202,021 results match your criteria: "South Africa; Columbia University Vagelos College of Physicians and Surgeons[Affiliation]"
Omega (Westport)
March 2025
Erasmus Happiness Economics Research Organization, Erasmus University Rotterdam, Rotterdam, The Netherlands; Faculty of Economics, University of Johannesburg, Johannesburg, South Africa; Faculty of Management, Open University of the Netherlands, Heerlen, the Netherlands.
Can narcissism help foster resiliency against adversity? In this study, we used Turkish panel data, to examine whether narcissism can buffer the negative impact of personal loss on change in subjective well-being in the wake of the Türkiye-Syria earthquakes of 2023. Results show that the adaptation to personal loss was stronger for individuals high on narcissism. At the same time, we found no evidence that individuals high on Machiavellianism or psychopathy - other Dark Triad traits - were better able to adapt to personal loss.
View Article and Find Full Text PDFSupport Care Cancer
March 2025
Cancer Support Community Delaware, 4810 Lancaster Pike, Wilmington, DE, 19807, USA.
Purpose: The primary purpose was to assess the feasibility and acceptability of a group health coaching (GHC) program with cancer patients and survivors; secondarily, to determine the preliminary effects of GHC on several behavioral lifestyle factors.
Methods: GHC was provided to people diagnosed with cancer via videoconference by trained health coaches across six GHC sessions over a 3-month period. Qualitative and quantitative data were collected.
J Mol Model
March 2025
Faculty of Science, Engineering and Agriculture, University of Venda, University Road, Thohoyandou, 0950, South Africa.
Context: Malaria and cancer tend to become drug-resistant a few years after a drug is introduced into clinical use. This prompts the search for new molecular structures that are sufficiently different from the drugs for which resistance has developed. The present work considers eight selected acylphloroglucinols (ACPLs) with proven antimalarial and/or anticancer activities.
View Article and Find Full Text PDFBasic Res Cardiol
March 2025
Cardiovascular and Metabolic Disorders Programme, Duke-NUS Medical School, 8 College Road, Singapore, Singapore.
Although many cardioprotective interventions have been shown to limit infarct size (IS), in preclinical animal studies of acute myocardial ischemia/reperfusion injury (IRI), their clinical translation to patient benefit has been largely disappointing. A major factor is the lack of rigor and reproducibility in the preclinical studies. To address this, we have established the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) small animal multisite acute myocardial infarction (AMI) network, with centralized randomization and blinded core laboratory IS analysis, and have validated the network using ischemic preconditioning (IPC).
View Article and Find Full Text PDFJAMA Psychiatry
March 2025
Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Importance: Expectancy effects are significant confounding factors in psychiatric randomized clinical trials (RCTs), potentially affecting the interpretation of study results. This narrative review is the first, to our knowledge, to explore the relationship between expectancy effects, compromised blinding integrity, and the effects of active treatment/placebo in psychiatric RCTs. Additionally, we present statistical and experimental approaches that may help mitigate the confounding impact of expectancy effects.
View Article and Find Full Text PDFPhytopathology
March 2025
Mendel University in Brno, Phytophthora Research Centre, Department of Forest Protection and Wildlife Management, Faculty of Forestry and Wood Technology, Zemědělská 3, 613 00 Brno, Brno, Czech Republic, 613 00;
is a long-established, well known and globally important genus of plant pathogens. Phylogenetic evidence has shown that the biologically distinct, obligate biotrophic downy mildews evolved from at least twice. Since, cladistically, this renders 'paraphyletic', it has been proposed that evolutionary clades be split into multiple genera (Runge et al.
View Article and Find Full Text PDFCells
March 2025
SAMRC Precision Oncology Research Unit (PORU), DSI/NRF SARChI Chair in Precision Oncology and Cancer Prevention (POCP) Pan African Research Institute (PACRI), University of Pretoria, Hartfield, Pretoria 0028, South Africa.
The peremptory need to circumvent challenges associated with poorly differentiated epithelial endometrial cancers (PDEECs), also known as Type II endometrial cancers (ECs), has prompted therapeutic interrogation of the prototypically intractable and most prevalent gynecological malignancy. PDEECs account for most endometrial cancer-related mortalities due to their aggressive nature, late-stage detection, and poor response to standard therapies. PDEECs are characterized by heterogeneous histopathological features and distinct molecular profiles, and they pose significant clinical challenges due to their propensity for rapid progression.
View Article and Find Full Text PDFActa Crystallogr C Struct Chem
April 2025
Protein Structure Function Research Laboratory, School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg 2050, South Africa.
