High-adhesion ovarian cancer cell resistance to ferroptosis: The activation of NRF2/FSP1 pathway by junctional adhesion molecule JAM3.

Ovarian cancer remains a significant challenge due to the lack of effective treatment and the resistance to conventional therapies. Ferroptosis, a form of regulated cell death characterized by iron-depend and lipid peroxidation, has emerged as a potential therapeutic target in cancer. Ovarian cancer has been reported to exert an "iron addiction" phenotype which makes it is susceptible to ferroptosis inducers.

Approaching the standard quantum limit of a Rydberg-atom microwave electrometer.

The development of a microwave electrometer with inherent uncertainty approaching its ultimate limit carries both fundamental and technological significance. However, because of the thermal motion of atoms, the state-of-art Rydberg electrometer falls considerably short of the standard quantum limit by about three orders of magnitude. Here, we use an optically thin medium with approximately 5.

Theta Rhythm-Based Attention Switch Training Effectively Modified Negative Attentional Bias.

Background: Attentional bias modification training (ABMT) is commonly employed to regulate negative attentional bias (NAB) and, in turn, to prevent or alleviate depressive symptoms. Recent advancements in attention switch theory have facilitated the development of a novel training paradigm that may enhance the efficacy of such interventions.

Methods: A total of fifty-seven college students were assigned to two groups: one exhibiting NAB and the other without.

A recyclable dynamic semiconducting polymer consisting of Pauli-paramagnetic diradicaloids promoted and stabilized by catechol-boron coordination.

Coordination between 5,5',6,6'-tetrahydroxyindigo (4OH-ID) and boron tribromide unexpectedly affords a novel dynamic covalent polymer, namely P(ID-O-B), consisting of alternating indigo and indigo diradicaloid units. The catechol-boron dynamic bond plays a vital role in promoting the diradicaloid formation and stabilizing the formed diradicaloid segments. The diradicaloid segment in the polymer has a triplet ground state and a thermally populated doublet state, which has been confirmed by the EPR study.

Systematic investigation and validation of peanut genetic transformation via the pollen tube injection method.

Genetic transformation is a pivotal approach in plant genetic engineering. Peanut (Arachis hypogaea L.) is an important oil and cash crop, but the stable genetic transformation of peanut is still difficult and inefficient.

Talarergosteroids A-C: Three Unusual Steroid-Polyketone Conjugates with Antifungal Activity from a Derived Fungus sp.

Three previously undescribed steroid-polyketone conjugates, talarergosteroids A-C (-), together with talarergosteroid D (), which was first identified from a natural source, were isolated from a derived fungus sp. SCNU-F0041. Compounds and bear a complicated 6/6/6/5/6/6 hexacyclic ring system characterized by an oxaspiro[5.

Nanoscale‑boron nitride positively alters rhizosphere microbial communities and subsequent cucumber (Cucumis sativa) growth: A metagenomic analysis.

Boron (B) deficiency affects over 132 crop species globally, making effective B supplement crucial for enhancing agricultural yield and health. This study explores an innovative application of nanoscale boron nitride (nano-BN) as a sustainable solution for addressing B deficiency in crops. Cucumber seedlings were treated with different contents of nano-BN under greenhouse conditions and both B and N ionic treatments were set as comparisons.

Ferrocene-decorated graphene nanosheets built by edge-to-face π-π interaction for room temperature ppb-level NO sensing.

The development of materials toward ppb-level nitric oxide (NO) sensing at room temperature remains in high demand for the monitoring of respiratory inflammatory diseases. In order to find an iron-containing molecule without steric hindrance to combine with graphene for room temperature NO gas sensing, here a supramolecular assembly of ferrocene (Fc) and reduced graphene oxide (rGO) was designed and prepared for NO sensing. The assembly of Fc/rGO was characterized using FT-IR, TEM, and XPS measurements.

Mitigating epidemic spread in complex networks based on deep reinforcement learning.

Complex networks are susceptible to contagious cascades, underscoring the urgency for effective epidemic mitigation strategies. While physical quarantine is a proven mitigation measure for mitigation, it can lead to substantial economic repercussions if not managed properly. This study presents an innovative approach to selecting quarantine targets within complex networks, aiming for an efficient and economic epidemic response.

Discovery of a Gut Bacterial Pathway for Ergothioneine Catabolism.

Ergothioneine is a diet-derived micronutrient for humans. However, enzymes involved in the catabolism of ergothioneine in human gut bacteria have not yet been identified. Herein, we characterize a sulfidogenic pathway for gut bacterial catabolism of this micronutrient, which involves an unprecedented reductive desulfurization reaction catalyzed by members of the xanthine oxidoreductase family (XOR), a class of molybdenum-containing flavoproteins.

Extended DEMATEL method with intuitionistic fuzzy information: A case of electric vehicles.

The Decision-Making Trial and Laboratory (DEMATEL) methodology excels in the analysis of interdependent factors within complex systems, with correlation data typically presented in crisp values. Nevertheless, the judgments made by decision-makers often possess a degree of fuzziness and uncertainty, rendering the sole reliance on precise values inadequate for representing real-world scenarios. To address this issue, our study extends the DEMATEL approach to more effectively and efficiently handle intuitionistic fuzzy information, which denotes the factor correlation information from decision-makers in the form of intuitionistic fuzzy terms.

Greater neural pattern similarity to the native language is associated with better novel word learning.

Introduction: Previous neuroimaging studies on bilingualism revealed that individuals tend to apply their native-language (L1) neural strategies to second language (L2) learning and processing. Nevertheless, it is still unclear how the utilization of the L1 neural strategies affects visual word learning in a new language.

