensive but also confines the analysis within the object's boundary, making it difficult to determine if points are precisely on the boundary using local features alone. This indicates a lack of sufficient local feature richness.

Layered Composites for High Tan Delta Plateau over Wide Temperature Range.

Tan Delta reflects the viscoelastic behavior of materials, particularly polymers. In most cases, a high Tan Delta value is associated with transitions (such as glass transition or melting), enabling effective damping properties near these temperature ranges. However, achieving a high Tan Delta over a broad temperature range is challenging, particularly for engineering applications that involve significant temperature fluctuations.

Influence of Bonding Temperature on Microstructure and Mechanical Properties of AZ31/Zn/Sn/5083 Diffusion Joint.

Diffusion bonding with an interlayer is considered an effective means of obtaining Mg/Al dissimilar alloy joints. However, at low temperatures, it is often impossible to simultaneously achieve joints between the interlayer and Mg/Al under the same bonding parameters. For this reason, the interlayer is usually prefabricated on the substrate, followed by conducting diffusion bonding.