Three multicomponent systems, namely, 2,4-diamino-6-phenyl-1,3,5-triazine-nicotinic acid (DAPT-NA), CHN·CHNO, (I), 2,4-diamino-6-phenyl-1,3,5-triazin-1-ium hydrogen malonate (DAPT-MMA), CHN·CHO, (II), and 2,4-diamino-6-phenyl-1,3,5-triazin-1-ium hydrogen (+)-dibenzoyl-D-tartarate (DAPT-DBTA), CHN·CHO, (III), have been synthesized and characterized via single-crystal X-ray diffraction, and their supramolecular interactions have been analysed. The formation of cocrystal (I) and salts (II) and (III) was confirmed through the widening of the C-N-C bond angle of the triazine moiety of 2,4-diamino-6-phenyl-1,3,5-triazine and the difference in the C-O bond distances between the carboxyl and carboxylate groups of the respective carboxylic acids. Cocrystal (I) and salt (II) form robust homomeric and heteromeric R(8) ring motifs through primary acid-base interactions and complementary base pairing.
View Article and Find Full Text PDFEmerg Microbes Infect
March 2025
Hospices Civils de Lyon (HCL), Centre National des virus des infections respiratoires, Institut des Agents Infectieux, Laboratoire de Virologie, Lyon, France.
Background: The epidemiology of respiratory viruses and vaccine effectiveness (VE) in the community is not well described. This study assessed VE against a positive test of influenza (VEf) and SARS-CoV-2 (VECov).
Methods: Data from two large networks of community-based laboratories in France were collected during standard of care in the 2023-2024 epidemic season (n = 511,083 RT-PCR tests).
This article examines how exposure to violence in childhood is linked to impaired cognitive functioning and academic performance. Children who reside in low- and middle-income countries (LMICs) are more likely to be exposed to violence yet their representation in published studies is often limited. Here, we conducted a systematic review to examine the evidence regarding the association between childhood violence exposure and cognitive outcomes assessed up to age 11 in children from LMICs.
View Article and Find Full Text PDFEcol Appl
March 2025
Grupo de Ecología de Poblaciones de Insectos, Instituto de Investigaciones Forestales y Agropecuarias Bariloche, INTA - CONICET, Bariloche, Rio Negro, Argentina.
Globalization has led to a significant increase in the establishment of forest plantations with exotic species and to the accidental introduction of forest insects worldwide. Cumulatively, these factors contribute to the increased occurrence of novel associations between phytophagous insects and trees, leading to new interactions between species that have not historically co-occurred. Here, we reviewed the patterns of novel associations between herbivorous insects and pines and eucalypts at a global scale and identified factors that could favor the occurrence of novel associations and their impacts on forestry.
View Article and Find Full Text PDFEnviron Microbiol Rep
April 2025
School of Chemical and Metallurgical Engineering, University of the Witwatersrand, Johannesburg, South Africa.
This study investigated the suitability of readily available and naturally occurring sources of microorganisms (inoculum) to use for the cultivation of sulphate-reducing bacteria (SRB) for acid mine drainage (AMD) remediation. The selected inocula included AMD water (AMD), mud (MUD) and reed-bed mud (RM) from the AMD surrounds, mealworms (MW), cow dung (CD) and raw sewage sludge (RS). The suitability of the different inoculum sources was evaluated by comparing the SO reduction and sulfide (S) production rates at three different pHs.
View Article and Find Full Text PDFISME Commun
January 2025
Department of Biology and Microbiology, South Dakota State University, 1224 Medary Avenue, Brookings, SD 57007, United States.
Microbes in soil navigate interactions by recognizing kin, forming social groups, exhibiting antagonistic behavior, and engaging in competitive kin rivalry. Here, we investigated a novel phenomenon of self-growth suppression (sibling rivalry) observed in USDA 110. Swimming colonies of USDA 110 developed a distinct demarcation line and inter-colony zone when inoculated adjacent to each other.
View Article and Find Full Text PDFGlob Ment Health (Camb)
February 2025
Department of Psychiatry Dalhousie University, Halifax, NS, Canada.
Healthcare workers in Africa face considerable stress due to factors like long working hours, heavy workloads and limited resources, leading to psychological distress. Generally, countries in the global north have well-established policies and employee wellness programs for mental health compared to countries in the global south. This scoping review aimed to synthesize evidence from published and grey literature on workplace mental health promotion interventions targeting African healthcare workers using Social Ecological Model (SEM) and the Job Demands-Resources (JD-R) model as an underlying theoretical framework for analysis.
View Article and Find Full Text PDFFront Nutr
February 2025
Department of Nutrition, Food Science, and Packaging, San Jose State University, San Jose, CA, United States.
Front Chem
February 2025
South African Institute for Advanced Materials Chemistry, University of Western Cape, Cape Town, South Africa.
