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Unifying the predictive value of pretransplant FDG PET in patients with lymphoma: a review and meta-analysis of published trials.
Eur J Nucl Med Mol Imaging
January 2010
Department of Computed Tomography and Interventional Radiology, Sotiria General Hospital for Chest Disease, Athens, Greece.
Purpose: The predictive value of (18)F-FDG PET in patients with relapsing/refractory lymphoma who are receiving high-dose chemotherapy and autologous stem cell transplantation(ASCT) remains a matter of debate. Seminal reports on pretransplant ASCT indicated an adverse prognosis in patients with positive FDG PET scans. The lack of a uniform outcome measure along with the mixed histologies in various studies have hampered efforts to quantify this prognostic value.
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