Linear IgA disease with haemorrhagic pompholyx and dapsone-induced neutropenia.

A case of haemorrhagic pompholyx occurring in a 29-year-old man with linear IgA disease is described. There were several features in our patient that are usually seen in chronic bullous disease of childhood. Treatment with dapsone cleared the eruption but induced a progressive yet reversible neutropenia.

Factors related to failure of structural bone grafts in acetabular reconstruction of total hip arthroplasty.

Structural bone grafts in acetabular reconstruction of total hip arthroplasty have come into more common usage with the increasing number of revision arthroplasties. The authors present the outcome of 40 bone grafts with follow-up periods of 2-8 years. Primary and revision arthroplasties with both cemented and noncemented fixation are included.

Computer control of anticoagulant dose for therapeutic management.

Objective: To improve the standard of managing anticoagulant treatment and provide a basis for therapeutic quality control.

Design: Implementation of a comprehensive computerised system for decision support.

Setting: Three anticoagulation clinics in South Warwickshire.