8 results match your criteria: "Southern Medical University (Dongguan People's Hospital) Dongguan[Affiliation]"
Dynamic mRNA network profiles in macrophages challenged with lipopolysaccharide.
Am J Transl Res
May 2024
Guangdong Provincial Key Laboratory of Proteomics, State Key Laboratory of Organ Failure Research, Department of Pathophysiology, School of Basic Medical Sciences, Southern Medical University Guangzhou 510515, Guangdong, China.
Article Synopsis
- The study aimed to explore how macrophages react at the gene level during inflammation triggered by lipopolysaccharide (LPS) using RNA sequencing.
- Researchers identified 2,512 differentially expressed genes, with notable early inflammatory responses occurring at 1 and 3 hours after LPS treatment, revealing important patterns over time.
- Key findings included a set of 78 consistently affected genes and highlighted the role of ribosomes in managing the inflammatory response, which could guide future research on inflammation mechanisms.
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
Am J Cancer Res
April 2024
Department of Hepatobiliary, Pancreatic and Splenic Surgery, The Tenth Affiliated Hospital, Southern Medical University (Dongguan People's Hospital) Dongguan, Guangdong, China.
Recent studies have indicated that the dual-specificity phosphatases (DUSP) family may play a role in the advancement of pancreatic cancer. Exploring the role of the DUSP family in pancreatic cancer development and discovering novel therapeutic targets are crucial for pancreatic cancer therapy. A critical subset of 20 genes exhibiting differential expression was identified, with particular emphasis on four key genes: DUSP10, PTP4A2, SSH3, and CDKN3 by multivariate Cox proportional hazards analysis.
View Article and Find Full Text PDFEffects of Lactobacillus acidophilus and L. reuteri on bone mass and gut microbiota in ovariectomized mice.
Cell Mol Biol (Noisy-le-grand)
September 2023
Department of Orthopedics, Affiliated Dongguan Hospital, Southern Medical University (Dongguan People's Hospital) & Dongguan Key Laboratory of Basic, Clinical and Digital Research on Common Orthopedic Diseases, Dongguan,523000, China.
Lactobacillus acidophilus is widely used as a food additive or medication in our daily lives. The objective of this study was to investigate the effects of L. acidophilus and L.
View Article and Find Full Text PDFImaging findings of succinate dehydrogenase-deficient renal cell carcinoma.
Clin Case Rep
August 2023
Department of Ultrasound, Affiliated Dongguan Hospital, Southern Medical University Dongguan People's Hospital Dongguan China.
Key Clinical Message: A 50-year-old man with a mass located in the left kidney was described by multimodal images, including ultrasonography, computed tomography, and magnetic resonance imaging. After surgical resection of the mass, pathological examination confirmed succinate dehydrogenase-deficient renal cell carcinoma.
Abstract: Succinate dehydrogenase-deficient renal cell carcinoma (SDH-deficient RCC) is a malignant tumor in the kidney associated with the loss of mitochondrial enzyme II.
The conversion of biomass materials into high value-added chemicals is receiving more and more attention. Herein, biomass olive leaves are converted into carbonized polymer dots (CPDs) through a simple hydrothermal reaction. The CPDs show near infrared light emission properties, and the absolute quantum yield reaches a record breaking value of 71.
View Article and Find Full Text PDFArticle Synopsis
- A high-salt diet in mice leads to cognitive issues and reduced synaptic protein levels due to changes in gut microbiota and short-chain fatty acid production.
- Mice with gut microbiota from high-salt diet-fed mice show impaired memory and synapse function when placed on a regular diet.
- Treatment with butyrate, a short-chain fatty acid, helps improve memory impairments in mice that were on a high-salt diet, highlighting the gut microbiome's significant role in cognitive health.
Clinical value of the platelet and inflammatory factor activation in vascular endothelial injury in essential hypertension.
Clin Hemorheol Microcirc
March 2023
Department of Geriatrics, Nanfang Hospital. Guangzhou, Guangdong, China.
Objective: To investigate the clinical value of platelet and inflammatory factor activation in vascular endothelial injury in hypertension.
Methods: A total of 120 hypertension patients diagnosed in our hospital from December 2019 to June 2021 were enrolled as study objects (Hypertension group); besides, another cohort of 60 healthy people undergoing physical examination at the same period were recruited as the controls (Control group). Next, the baseline clinical characteristics of subjects in the two groups were recorded and compared.
Imaging findings of the primary mucoepidermoid carcinoma of the breast.
Clin Case Rep
February 2022
Department of Ultrasound Affiliated Dongguan Hospital, Southern Medical University Dongguan People's Hospital Dongguan China.
Mucoepidermoid carcinoma (MEC) is an invasive tumor that has been reported in many organs, such as the salivary glands, lungs, esophagus, and thymus; however, it rarely affects the breast. Here, we report a case of primary breast MEC with imaging, including mammography, ultrasonography, and magnetic resonance imaging.
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