29 results match your criteria: "South Warwickshire Hospital[Affiliation]"

Background: Colonic mural thickening (MT) is often reported on standard CT examinations of the abdomen and pelvis. It often presents a dilemma for the clinician on whether any further evaluation is needed, especially in the absence of any set guidelines.

Objective: To evaluate the significance of colonic MT and to assess its correlation with colonoscopy.

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Perinatal depression involves interplay between individual chronic and acute disease burdens, biological and psychosocial environmental and behavioural factors. Here we explored the predictive potential of specific psycho-socio-demographic characteristics for antenatal and postpartum depression symptoms and contribution to severity scores on the Edinburgh Postnatal Depression Scale (EPDS) screening tool. We determined depression risk trajectories in 480 women that prospectively completed the EPDS during pregnancy (TP1) and postpartum (TP2).

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Objectives:   To assess the evidence and available literature on the clinical, pathogenetic, prognostic and therapeutic aspects of intracerebral haemorrhage.

Methods:   The most important manuscripts and reviews on the subject were considered. Information was collected from Medline, Embase & National Library of Medicine over the last 40 years up to Oct 2011.

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Drug induced parkinsonism is the second most common cause of parkinsonism in older people after idiopathic Parkinson's disease (PD). Risk factors for developing drug induced parkinsonism include: older age; female gender; dose and duration of treatment; type of agent used; cognitive impairment; acquired immunodeficiency syndrome (AIDS); tardive dyskinesia; and pre-existing extrapyramidal disorder. In most patients parkinsonism is reversible upon stopping the offending drug, though it may take several months to resolve fully and in some patients it may even persist.

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Tobacco smoke and the upper airway.

Clin Otolaryngol Allied Sci

December 2003

Department of Otorhinolaryngology/Head & Neck Surgery, South Warwickshire Hospital, Warwick, UK.

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Expression of heat-shock proteins (hsp) was analysed in the leukaemic cells of 12 patients with acute myeloid leukaemia (AML) and nine patients with chronic myeloid leukaemia (CML). Using monoclonal antibodies to hsp70, hsp90 and hsp60 (ML30, a mycobacterial antigen with homology to human hsp60), we measured hsp levels by flow cytometry of permeabilized cells. Mononuclear cells from 10 healthy volunteers were also examined.

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In the haemolytic uraemic syndrome (HUS), platelet microthrombi and deposition of fibrin in glomeruli may contribute to the development of renal failure. The balance of procoagulant and fibrinolytic activities in the renal vasculature may therefore have an important role. We measured plasminogen-activator inhibitor (PAI) activity in the plasma of 81 children with diarrhoea-associated (D+) HUS, and found elevated PAI activity in many patients.

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A method of intestinal anastomosis with a skin stapler has been used successfully in 39 patients to form 40 anastomoses. The method has been employed in elective and emergency surgery, in small and large intestine, for a variety of pathological conditions and in the presence of obstruction, sepsis and soiling. Bowel anastomosis with a skin stapler is safe, simple and efficient in time and materials.

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We report an unusual case of a pharyngeal diverticulum arising as a result of extrusion of a bone graft inserted during anterior cervical fusion operation. The dense scar tissue at the site of extrusion of the bone graft probably caused traction on the posterior pharyngeal wall, with the development of a pharyngeal pouch. This is believed to be the first case with acquired pharyngeal diverticulum following anterior cervical fusion to be recorded in the literature.

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Although a fixed appliance may ultimately be required to correct a malocclusion, the author gives examples of how the use of a removable appliance initially could simplify the treatment. A removable appliance enables the benefits of growth and development that are occurring in young patients to be enlisted in the treatment, and thereby reduces the overall treatment time.

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Velopharyngeal function, voice and speech changes following uvulopalatopharyngoplasty (UPPP) were studied prospectively and compared with those in an age and sex matched group undergoing tonsillectomy. The fundamental frequency of voice was significantly lower in those undergoing UPPP. All the other changes studied were not significantly different in the two groups.

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Parents of children undergoing (adeno) tonsillectomy were questioned about their preferences for a period of hospitalization. The proportion wanting early discharge increased as their children recovered after surgery.

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Steroids and control of post-tonsillectomy pain.

J Laryngol Otol

July 1993

Department of Otolaryngology, South Warwickshire Hospital, Warwick.

A prospective, randomized, double-blind study to assess the effect of steroids on post-tonsillectomy pain was performed on 82 adults. The premedication, anaesthesia, surgical technique and post-operative analgesia were standardized. Pain was assessed on a visual analog scale.

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Middle meatal antrostomy: long-term patency and results in chronic maxillary sinusitis. A prospective study.

Clin Otolaryngol Allied Sci

April 1993

Department of Otolaryngology and Head and Neck Surgery, South Warwickshire Hospital, Warwick, UK.

This prospective study included 51 patients with chronic maxillary sinusitis who had 90 middle meatal antrostomy procedures. The aim of the study was to examine the long-term patency of the antrostomy 18-30 months post-operatively (average 26 months) and the relationship between the degree of patency and the degree of improvement in each of the symptoms of chronic maxillary sinusitis. Our results showed patency as follows: 80% widely patent (more than 8 mm), 9% patent (5-8 mm), 4.

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This prospective randomized study investigates whether the use of antibiotic/steroid ear drops (Betnesol-N) is effective in reducing early post-operative otorrhoea and blockage of ventilation tubes (VTs). The study included 162 children who had bilateral VT insertion and used Betnesol-N ear drops in one ear only for three days after surgery, the other ear was left as control. These children were reviewed two weeks later and their ears were examined for VT patency, presence of blood or of mucopus.

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Post-tonsillectomy pain with diathermy and ligation techniques. A prospective randomized study in children and adults.

Clin Otolaryngol Allied Sci

December 1992

Department of Otolaryngology and Head and Neck Surgery, South Warwickshire Hospital, Warwick, UK.

150 patients (80 children and 70 adults) were entered into a prospective randomized study to compare the post-tonsillectomy pain of unipolar diathermy as opposed to ligation for haemostasis. In children, we found no difference in post-operative pain between the diathermy and ligation techniques. However, in adults there was a significant difference, more post-operative pain occurring with diathermy.

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A 51-year-old female presented with a sensation of a lump in the throat for five months. Clinical examination was normal. The barium swallow and the CT scan showed a well-defined mass to the left of the upper oesophagus and behind it.

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Fifty four of 74 paediatricians in the West Midlands (43 general medical, 11 subspecialist) replied to a postal questionnaire about their outpatient practice: 37 timed each consultation in one clinic. On average, subspecialty consultations lasted 37 minutes for new patients and 29 minutes for review. In general clinics new patient consultations took 23 minutes, review 12.

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