1 results match your criteria: "Southern Medical University Beijing 100007[Affiliation]"
T3 inhibits the calcification of vascular smooth muscle cells and the potential mechanism.
Am J Transl Res
November 2016
Department of Neonatology, Affiliated Bayi Children's Hospital, Clinical Medical College in PLA Army General Hospital, Southern Medical University Beijing 100007, China.
Objective: This study aimed to investigate the potential molecular mechanism underlying the T3 induced vascular calcification and phenotype transformation of vascular smooth muscle cells (VSMCs).
Methods: Rat thoracic aortic smooth muscle cells (A7r5) were cultured in vitro and randomly assigned into normal control group, calcification group, T3 group and inhibitor group.
Results: When compared with normal control group, the osteocalcin content, ALP activity, Osterix and Runx2 mRNA expression and OPN protein expression increased significantly (<0.