199,206 results match your criteria: "South Africa; South African Cochrane Centre[Affiliation]"

Background: S. haematobium is a recognized carcinogen and is associated with squamous cell carcinoma of the bladder. Its association with high-risk(HR) human papillomavirus (HPV) persistence, cervical pre-cancer and cervical cancer incidence has not been fully explored.

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Prevalence of food and housing insecurity among direct support professionals in New York.

Disabil Health J

December 2024

Department of Labor Studies and Employment Relations, School of Management and Labor Relations, Rutgers University, 94 Rockafeller Rd., Piscataway, NJ USA 08854, United States.

Background: Low earnings are associated with household insecurity. Direct Support Professionals (DSPs) provide support for people with intellectual and developmental disabilities, typically for wages close to state minimums, and may experience insecurity.

Objective: The purpose of the study was to evaluate the prevalence of food and housing insecurity among DSPs.

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High-volume disease (HVD) and low-volume disease (LVD) definitions in metastatic hormone-sensitive prostate cancer (mHSPC) patients are based on conventional imaging (CI) (CT/MRI with bone scan [BS]) according to CHAARTED criteria. HVD and LVD definitions are associated with overall survival and are used for treatment decisions. It remains unknown how these definitions transfer to prostate-specific membrane antigen (PSMA) PET imaging.

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This study aimed to establish consensus on injury risk factors in netball via a combined systematic review and Delphi method approach. A systematic search of databases (PubMed, Scopus, MEDLINE, SPORTDiscus and CINAHL) was conducted from inception until June 2023. Twenty-four risk factors were extracted from 17 studies and combined with a three-round Delphi approach to achieve consensus.

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Effect of in vitro exposure of first-line antiretrovirals on healthy human spermatozoa on kinematics and motility.

Int Urol Nephrol

January 2025

Department of Urology, Faculty of Health Sciences, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa.

Purpose: Contemporary antiretroviral (ARV) medications are used by millions of men for HIV treatment worldwide. Limited data exist on their direct effect on sperm motility. This pilot study hypothesizes that in vitro exposure to ARVs will reduce sperm kinematic and motility parameter values.

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Background: Intimate partner violence (IPV) and violence against children are global issues with severe consequences. Intersections shared by the 2 forms of violence have led to calls for joint programming efforts to prevent both IPV and violence against children. Parenting programs have been identified as a key entry point for addressing multiple forms of family violence.

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Taxonomic revision of the SK 15 mandible based on bone and tooth structural organization.

J Hum Evol

January 2025

Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, Beijing 100044, China; CAS Center for Excellence in Life and Paleoenvironment, Beijing 100044, China.

The hominin mandible SK 15 was discovered in April 1949 in Swartkrans Member 2, dated to ∼1.4 Ma. Albeit distorted on the right side, the left and right corpus of SK 15 are relatively low and thick, even compared to most Early to Middle Pleistocene Homo specimens.

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Over the last 20 years, we have dramatically improved hydrometeorological data including isotopes, but are we making the most of this data? Stable isotopes of oxygen and hydrogen in the water molecule (stable water isotopes - SWI) are well known tracers of the global hydrological cycle producing critical climate science. Despite this, stable water isotopes are not explicitly included in influential climate reports (e.g.

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High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

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Decoding Plant-Based Green Synthesis of Zinc Oxide Nanoparticles.

Chem Biodivers

January 2025

Physics Department, Centre National de la Recherche Scientifique (Unité Mixte de Recherche 6283), Institut des Molécules et Matériaux du Mans, Le Mans Université, Le Mans, France.

This study presents, for the first time, the comparison of behavior between two commonly found plant species, their extracts, and their major constituents (glucose and sucrose constituting over 70% of their dried extract) to synthesize zinc oxide (ZnO) nanoparticles (NPs) from zinc nitrate hexahydrate. The findings underscore the critical role of sugars as key constituents in facilitating this synthesis. This research demonstrates that the process can occur at relatively low temperatures (120°C).

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Factors associated with contracting border malaria: A systematic and meta-analysis.

PLoS One

January 2025

School of Nursing and Public Health, College of Health Sciences, Howard College Campus, University of KwaZulu-Natal, Durban, South Africa.

Vector resistance, human population movement, and cross-border malaria continue to pose a threat to the attainment of malaria elimination goals. Border malaria is prominent in border regions characterised by poor access to health services, remoteness, and vector abundance. Human socio-economic behaviour, vectoral behaviour, access and use of protective methods, age, sex, and occupation have been identified in non-border regions as key predictors for malaria.

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This study proposes and analyses a revised predator-prey model that accounts for a twofold Allee impact on the rate of prey population expansion. Employing the Caputo fractional-order derivative, we account for memory impact on the suggested model. We proceed to examine the significant mathematical aspects of the suggested model, including the uniqueness, non-negativity, boundedness, and existence of solutions to the noninteger order system.

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Intimate partner violence (IPV) is a global issue with several social and health consequences. Global estimates indicate that one-third of women have experienced lifetime IPV. In 2013, sub-Saharan Africa recorded the highest rates of IPV.

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Homozygous Familial Hypercholesterolemia Treatment: New Developments.

Curr Atheroscler Rep

January 2025

Carbohydrate and Lipid Metabolism Research Unit, Department of Medicine, University of the Witwatersrand, Johannesburg, South Africa.

Purpose Of Review: Homozygous familial hypercholesterolaemia (HoFH) is characterized by marked elevation of low-density lipoprotein cholesterol (LDLC) and premature atherosclerotic cardiovascular disease. This is a review of novel pharmacological therapies to lower LDLC in patients with HoFH.

