67 results match your criteria: "South Bay Medical Center[Affiliation]"

In recent decades, artificial intelligence (AI) has infiltrated a variety of domains, including media, education, and medicine. There exists no glossary, lexicon, or reference for the uninitiated medical professional to explore the new terminology. As AI-driven technologies and applications become more available for clinical use in healthcare settings, an understanding of basic components, models, and tasks related to AI is crucial for clinical and academic appraisal.

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The purpose of this review is to provide an overview of the integration of technological advancements in orthopedic shoulder surgery. Recent technological advancements in orthopedic shoulder surgery include predictive analytics, computer-navigated instrumentation for operative planning, extended reality, and robotics. Separately, these advancements provide distinct methodological attempts to improve surgical experiences and outcomes.

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Natural Language Processing Versus Diagnosis Code-Based Methods for Postherpetic Neuralgia Identification: Algorithm Development and Validation.

JMIR Med Inform

September 2024

Department of Research & Evaluation, Kaiser Permanente Southern California, 100 S Los Robles Ave, 2nd Floor, Pasadena, CA, 91101, United States, 1 626-986-8665, 1 626-564-7872.

Article Synopsis
  • A study developed and validated a natural language processing (NLP) algorithm to identify postherpetic neuralgia (PHN) from unstructured electronic health records (EHRs), aiming to improve accuracy compared to traditional diagnosis codes and prescription data.
  • The research involved reviewing EHRs from a large health care system and comparing the NLP's performance with code-based methods by analyzing sensitivity, specificity, and other statistical measures.
  • Results showed the NLP algorithm had high sensitivity (90.9%) and specificity (98.5%), with notable advantages in identifying PHN cases compared to code-based methods, which exhibited much lower sensitivity (52.7%-61.8%).
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Readability of online patient education materials for shoulder instability surgery in English and Spanish.

J Shoulder Elbow Surg

October 2024

Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, CA, USA; Department of Orthopaedic Surgery, Kaiser Permanente South Bay Medical Center, Harbor City, CA, USA.

Background: Online patient education materials (OPEMs) exist to inform patient medical decisions, yet the average adult in the United States reads at an eighth-grade level and 50% of Medicaid patients read at or below a fifth-grade level. To appropriately meet US health literacy needs, the American Medical Association and National Institutes of Health recommend that patient education materials not exceed a sixth-grade level. The purpose of this study was to assess and compare the readability of English and Spanish online patient education materials pertaining to shoulder instability surgery.

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Prevalence of Adolescents Meeting Criteria for Metabolic and Bariatric Surgery.

Pediatrics

March 2024

Department of Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, University of California, San Diego School of Medicine, San Diego, California.

Background And Objectives: The American Academy of Pediatrics endorses metabolic and bariatric surgery (MBS) as a safe and effective treatment of severe obesity in children with class 3 obesity or with class 2 obesity and qualifying comorbidities. The study objective was to determine eligibility and characteristics of adolescents who qualify for MBS based on American Academy of Pediatrics guidelines.

Methods: This retrospective cohort study analyzed electronic health record data of 603 051 adolescents aged 13 to 17 years between January 1, 2018, and December 31, 2021.

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Unlabelled: Ongoing innovation leads to a continuous influx of new technologies related to shoulder arthroplasty. These are made available to surgeons and marketed to both health-care providers and patients with the hope of improving outcomes. We sought to evaluate how preoperative planning technologies for shoulder arthroplasty affect outcomes.

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Latent Tuberculosis Infection Treatment Practices in Two Large Integrated Health Systems in California, 2009-2018.

Open Forum Infect Dis

May 2023

Division of Epidemiologic Research, Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.

Background: Treatment of latent tuberculosis infection (LTBI) is highly effective at preventing active tuberculosis (TB) disease. Understanding LTBI treatment practices in US health system settings is critical to identify opportunities to improve treatment prescription, initiation, and completion, and thus to prevent TB disease.

Methods: We assessed LTBI treatment practices among a cohort of adults after their first positive LTBI test (tuberculin skin test [TST] or interferon gamma release assay [IGRA]) between 2009 and 2018 at 2 large integrated health systems in California.

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Dementia and readmission risk in patients with heart failure participating in a transitional care program.

