Current FDA-Approved Therapies for High-Grade Malignant Gliomas.

The standard of care (SOC) for high-grade gliomas (HGG) is maximally safe surgical resection, followed by concurrent radiation therapy (RT) and temozolomide (TMZ) for 6 weeks, then adjuvant TMZ for 6 months. Before this SOC was established, glioblastoma (GBM) patients typically lived for less than one year after diagnosis, and no adjuvant chemotherapy had demonstrated significant survival benefits compared with radiation alone. In 2005, the Stupp et al.

Heating capacity of rebound shortwave diathermy and moist hot packs at superficial depths.

Context: The effectiveness of a new continuous diathermy unit, ReBound, as a heating modality is unknown.

Objective: To compare the effects of ReBound diathermy with silicate-gel moist hot packs on tissue temperature in the human triceps surae muscle.

Design: Crossover study.