16 results match your criteria: "Sorbonne University of Paris[Affiliation]"
Clues for improvement of research in objective structured clinical examination.
Med Educ Online
December 2024
OSCE Research Group, Sorbonne Université, Paris, France.
While objective clinical structured examination (OSCE) is a worldwide recognized and effective method to assess clinical skills of undergraduate medical students, the latest Ottawa conference on the assessment of competences raised vigorous debates regarding the future and innovations of OSCE. This study aimed to provide a comprehensive view of the global research activity on OSCE over the past decades and to identify clues for its improvement. We performed a bibliometric and scientometric analysis of OSCE papers published until March 2024.
View Article and Find Full Text PDFAerosol therapy in adult critically ill patients: a consensus statement regarding aerosol administration strategies during various modes of respiratory support.
Ann Intensive Care
July 2023
CHRU Tours, Médecine Intensive Réanimation, CIC INSERM 1415, CRICS-TriggerSep F-CRIN Research Network, and INSERM, Centre d'étude des Pathologies Respiratoires, U1100, Université de Tours, Tours, France.
Article Synopsis
- The clinical practice of aerosol delivery for critically ill adult patients using respiratory support devices is complex and controversial, prompting the need for clearer guidelines.
- A modified Delphi method was used to gather expert opinions from a panel of 17 international researchers to establish consensus on aerosol delivery techniques and identify areas needing further study.
- The resulting document includes 20 statements that review the safety and efficacy of aerosol therapies, largely based on low-level evidence, and emphasizes the need for future randomized clinical trials.
Aerosolised antibiotics in critical care.
Intensive Care Med
July 2023
Research Department, Departement Médico-Universitaire DREAM (DMU DREAM), Sorbonne University of Paris, Paris, France.
Long-term persistence with evolocumab treatment and sustained reductions in LDL-cholesterol levels over 30 months: Final results from the European observational HEYMANS study.
Atherosclerosis
February 2023
Amgen Inc., Thousand Oaks, CA, USA.
Background And Aims: Variability in low-density lipoprotein-cholesterol (LDL-C) level control at a population level is associated with poor cardiovascular outcomes. Limited data exist on LDL-C level variability or long-term persistence with the monoclonal antibody evolocumab in routine clinical practice. Using data from the HEYMANS registry, this analysis aimed to assess evolocumab persistence and discontinuation over 30 months of evolocumab treatment and to evaluate at a population level the variability in LDL-C level reductions during the study period.
View Article and Find Full Text PDFAerosolized polymyxins for ventilator-associated pneumonia caused by extensive drug resistant Gram-negative bacteria: class, dose and manner should remain the trifecta.
Ann Intensive Care
October 2022
Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care, La Pitié-Salpêtrière Hospital, Assistance-Publique Hôpitaux de Paris, Sorbonne University of Paris, Paris, France.
Characteristics of oral health literacy in Senegal: A cross-sectional study among women in the Department of Pikine.
J Public Health Afr
July 2022
Health Education and Promotion Laboratory, UFR of Odontology, Paris 7 University, Paris, France.
Senegal having a significant prevalence of socially differentiated oral diseases, oral health literacy (OHL), an individual and social resource, should be considered alongside a remedial response. This work aimed to analyze women's OHL characteristics. A cross-sectional study on 315 women in Pikine County was carried out, using the Oral Health Literacy-Adult Questionnaire (OHL-AQ) for the OHL data collection and a questionnaire for the women's socioeconomic characteristics data.
View Article and Find Full Text PDFNebulized antibiotics for ventilator-associated pneumonia: methodological framework for future multicenter randomized controlled trials.
Curr Opin Infect Dis
April 2021
Multidisciplinary Intensive Care Unit, Department of Anaesthesiology and Critical Care, Sorbonne University of Paris, La Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.
Purpose Of Review: Although experimental evidence supports the use of nebulized antibiotics in ventilator-associated pneumonia (VAP), two recent multicenter randomized controlled trials (RCTs) have failed to demonstrate any benefit in VAP caused by Gram-negative bacteria (GNB). This review examines the methodological requirements concerning future RCTs.
Recent Findings: High doses of nebulized antibiotics are required to reach the infected lung parenchyma.
Impact of socioeconomic status in patients hospitalised for COVID-19 in the Greater Paris area.
Eur Respir J
December 2020
Dept of Pulmonology, Avicenne Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne University of Paris Nord, INSERM1272, Bobigny, France.
https://bit.ly/3kuStXS
View Article and Find Full Text PDFIntraoperative pulmonary hyperdistention estimated by transthoracic lung ultrasound: A pilot study.
Anaesth Crit Care Pain Med
December 2020
Divisão de Anestesiologia do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av Doutor Eneas de Carvalho Aguiar, 255, São Paulo 0540300, Brazil.
Article Synopsis
- Transthoracic lung ultrasound is being studied as a way to detect pulmonary hyperdistention, which can occur during mechanical ventilation and is usually not detected by standard assessments.
- Eighteen patients with normal lungs were monitored during lower abdominal surgery while various levels of positive-end expiratory pressure (PEEP) were applied, and ultrasound data were compared to electrical impedance tomography findings.
- Results showed that an increase in the number of horizontal A lines in lung ultrasound correlated with decreasing intercostal space thickness, with six A lines identified as the threshold indicating hyperdistention, demonstrating the ultrasound's potential for clinical use in monitoring lung conditions during surgery.
Minimally Invasive Donor Hepatectomy for Adult Living Donor Liver Transplantation: An International, Multi-institutional Evaluation of Safety, Efficacy and Early Outcomes.
