2 results match your criteria: "South China University of Technology Guangzhou 510006 China djzhi@scut.edu.cn.[Affiliation]"
Chem Sci
July 2022
Guangzhou First People's Hospital, Institutes for Life Sciences, School of Medicine, South China University of Technology Guangzhou 510006 China
[This corrects the article DOI: 10.1039/D0SC01146K.].
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May 2020
Guangzhou First People's Hospital, Institutes for Life Sciences, School of Medicine, South China University of Technology Guangzhou 510006 China
Herein, a versatile strategy for the construction of biofunctional Janus particles (JPs) through the combination of Pickering emulsion and copper-free click chemistry is developed for the study of particle-mediated cell-cell interactions. A variety of biomolecules including bovine serum albumin (BSA), ferritin, transferrin (Tf), and anti-signal regulatory protein alpha antibodies (aSIRPα), , can be incorporated into the Janus platform in a spatially defined manner. JPs consisting of Tf and aSIRPα (Tf-SPA1-aSIRPα JPs) demonstrate a significantly improved binding affinity to either macrophages or tumor cells compared to their uniformly modified counterparts.
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