5 results match your criteria: "South-Ural Scientific Centre[Affiliation]"

Article Synopsis
  • Erythroblastic islands in bone marrow are essential for the production of red blood cells (erythropoiesis) and consist of specialized cells called erythrokariocytes and macrophages.
  • The functional status of these cells was analyzed by measuring ribonucleoprotein content using the Brashe reaction.
  • Conditions like acute blood loss and post-transfusion polycythemia increase ribonucleoprotein levels in both erythrokariocytes and macrophages in the bone marrow of rats.
View Article and Find Full Text PDF

[Effect of erythrocytes from intact, polycythemic, and anemic rats on erythropoiesis in erythroblastic island culture].

Ross Fiziol Zh Im I M Sechenova

January 2004

South-Ural Scientific Centre, Russian Acad. Med. Sci., 454092, Cheliabinsk, 64 Vorovskogo St., Russia.

Article Synopsis
  • The study examined how different stages of erythrocyte maturity and their quantities affect erythropoiesis in cultured erythroblastic islands.
  • It was found that both the amount and the maturity of erythrocytes have a dose-dependent and maturity-dependent inhibitory effect on the formation of erythroblastic islands.
  • Additionally, erythrocytes from polycythemic rats were shown to inhibit the maturation and formation of these islands more effectively compared to erythrocytes from normal or anemic rats.
View Article and Find Full Text PDF

[Activity of nucleolar organizers in central macrophage culture of bone marrow erythroblastic islands].

Ross Fiziol Zh Im I M Sechenova

September 2003

South-Ural Scientific Centre, Russian Academy of Medical Sciences, 454092, Chelyabinsk, Russia.

The erythroblastic islands of the bone marrow are morphofunctional units of erythropoiesis. In this work the functional state of erythroblastic islands' cells of the bone marrow, for the first time, was defined by the estimation of the activity of the nucleolar organizers of central macrophages in the erythroblastic islands, cultivated during 24 and 48 hours with the presence of various doses of erythropoietin. The findings indicated that the increase in doses of erythropoietin was accompanied by the corresponding increase of the activity of nucleolar organizers in central macrophages of erythroblastic islands.

View Article and Find Full Text PDF

[The effect of humoral factors on phagocytic activity of central macrophages in the erythroblast islet culture].

Ross Fiziol Zh Im I M Sechenova

September 2002

South-Ural Scientific Centre, Russian Acad. Med. Sci., 454092, Cheliabinsk, 64 Vorovskogo St., Russia.

A 24-hour cultivation of erythroblast islets (El) in presence of erythropoietin (EP) and macrophage colony stimulating factor (MCSF) led to a concentration-dependent enhancement of phagocytic activity (PA) of the El's "central" macrophages. The latter phenomenon was revealed in "mature" El classes only. The PA of "central" macrophages in "proliferating" El appeared to be affected neither by EP, nor by MCSF.

View Article and Find Full Text PDF

[Activity of the nucleolar organizers in cultured cells from the bone marrow erythroblastic islets].

Ross Fiziol Zh Im I M Sechenova

September 2002

South-Ural Scientific Centre, Russian Acad. Med. Sci., 454092, Cheliabinsk, 64 Vorovskogo St., Russia.

The erythroblast islands of the bone marrow are the morphofunctional units of erythropoiesis. In this work, the functional state of erythroblast islands' cells of the bone marrow for the first time was defined by estimation of the activity of the nucleolar organizers of erythroid cells in the erythroblast islands cultivated during 24 and 48 hours in presence of various doses of erythropoietin. The findings indicated that an increase in doses of erythropoietin was accompanied by a corresponding increase of the activity of nucleolar organizers in erythrokaryocytes of erythroblast islands.

View Article and Find Full Text PDF