Arch Gerontol Geriatr

July 2023

Department of Research and Evaluation, Kaiser Permanente Southern California, United States; Department of Health Systems Science, Kaiser Permanente Bernard J Tyson School of Medicine, United States. Electronic address:

Background: Cognitive impairment is prevalent in patients hospitalized for heart failure (HF). We aimed to generate further evidence on the value of dementia screening in hospitalized HF patients by examining whether and when dementia would be an independent risk factor for 30-day readmission while modeling permutations of known risk factors such as patient demographics, disease burden, prior utilization, and index hospitalization characteristics.

Methods And Results: A retrospective cohort study was employed, consisting of 26,128 patients (2,075 or 7.

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Background: The purpose of this study is to compare the incidence of complications associated with tension band wiring (TBW) versus plate osteosynthesis (POS) in the treatment of olecranon fractures.

Methods: We performed a retrospective cohort study of operatively treated adult olecranon fractures from an integrated healthcare system by multiple surgeons from January 2008 to December 2011. Patients were divided into two cohorts: fractures fixed using the tension band technique and fractures fixed using plate osteosynthesis.

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Reflex human papilloma virus (HPV) testing with "atypical squamous cells, cannot exclude high-grade squamous lesion (ASC-H)" cytologic diagnosis is not recommended by American Society for Colposcopy and Cervical Pathology guidelines. Studies have shown human papillomavirus (HPV)-negative ASC-H patients of increased age are low risk for cervical intraepithelial neoplasia 2 or worse (CIN2+) lesions on colposcopic follow-up. We retrospectively assessed the efficacy of reflex HPV testing in postmenopausal women with ASC-H in the Los Angeles County hospitals and clinics in a 5-year period.

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Importance: The comparative effectiveness of the most common operations in the long-term management of dyslipidemia is not clear.

Objective: To compare 4-year outcomes associated with vertical sleeve gastrectomy (VSG) vs Roux-en-Y gastric bypass (RYGB) for remission and relapse of dyslipidemia.

Design, Setting, And Participants: This retrospective comparative effectiveness study was conducted from January 1, 2009, to December 31, 2016, with follow-up until December 31, 2018.

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Background: Shoulder injury related to vaccine administration (SIRVA) accounts for more than half of all claims received by the National Vaccine Injury Compensation Program. However, due to the difficulty of finding SIRVA cases in large health care databases, population-based studies are scarce.

Objective: The goal of the research was to develop a natural language processing (NLP) method to identify SIRVA cases from clinical notes.

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Importance: COVID-19 is associated with systemic vascular damage; however, the risk posed to the retinal vasculature remains incompletely understood.

Objective: To assess if there is a change in the incidence of retinal vascular occlusions after COVID-19 infection.

Design, Setting, And Participants: This cohort study at an integrated health care organization (Kaiser Permanente Southern California) included patients without a history of retinal vascular occlusion who were diagnosed with COVID-19 infection between January 20, 2020, and May 31, 2021.

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Comparative effectiveness of gastric bypass and sleeve gastrectomy on predicted 10-year risk of cardiovascular disease 5 years after surgery.

Surg Obes Relat Dis

June 2022

Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California. Electronic address:

Background: Comparative evidence is needed when deciding which bariatric operation to undergo for long-term cardiovascular risk reduction.

Objectives: The Effectiveness of Gastric Bypass vs. Gastric Sleeve for Cardiovascular Disease (ENGAGE CVD) study compared the effectiveness of vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) operations for reduction of the American College of Cardiology and the American Heart Association-predicted 10-year atherosclerotic cardiovascular disease (ASCVD) risk 5 years after surgery.

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Risk for Shoulder Conditions After Vaccination: A Population-Based Study Using Real-World Data.

Ann Intern Med

May 2022

Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California (C.Z., I.A.L., L.S.S., W.C., L.Q., D.S.R., S.S.K., C.M., S.J.J.).

Article Synopsis
  • - The study explores the risk of shoulder conditions following intramuscular vaccinations, particularly in the deltoid muscle, using data from Kaiser Permanente Southern California between April 2016 and December 2017.
  • - Out of over 3.7 million vaccinations, only 371 cases of shoulder conditions were identified, leading to an estimated incidence rate of 0.99 per 10,000 vaccinations, with higher risks noted in adults, especially women and older individuals.
  • - Factors associated with increased risk included advanced age, female sex, specific vaccines, and simultaneous administration of vaccines among the elderly, indicating that certain populations may be more vulnerable to these shoulder issues post-vaccination.
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Background: There is a theoretical concern, unconfirmed by population-based challenge data, that clinically significant, immunologically mediated hypersensitivity occurs among β-lactams sharing side chains.