The conversion of carbon dioxide (CO), a major greenhouse gas, into light olefins is crucial for mitigating environmental impacts and utilizing non-petroleum-based feedstocks. Thermo-catalytic CO transformation into valuable chemicals offers a promising solution to this challenge. This study investigates the effect of potassium (K) and manganese (Mn) promoters on CO conversion and CH selectivity over CoFe-ZSM-5 zeolites.
View Article and Find Full Text PDFClin Public Health Guidel
February 2025
MAGIC Evidence Ecosystem Foundation, Lovisenberg gata, Oslo, Norway.
Clinical practice guidelines (CPGs) are shared through various dissemination strategies using a range of dissemination products and channels. However, users may have different needs for accessing and understanding them. Patients and carers from low- and middle-income countries might face challenges in accessing CPGs such as inadequate systems for printed book distribution and insufficient and substandard photocopies.
View Article and Find Full Text PDFJ Obstet Gynaecol Res
March 2025
Precision Medicine and Integrated Nano-Diagnostics (P-MIND) Research Group, Office of the Dean, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa.
Aim: Preeclampsia (PE) is a severe pregnancy-related disorder characterized by hypertension and multi-organ failure, primarily affecting the maternal vasculature and placenta. The aim of this review is to explain the molecular mechanisms behind PE by investigating the relationship between exosome release and complement activation, which could provide insight into potential therapeutic targets.
Methods: This review analyzes existing literature on the role of the complement system and exosomes in the pathophysiology of PE.
Parasit Vectors
March 2025
Plant Genetics Research Unit, United States Department of Agriculture (USDA)-Agricultural Research Service, Columbia, MO, USA.
Background: Heterorhabditis are important biological control agents in agriculture. Two Heterorhabditis populations, S8 and S10, were isolated from agricultural soils in the United States of America. Molecular analyses, based on mitochondrial and nuclear genes, showed that these populations are conspecific and represent a novel species of the "Bacteriophora" clade.
View Article and Find Full Text PDFAntimicrob Resist Infect Control
March 2025
Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
Background: Transmission-based precautions (TBP) and the proper use of personal protective equipment (PPE) are essential in preventing hospital-acquired infections (HAIs) and in controlling the emergence and spread of antimicrobial resistance (AMR). This study, therefore, aimed to determine healthcare providers' compliance with TBP and its determinants in healthcare settings to help curb the burden of HAIs and AMR.
Method: This study was a cross-sectional, hospital-based research conducted among healthcare providers at four health facilities in the Fako division of Cameroon, from January 1 to May 31, 2024.
BMC Nurs
March 2025
NuMIQ Research Focus Area, School of Nursing, Faculty of Health Sciences, North West University, Mahikeng Campus, Private Bag X2046 Mmabatho 2745, Mafikeng, South Africa.
Arch Virol
March 2025
Department of Genetics, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa.
The complete genome sequence of fig leaf mottle-associated virus 2 (FLMaV2), a positive-sense single-stranded RNA virus with a genome length of 16,925 nucleotides, was determined via RT-PCR and rapid amplification of cDNA ends (RACE). Its genome organization resembles those of little cherry virus 2 (LChV2) and yam asymptomatic virus 1 (YaV1), both of which are currently classified as members of the genus Ampelovirus but differ from typical ampeloviruses. Phylogenetic analysis based on amino acid sequences of the RNA-dependent RNA polymerase and coat protein of members of the family Closteroviridae showed that FLMaV2 clustered with LChV2 and YaV1.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
March 2025
Department of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Pretoria, South Africa.
Introduction: Keloids have proved challenging to manage with various therapies providing variable success rates and recurrences. Alternative therapies or a multimodal approach is often necessary to ensure complete eradication and prevent recurrence. The use of radioactive creams or patches embedded with Holmium-166, Phosphorus-32 for superficial skin lesions has been documented to be safe and effective.
View Article and Find Full Text PDFEye (Lond)
March 2025
Department of Health Management Centre, Zhongshan Hospital, Fudan University, Shanghai, China.
Background: Cataracts, the leading cause of blindness globally, significantly impair vision and quality of life, particularly among the elderly. Despite advancements in cataract surgery, challenges in accessibility and economic disparities hinder the reduction of cataract burden, especially in low-income regions. This study examines the global prevalence and years lived with disability (YLDs) due to cataracts from 1990 to 2021, providing insights to inform public health strategies.
View Article and Find Full Text PDFTrends Parasitol
March 2025
Escuela Nacional de Estudios Superiores Unidad Mérida (ENES-Mérida), Universidad Nacional Autónoma de México, Mérida, Yucatán, Mexico.