Methods: To address this question, the present study scanned native Chinese speakers while performing implicit reading tasks before 9-day form-meaning learning in Experiment 1 and before 12-day comprehensive word learning in Experiment 2.

Intrinsic Localized Excitons in MoSe/CrSBr Heterostructure.

Despite extensive studies on magnetic proximity effects, the fundamental excitonic properties of the 2D semiconductor-magnet heterostructures remain elusive. Here, the presence of localized excitons in MoSe/CrSBr heterostructures is unveiled, represented by a new photoluminescence emission feature, X. Our findings reveal that X originates from excitons confined by intrinsic defects in the CrSBr layer.

Mystery of gamma wave stimulation in brain disorders.

Neuronal oscillations refer to rhythmic and periodic fluctuations of electrical activity in the central nervous system that arise from the cellular properties of diverse neuronal populations and their interactions. Specifically, gamma oscillations play a crucial role in governing the connectivity between distinct brain regions, which are essential in perception, motor control, memory, and emotions. In this context, we recapitulate various current stimulation methods to induce gamma entrainment.

Interferon-stimulated gene subtypes as key indicators of immune landscape and survival outcomes in ovarian cancer.

Purpose: Ovarian cancer (OV) remains the most lethal gynecological malignancy, underscoring the critical need for robust prognostic biomarkers to enhance patient outcomes. In this study, we classified OV patients by their interferon-stimulated gene (ISG) expression profiles and investigated the associations between these subtypes, the immune microenvironment, and survival outcomes.

Methods: We employed consensus clustering in the TCGA-OV cohort (n = 376) to classify patients into ISG-related subgroups.

Relationship between parental involvement and children's positive mental character during early years: the moderating role of parent-teacher relationship and teacher-parent relationship.

Introduction: To explore the association between parental involvement and children's positive mental character, and examine the moderating effect of the relationship between teachers and parents.

Methods: The present study conducted latent moderated structural equation model among 167 Chinese preschool teachers and 1019 preschool children and their parents. Parents reported children's positive mental character and perceived relationships with their children's teachers while teachers reported their perceived relationships with each child's parents.

Environmental DNA/RNA metabarcoding for noninvasive and comprehensive monitoring and assessment of marine fishes.

Marine fisheries resources are under increasing threat, necessitating the development of new effective monitoring and management strategies. Environmental DNA (eDNA) and RNA (eRNA) metabarcoding has emerged as a non-invasive and sensitive alternative method for monitoring fish biodiversity and fisheries resources and assessing the fisheries impact of anthropogenic activities. Here, we summarize crucial technical details about eDNA metabarcoding for marine fish monitoring and provide meta-analytical trends in primer selection and sample size, assessment standards, fish and fisheries databases, reference fish genomic databases, and other relevant metrics.

Recent Progress and Challenges of Li-Rich Mn-Based Cathode Materials for Solid-State Lithium-Ion Batteries.

Li-rich Mn-based (LRM) cathode materials, characterized by their high specific capacity (>250 mAh g¹) and cost-effectiveness, represent promising candidates for next-generation lithium-ion batteries. However, their commercial application is hindered by rapid capacity degradation and voltage fading, which can be attributed to transition metal migration, lattice oxygen release, and the toxicity of Mn ions to the anode solid electrolyte interphase (SEI). Recently, the application of LRM cathode in all-solid-state batteries (ASSBs) has garnered significant interest, as this approach eliminates the liquid electrolyte, thereby suppressing transition metal crosstalk and solid-liquid interfacial side reactions.

Semantic Scene Completion in Autonomous Driving: A Two-Stream Multi-Vehicle Collaboration Approach.

Vehicle-to-vehicle communication enables capturing sensor information from diverse perspectives, greatly aiding in semantic scene completion in autonomous driving. However, the misalignment of features between ego vehicle and cooperative vehicles leads to ambiguity problems, affecting accuracy and semantic information. In this paper, we propose a Two-Stream Multi-Vehicle collaboration approach (TSMV), which divides the features of collaborative vehicles into two streams and regresses interactively.

Effect of Energy Density on Mechanical Properties of NiTiCu Shape Memory Alloys Prepared by SLM.

In the Ni-Ti shape memory alloy system, Cu elements are used to replace Ni elements. A NiTiCu alloy with a molar ratio of 45:50:5 was prepared using laser selective melting technology. The density, composition, microstructure, and mechanical properties of the NiTiCu alloy were investigated.

Research Progress on Methods for Improving the Stability of Non-Destructive Testing of Agricultural Product Quality.

Non-destructive testing (NDT) technology is pivotal in the quality assessment of agricultural products. In contrast to traditional manual testing, which is fraught with subjectivity, inefficiency, and the potential for sample damage, NDT technology has gained widespread application due to its advantages of objectivity, speed, and accuracy, and it has injected significant momentum into the intelligent development of the food industry and agriculture. Over the years, technological advancements have led to the development of NDT systems predicated on machine vision, spectral analysis, and bionic sensors.

Characteristics and Biological Activities of a Novel Polysaccharide R1 Isolated from Hu.

Raspberry ( Hu) is a Chinese herb that is rich in nutrients and has anti-inflammatory, antibacterial, antioxidant, anti-allergic, hypoglycemic, and other effects. A water-soluble polysaccharide was extracted from raspberry by using hot water extraction then purified by DEAE-Sepharose Fast Flow column chromatography. The structural characteristics of the polysaccharide (R1) are as follows: the molar ratio of the monosaccharide composition is Ara:Gal:Xyl:Glc:Man = 31.