2 results match your criteria: "Southern Medical University Stomatological Hospital[Affiliation]"

Periodontitis is one of the major global public health problems associated with the occurrence and development of diverse systemic diseases, especially acquired immune deficiency syndrome (AIDS), necessitating further research and clinical attention. The persistence of HIV-1 latency poses a significant challenge to the attainment of a functional cure for AIDS, despite the introduction of highly active antiretroviral therapy (HAART). A similar mechanistic basis between periodontitis and HIV-1 latency has been revealed by many studies, suggesting possible mechanisms whereby periodontitis and HIV-1 latency may mutually influence each other.

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[Effect of Lipoteichoic Acid Synthesis-Related Gene on Acid Tolerance of Highly Cariogenic Strains of ].

Sichuan Da Xue Xue Bao Yi Xue Ban

March 2022

Fujian Provincial Key Laboratory of Oral Diseases, Fujian Provincial Engineering Research Center of Oral Biomaterial, Key Lab of Stomatology for Higher Education Institutions in Fujian Province, and Cariology and Endodontics Department Ⅰ, School/Hospital of Stomatology, Fujian Medical University, Fuzhou 350000, China.

Objective: To study the role and possible mechanism of in the acid tolerance of 593 (593), and to provide a theoretical basis for the ecological prevention and control of dental caries by constructing the gene deletion strain of 593 (593-Δ).

Methods: 1) 593-Δ was constructed by homologous recombination. 2) The growth curve of 593 and 593-Δ under different pH culture conditions was drawn by the automatic growth curve analyzer to compare their acid tolerance.

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