Recent Findings: Novel therapies can be broadly divided by whether their efficacy is dependent or independent of residual low-density lipoprotein receptor (LDLR) function.

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Purpose: Posterior tibial slope (PTS) influences knee kinetics and kinematics. The purpose of this study was to investigate morphology and variation within a sample of the black and white male and female population.

Method: 480 randomly selected lateral knee radiographs were included.

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TiO-ZnO functionalized low-cost ceramic membranes from coal fly ash for the removal of tetracycline from water under visible light.

Discov Nano

January 2025

Materials Science Innovation and Modelling (MaSIM) Research Focus Area, Faculty of Natural and Agricultural Sciences, North-West University, Mafikeng Campus, Private Bag X2046, Mmabatho, 2735, South Africa.

Hybrid wastewater treatment systems offer viable solutions to enhance the removal of complicated contaminants from aqueous system. This innovation has opened new avenues for advanced wastewater treatment processes. Herein, a novel TiO-ZnO functionalized coal fly ash-based ceramic membrane was fabricated by utilizing a combined pressing and sintering method.

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Background: Microfragmented adipose tissue has been proposed for intra-articular treatment of knee osteoarthritis. There are little data comparing the outcomes of treatment between microfragmented adipose tissue and other biological treatments.

Purpose: To perform a systematic review and meta-analysis comparing microfragmented aspirated fat injections to other orthobiologics, hyaluronic acid, and corticosteroid injections for symptomatic knee osteoarthritis.

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The Incidence and Aetiology of Maxillofacial Trauma and Concomitant Traumatic Brain Injury in a Johannesburg Tertiary Hospital.

J Craniofac Surg

January 2025

Department of Oral and Maxillofacial Surgery, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.

Objective: To investigate the incidence and etiology of maxillofacial trauma (MFT) and its association with traumatic brain injury (TBI).

Background: Anecdotal evidence suggests that there is an association between MFT and TBI and that higher incidences of TBI are associated with frontal bone and mid-facial fractures. Despite the large volume of maxillofacial facial fractures treated in the authors' unit, no study has been undertaken to establish the relationship between TBI and maxillofacial fractures.

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Background: Accurate assessment of cognitive impairment in low-income settings may require consideration of complex psychosocial variables (PV). Failure to consider the association of PV with biological factors, such as HIV, could lead to false classification of cognitive impairment. We investigated the impact of PV on cognitive performance in people with HIV (PWH) and without in a low-income area of Cape Town, South Africa.

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Background: People with Alzheimer's Disease (AD) often have neuropsychiatric symptoms. The Neuropsychiatric Inventory (NPI) is a validated tool for assessing the severity of these symptoms, but its applicability in a South African context remains unexamined. This study evaluated NPI-Q, a brief version of the NPI, in relation to cognitive performance and markers of brain atrophy and emotional regulation among older South African adults.

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Background: Dementia criteria require not only memory impairment, but additional impairment in at least one other cognitive domain, like visuospatial functioning. Cognitive measures assessing visuospatial function often involve drawing shapes. While these measures have proven reliable and valid in developed countries, their use in Low and Middle-income Countries (LMICs) is challenging due to cultural differences and low literacy.

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Background: Globally, diarrhoeagenic Escherichia coli (DEC) has been implicated in the spread of waterborne diseases and abattoir wastewater has played a role in its dissemination into watersheds. This study isolated and characterised DEC from the abattoir wastewater-impacted Iyi-Etu River and other water sources at the Amansea livestock market settlement.

Methods: A total of 96 water samples comprising river water (upstream, downstream 1, downstream 2), borehole, well, sachet and abattoir wastewater samples were tested for DEC.

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Expert Consensus on an Exercise Prescription Framework for Older People Living With HIV in a South African Setting-A Delphi Study.

J Assoc Nurses AIDS Care

January 2025

Levin Chetty, PhD, MMSHSC, SPTSHB, B-SPS, is an Academic Researcher, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, South Africa.

Well-established, regular exercise interventions for older people living with HIV (OPLWH) are beneficial. However, the fundamental principles of exercise prescription for this population have not been sufficiently explored. An expert panel of health care professionals engaged in a modified Delphi technique to explore their perceptions of, and gain their consensus on, an exercise prescription framework for OPLWH in a resource-poor South African setting.

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Genetic variability in snake venom and its implications for antivenom development in sub-Saharan Africa.

Trans R Soc Trop Med Hyg

January 2025

Pharm-Biotechnology and Traditional Medicine Centre (PHARMBIOTRAC), Faculty of Medicine, Mbarara University of Science and Technology, Mbarara 40006, Uganda.

Snake venom, a complex mixture of proteins, has attracted human attention for centuries due to its associated mortality, morbidity and other therapeutic properties. In sub-Saharan Africa (SSA), where snakebites pose a significant health risk, understanding the genetic variability of snake venoms is crucial for developing effective antivenoms. The wide geographic distribution of venomous snake species in SSA countries demonstrates the need to develop specific and broad antivenoms.

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The incidence of snakebite in South Africa and the challenges associated with lack of reporting.

Trans R Soc Trop Med Hyg

January 2025

School of Animal, Plant and Environmental Sciences, University of the Witwatersrand, Johannesburg, Gauteng, South Africa.

Background: Snakebite is a public health challenge that has a substantial impact on humans and snakes. Annually, millions of people are affected by snakebite globally but there is a paucity of detailed data on snakebite incidences. The aim of this study was to assess the patterns of snakebite incidences in South Africa.

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