127 results match your criteria: "South-Eastern Finland University of Applied Sciences[Affiliation]"

Physical activity guidelines targeting different populations with and without chronic diseases or disabilities are required to meet the diverse functional and physiological needs experienced by different subgroups of people to achieve optimal health benefits. As the importance of physical activity guidelines in promoting optimal health and well-being becomes increasingly recognised, there is a critical need for their systematic evaluation to ensure they remain effective, applicable and aligned with evolving health needs and scientific insights. This study aims to systematically review, critically evaluate, and compare global physical activity and sedentary behaviour guidelines on frequency, intensity, time, and type of exercise for adults, pregnant and postpartum women, and people living with chronic conditions and/or disabilities.

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Background: Chemical, biological, radiological, nuclear, and explosive (CBRNE) incidents present rare and complex challenges for Emergency Medical Services (EMS), necessitating effective incident command to manage occupational and patient safety risks. EMS incident commanders must make quick decisions under pressure, coordinating medical responses and ensuring personnel's safety. This study examined the perceived competence requirements of Finnish EMS field supervisors in managing C and E incidents.

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Aim: To describe how nursing staff assess their superiors' destructive leadership and nurse leaders' structural empowerment. A further aim is to examine the associations between destructive leadership and staff outcomes and how nurse leaders' structural empowerment moderates these associations.

Design: A cross-sectional study.

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In this study, we explored the structural and chemical modifications of cellulose fibres subjected to chemical and mechanical treatments through an innovative analytical approach. We employed photoacoustic spectroscopy (PAS) and reversed double-beam photoacoustic spectroscopy (RDB-PAS) to examine the morphological changes and the chemical integrity of the treated fibres. The methodology provided enhanced sensitivity and specificity in detecting subtle alterations in the treated cellulose structure.

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RNA sequencing analysis reveals distinct gene expression patterns in infrapatellar fat pads of patients with end-stage osteoarthritis or rheumatoid arthritis.

Biochim Biophys Acta Mol Cell Biol Lipids

January 2025

Institute of Biomedicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland. Electronic address:

Article Synopsis
  • Osteoarthritis (OA) and rheumatoid arthritis (RA) are both inflammatory joint diseases with overlapping symptoms but distinct causes, potentially linked to adipose tissue like the infrapatellar fat pad (IFP).
  • The study aimed to identify key genes and pathways in IFPs of OA and RA patients through RNA sequencing, ultimately looking to enhance diagnostics and develop personalized treatment options.
  • Findings revealed significant differences in gene expression between OA and RA, highlighting specific metabolic pathways and suggesting that IFP plays a role in inflammation and cartilage degradation, potentially offering new targets for diagnosis and therapy.
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Background: Overweight and obesity are global health concerns, especially significant for older adults at higher risk for chronic diseases. The transition to retirement, altering daily routines, highlights the need for adequate weight management support. Since obesity is a challenging topic in healthcare and socioeconomic inequalities exist in access and utilization, we examined how retired individuals with obesity and low or high education describe their experiences of unmet needs, mismatches, and successes within the healthcare service system for weight management.

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Course and Predictors of Adult Spinal Sagittal Disorders: A 10-year Prospective Case Series.

Spine (Phila Pa 1976)

October 2024

Department of Orthopaedics and Traumatology, Hospital Nova, Wellbeing services county of Central Finland.

Article Synopsis
  • The study aimed to track the progression of adult spinal deformity (ASD) over a decade, focusing on factors that affect spinal alignment.
  • It involved analyzing full spine radiographs of 204 participants, showing a significant overall deterioration in spinal condition, with only 13% of participants experiencing improvement.
  • Key predictors for changes in spinal alignment included low scores on self-assessment questionnaires related to function and severe pelvic tilt, emphasizing the need for personalized treatment approaches based on individual risk factors.
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Aim: To identify and describe evidence from original studies on the contextual factors, dimensions, and outcomes of decent and precarious work among nursing and care workers.

Design: This is a mixed-methods systematic review.

Data Sources: The Scopus, Web of Science, PubMed, CINAHL, PsycINFO and SocINDEX databases were searched on January 11, 2024.

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Article Synopsis
  • The study investigates how different movement behaviors (like physical activity and sedentary time) affect cardiometabolic health in women with and without polycystic ovary syndrome (PCOS).
  • It found no overall differences in daily movement patterns between the groups, but reducing sedentary behavior (SB) while increasing moderate-to-vigorous physical activity (MVPA) improved health markers for women without PCOS, while women with PCOS only showed benefits from substituting SB with MVPA.
  • The research involved a large cohort study from Northern Finland, analyzing data from 5889 women with follow-ups at ages 31 and 46, focusing on physical activity levels and cardiometabolic health indicators.
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Background: Wrist-worn data from commercially available devices has potential to characterize sedentary time for research and for clinical and public health applications. We propose a model that utilizes heart rate in addition to step count data to estimate the proportion of time spent being sedentary and the usual length of sedentary bouts.

Methods: We developed and trained two Hidden semi-Markov models, STEPHEN (STEP and Heart ENcoder) and STEPCODE (STEP enCODEr; a steps-only based model) using consumer-grade Fitbit device data from participants under free living conditions, and validated model performance using two external datasets.

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"Balancing work and movement": barriers and enablers for being physically active at Indian workplaces - findings from SMART STEP trial.

Int J Behav Nutr Phys Act

September 2024

Department of Community Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.

Background: Non-communicable diseases are rising rapidly in low- and middle-income countries, leading to increased morbidity and mortality. Reducing sedentary behavior (SB) and increasing physical activity (PA) offer numerous health benefits. Workplaces provide an ideal setting for promoting SB/PA interventions; however, understanding the barriers and enablers is crucial for optimizing these interventions in workplace environments.