Ann Surg
January 2022
Department of Surgery, Section of Transplant Surgery, University of Chicago, Chicago, IL.
Objective: Evaluating the perioperative outcomes of minimally invasive (MIV) donor hepatectomy for adult live donor liver transplants in a large multi-institutional series from both Eastern and Western centers.
Background: Laparoscopic liver resection has become standard practice for minor resections in selected patients in whom it provides reduced postoperative morbidity and faster rehabilitation. Laparoscopic approaches in living donor hepatectomy for transplantation, however, remain controversial because of safety concerns.
Functional respiratory imaging of the airways in the acute respiratory distress syndrome.
Anaesth Crit Care Pain Med
April 2020
Department of Critical Care Medicine, Antwerp University Hospital, University of Antwerp, Wilrijkstraat 10, 2650 Edegem, Belgium.
Background: Alveolar flooding and airway obstruction are present in the acute respiratory distress syndrome. The impact of positive end-expiratory pressure on regional airway aeration has not been described.
Aim: To assess bronchial and lung recruitment and distension during an incremental positive end-expiratory pressure trial in patients with acute respiratory distress syndrome.
Lung Ultrasound in Emergency and Critically Ill Patients: Number of Supervised Exams to Reach Basic Competence.
Anesthesiology
April 2020
From the Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine (C.A., H.B., R.D., A.M., J.-M.C., J.-J.R.) the Department of Parasitology-Mycology (F.G.), La Pitié-Salpêtrière Hospital, Public Assistance of Paris Hospitals (AP HP), Sorbonne University of Paris, Paris, France Intensive Care Unit, Federal University of Rio Grande do Sul, Ernesto Dornelles Hospital, Moinhos de Vento Hospital, Postgraduate Program for Pulmonology Science, Porto Alegre, Brazil (F.L.D.N.) the Department of Emergency Medicine, 2nd Affiliated Hospital, Zhejiang University School of Medicine, Institute of Emergency Medicine, Hangzhou, China (Y.G., M.Z.) the Medical Intensive Care Unit, Peking Union Medical College Hospital, Beijing, China (W.C., D.B.) the Department of Critical Care Medicine, Peking University People's Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China (J.L., Y.A.) the Multidisciplinary Intensive Care Unit, Hospital Albert Einstein, São Paulo, Brazil (C.S.V.B.) the Department of Perioperative Medicine, Centre Hospitalo-Universitaire Clermont-Ferrand, University Clermont Auvergne, National Institute for Health and Medical Research (INSERM), National Center for Scientific Research (CNRS), Clermont-Ferrand, France (S.P.) University of São Paulo, Surgical and Trauma Intensive Care Unit, Hospital Das Clinicas, São Paulo, Brazil (F.P.C., L.M.) the Multidisciplinary Intensive Care Unit, Hospital da Bahia, Salvador and Santa Helena Hospital, Salvador, Brazil (E.J.S.L., J.N.) La Republica University, Intensive Care Unit, Hospital de Clínicas Dr. Manuel Qintela, University School of Medicine, Montevideo, Uruguay (A.C.) the Multidisciplinary Intensive Care Unit, Hospital Copa D'Or, Rio de Janeiro, Brazil (J.S.).
Background: Lung ultrasound is increasingly used in critically ill patients as an alternative to bedside chest radiography, but the best training method remains uncertain. This study describes a training curriculum allowing trainees to acquire basic competence.
Methods: This multicenter, prospective, and educational study was conducted in 10 Intensive Care Units in Brazil, China, France and Uruguay.
Ultrasound-based clinical profiles for predicting the risk of intradialytic hypotension in critically ill patients on intermittent dialysis: a prospective observational study.
Crit Care
December 2019
Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, La Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, Sorbonne University of Paris, Paris, France.
Background: Intradialytic hypotension, a complication of intermittent hemodialysis, decreases the efficacy of dialysis and increases long-term mortality. This study was aimed to determine whether different predialysis ultrasound cardiopulmonary profiles could predict intradialytic hypotension.
Methods: This prospective observational single-center study was performed in 248 critically ill patients with acute kidney injury undergoing intermittent hemodialysis.
Nebulized Antibiotics: Epithelial Lining Fluid Concentrations Overestimate Lung Tissue Concentrations.
Anesthesiology
August 2019
From the Sorbonne University of Paris, Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine, La Pitié-Salpêtrière hospital, Assistance Publique Hôpitaux de Paris, Paris, France.
Occlusion Rate and Visual Complications With Flow-Diverter Stent Placed Across the Ophthalmic Artery's Origin for Carotid-Ophthalmic Aneurysms: A Meta-Analysis.
Neurosurgery
April 2020
Interventional Neuroradiology Unit, Department of Neuroradiology, Pitié-Salpêtrière Hospital, Paris, France.
Background: Flow-diverter stents (FDSs) have recently gained acceptance for the treatment of intracranial aneurysms, especially for carotid-ophthalmic aneurysms (COAs). However, complications have been reported after coverage of side branches, especially the ophthalmic artery (OA).
Objective: To evaluate, through a meta-analysis, the occlusion rate, and the ophthalmic complications after treatment of COA by FDS.
Trendelenburg Position and Morbid Obesity: A Respiratory Challenge for the Anesthesiologist.
Anesthesiology
July 2019
From the Sorbonne University of Paris, Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care Medicine (J.-J.R., A.M., J.-M.C.) Department of Multidisciplinary and Oncologic Radiology (O.L.), La Pitié-Salpêtrière Hospital, Assistance Publique Hôpitaux de Paris, France University Clermont Auvergne, Department of Perioperative Medicine, University and Hospital Center of Clermont-Ferrand, France (J.-M.C.).