A paraneoplastic case of palmar fasciitis and polyarthritis syndrome.

Background: A 58-year-old woman presented with arthritis of the small joints of her hands and rapidly progressive joint contractures. She was wheelchair bound within 2 months of the onset of her symptoms. Physical examination revealed synovitis of the small joints of her hands and palmar fasciitis.

A dog's detection of low blood sugar: a case report.

One of the life threatening complications of diabetes is hypoglycaemia. It is a common complication, with times of greatest risk being before meals and during the night. Symptoms usually develop when the blood glucose level falls below 3.

Secondary hypothyroidism in hereditary hemochromatosis: recovery after iron depletion.

We report the case of a 56 year old male with hereditary haemochromatosis complicated by hepatic cirrhosis, insulin treated diabetes mellitus, hypogonadism and secondary hypothyroidism, the latter which was corrected by iron depletion. This is only the second such case to be reported.

The use of etoricoxib to treat an idiopathic stabbing headache: a case report.

According to the International Headache Society, idiopathic stabbing headache (ISH), an indomethacin-responsive headache syndrome, is a paroxysmal disorder of short duration manifested as head pain occurring as a single stab or a series of stabs involving the area supplied in the distribution of the first division of the trigeminal nerve. Stabs last for approximately a few seconds, occurring and recurring from once to multiple times per day in an irregular frequency, with no underlying attributable disorder.Previously indomethacin was the principle treatment option for ISH, despite therapeutic failure in up to 35% of cases, until reports showed gabapentin, melatonin and selective cyclo-oxygenase-2 (COX-2) inhibitors were also possibly effective.

Steroid allergy in patients with inflammatory bowel disease.

Background: Contact allergy to a steroid enema leading to worsening of inflammatory bowel disease (IBD) has recently been reported. This study was designed to look for evidence of steroid allergy in patients with IBD.

Objectives: To look for the presence of steroid allergy in general, and steroid enema allergy in particular, in a cohort of IBD patients prepared to attend for patch testing.

All that is hypogonadal in haemochromatosis is not due to iron deposition.

Background: Hereditary haemochromatosis (HH) is an autosomal recessive condition resulting in excessive gastrointestinal absorption of iron, which may be deposited in various organs. Apart from diabetes, hypogonadism is the most common endocrinopathy associated with HH and is usually secondary to excess iron deposition in the anterior pituitary gland.

Aims And Methods: We present three patients with HH and hypogonadism.

Sodium metabisulfite--a marker for cosmetic allergy?

A 45-year-old woman developed dermatitis of the face after she applied a cosmetic package comprising day and night creams. Patch tests were performed with the British Contact Dermatitis Society (BCDS) standard, bases + preservatives, and cosmetic series in addition to samples of both creams and the individual constituents. She had positive tests to both cosmetic creams, sodium sulfite from the manufacturer's samples (5% white soft paraffin (WSP)), and sodium metabisulfite (1% pet) in our bases + preservatives battery.

Endocrinopathy of HFE-related hemochromatosis.

Hereditary hemochromatosis is a condition affecting many organs, as reflected by the fact that it is managed variably by hematologists, gastroenterologists, rheumatologists and endocrinologists, depending on local preferences. A potential pitfall of this approach is that certain aspects of diagnosis and management may be overlooked, particularly if they fall beyond the normal scope of practice of the specialist physician concerned. The purpose of this article is to review the nature of the endocrine complications of hereditary hemochromatosis, which have changed dramatically since the condition was first described over 100 years ago.