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Purpose: We compared the performance of SARC-F, SARC-CalF, calf circumference (CC), and body mass index (BMI)-adjusted CC for sarcopenia case-finding in community-dwelling older adults.

Methods: Data of Finnish participants (women/men n = 192/36, mean age (SD) of 76.9 (4.

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Aim: To explore Finnish paramedics' perceptions of work-related performance expectations in relation to work experience, and understand how organizational socialization contributes to understanding paramedics' performance expectations.

Design: A qualitative design with a deductive-inductive approach utilizing a social constructivist framework. The organizational socialization framework by Wanberg was used as the theoretical basis.

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Article Synopsis
  • A systematic review and meta-analysis was conducted to explore the causal relationships between genetically determined sedentary behaviors and various health outcomes, looking at data from 31 MR studies.
  • The analysis identified 47 significant causal associations, with increased leisure TV watching linked to higher risks of heart diseases and type 2 diabetes, while leisure computer use showed protective effects against certain health conditions like arthritis and Alzheimer's.
  • The study concludes that different sedentary behaviors have unique effects on health, emphasizing the need for targeted interventions that not only reduce sedentary time but also encourage healthier sedentary activities.
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Background: The dynamic and challenging work environment of the prehospital emergency care settings creates many challenges for paramedics. Previous studies have examined adverse events and patient safety activities, but studies focusing on paramedics' perspectives of factors contributing to human error are lacking. In this study, we investigated paramedics' opinions of the factors contributing to human errors.

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Introduction: Muscle activation during interruptions to prolonged sedentary time is a hypothesized mechanism underlying observed cardiometabolic benefits. We examined associations of quadriceps and hamstring muscle activity patterns with cardiometabolic risk markers and how these patterns varied between different sitting-interruption countermeasures.

Methods: Electromyographic (EMG) data (shorts) were gathered for 1 to 2 d from healthy adults in a free-living study ( n = 172, age 40.

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Background: As first responders, paramedics are an extremely important part of the care chain. COVID-19 significantly impacted their working circumstances. We examined, according to the experiences and observations of paramedics, (1) what kinds of emotions the Emergency Medical Service (EMS) personnel experienced in their new working circumstances, and (2) what work-related factors became resources for the well-being of EMS personnel during the initial months of the COVID-19 pandemic.

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Article Synopsis
  • The inflammatory tumor microenvironment (TME) significantly contributes to cancer progression, particularly in prostate cancer.
  • Tumor-associated macrophages (especially M1, pro-inflammatory types) promote cancer stemness while suppressing androgen response in prostate cancer cells.
  • The study suggests that M1 macrophages do this by releasing factors that activate the NFκB signaling pathway, leading to increased expression of cancer stem cell markers like NANOG and KLF4.
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Introduction: The purpose of this study was to investigate the creation, implementation, and harmonisation of medical Standard Operating Procedures (SOP) in Finnish Helicopter Emergency Medical Services (HEMS). The research questions are: (1) What factors influence the creation and implementation of medical SOPs for Finnish HEMS units? and (2) What can be done to harmonise the medical SOPs of Finnish HEMS units?

Methods: The research was conducted as a qualitative interview study with HEMS physicians who worked full-time in Finnish HEMS units or had worked in HEMS for more than five years. Three HEMS physicians from each of the six HEMS units in Finland participated in the study (n = 18).

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  • The study aimed to understand how vitamin D affects the immune system by supplementing 25 healthy individuals with a high dose of vitamin D (80,000 IU) and analyzing their blood.
  • Researchers found 452 genes in the participants' white blood cells that significantly responded to vitamin D, with 138 confirmed as direct targets of the active form of vitamin D.
  • The study categorized participants into high, mid, and low responders based on their genetic expression changes, identifying HLA-C as a key gene associated with varying vitamin D responsiveness.
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Aim: To investigate the effects of psychological contract breach and psychological safety on health and well-being outcomes among nurses.

Design: A cross-sectional study.

Methods: Data were gathered from members of the Finnish social and healthcare workers' trade union (n = 4575) in February 2023.

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Background: High levels of sedentary behavior in workplaces are currently recognized as an independent risk factor for cognitive dysfunction and poor mental health. However, sedentary patterns vary between workdays and non-workdays, which may influence cognitive functions.

Objective: The present study aimed to quantify and compare work and nonwork device-measured sedentary time (ST) and its association with cognitive function in Indian office workers.

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Article Synopsis
  • Obesity is linked to inflammation in adipose tissue (AT) and the secretion of extracellular vesicles (EVs), which play a role in metabolic disorders; however, the exact mechanisms are not fully understood.
  • Research examined EVs from human adipocytes and AT in subjects undergoing bariatric surgery, using various advanced analytical techniques to understand the characteristics and behaviors of these EVs in response to different treatments.
  • Findings indicated that mature adipocytes release more EVs than preadipocytes, with inflammatory stimuli further enhancing EV secretion, particularly from visceral AT; this suggests a connection between increased EV release, AT expansion, and inflammation in obesity.
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Objectives: Since Helicopter Emergency Medical Services (HEMS) is an expensive resource in terms of unit price compared to ground-based Emergency Medical Service (EMS), it is important to further investigate which methods would allow for the optimization of these services. The aim of this study was to evaluate the cost-effectiveness of physician-staffed HEMS compared to ground-based EMS in developed scenarios with improvements in triage, aviation performance, and the inclusion of ischemic stroke patients.

Methods: Incremental cost-effectiveness ratio (ICER) was assessed by comparing health outcomes and costs of HEMS versus ground-based EMS across six different scenarios.

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