Objective: To determine the population-based allergy incidence associated with the use of β-lactams sharing exact R1 side chains (ampicillin, cephalexin, and cefaclor [ACC]), with or without a current ACC allergy or a sulfonamide antibiotic allergy for comparison.

Methods: All courses of ACC and trimethoprim-sulfamethoxazole used by any Kaiser Permanente California members in 2017 and 2018, with follow-up through January 2019, were identified along with their preexisting antibiotic allergy status and all new antibiotic-specific allergies reported within 30 days of course initiation.

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Article Synopsis
  • This study explored the effects of intraoperative urinary catheters on postoperative urinary retention (POUR) in patients undergoing total joint arthroplasty (TJA), examining data from 9,580 cases across 11 medical centers.
  • The findings indicated that POUR occurred in a small percentage of patients, with a slightly higher incidence in males, and no significant difference was found in POUR rates between those who had urinary catheters and those who did not.
  • However, the study revealed that patients with urinary catheters had a higher incidence of urinary tract infections (UTIs) post-surgery, suggesting that while catheters don't affect POUR rates, they do increase UTI risk.
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Systemic Mastocytosis: Advances in Diagnosis and Current Management.

Cancer Treat Res

November 2021

Pathology and Laboratory Medicine, Southern California Permanente Medical Group, South Bay Medical Center, 25825 S Vermont Ave, Los Angeles, CA 90710, USA.

Mastocytosis is a rare hematologic disorder characterized by abnormal proliferation and accumulation of neoplastic mast cells in various body sites. Isolated skin involvement is termed cutaneous mastocytosis (CM) and the term systemic mastocytosis (SM) refers to multi-organ involvement, most commonly of the bone marrow, skin, liver, and spleen. A subset of patients with SM have an associated clonal hematologic neoplasm which is most commonly myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myelogenous leukemia and this entity is termed SM with associated hematological neoplasm (AHN).

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Minimum Threshold of Bariatric Surgical Weight Loss for Initial Diabetes Remission.

Diabetes Care

January 2022

2Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA.

Objective: There are few studies testing the amount of weight loss necessary to achieve initial remission of type 2 diabetes mellitus (T2DM) following bariatric surgery and no published studies with use of weight loss to predict initial T2DM remission in sleeve gastrectomy (SG) patients.

Research Design And Methods: With Cox proportional hazards models we examined the relationship between initial T2DM remission and percent total weight loss (%TWL) after bariatric surgery. Categories of %TWL were included in the model as time-varying covariates.

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Platinum resistance in gynecologic malignancies: Response, disease free and overall survival are predicted by biochemical signature: A metabolomic analysis.

Gynecol Oncol

October 2021

Nagourney Cancer Institute, 750 East 29th Street, 90806 Long Beach, CA, USA; Metabolomycs, Inc., 750 East 29th Street, 90806 Long Beach, CA, USA; Memorial Medical Center of Long Beach, Todd Cancer Institute, 2810 Long Beach Blvd, Long Beach 90806, CA, USA; Department of Obstetrics and Gynecology, University of California Irvine (UCI) School of Medicine, 101 The City Drive South, Orange 92868, CA, USA.

Objective: Platinum resistance, defined as the lack of response or relapse within six months of platinum-based chemotherapy, is an important determinant of survival in gynecologic cancer. We used quantitative Mass Spectrometry to identify metabolic signatures that predict platinum resistance in patients receiving chemotherapy for gynecologic cancers.

Methods: In this study 47 patients with adenocarcinoma of the ovary or uterus who were candidates for carboplatin plus paclitaxel submitted blood for quantitation of metabolites and surgical specimens for the isolation 3-dimensional organoids used to measure individual patient platinum resistance, ex vivo.

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Background: Patient-reported outcome measures (PROMs) are validated questionnaires that are completed by patients. Arthroplasty registries vary in PROM collection and use. Current information about registry collection and use of PROMs is important to help improve methods of PROM data analysis, reporting, comparison, and use toward improving clinical practice.

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Importance: Electronic health records (EHRs) often include default alerts that can influence physician selection of antibiotics, which in turn may be associated with a suboptimal choice of agents and increased antibiotic resistance.

Objective: To examine whether removal of a default alert in the EHR to avoid cephalosporin use in patients with penicillin allergies is associated with changes in cephalosporin dispensing or administration in these patients.

Design, Setting, And Participants: This retrospective cohort study of a natural experiment included data on patients who had received antibiotic treatment in the hospital or outpatient setting in 2 regions of a large, integrated health system in California from January 1, 2017, to December 31, 2018.

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