1,022 results match your criteria: "Sophia University.[Affiliation]"

Response of to Flooding with Physical Flow.

Plants (Basel)

December 2024

Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Chiyoda, Tokyo 102-8554, Japan.

Flooding causes severe yield losses worldwide, making it urgent to enhance crop tolerance to this stress. Since natural flooding often involves physical flow, we hypothesized that the effects of submergence on plants could change when combined with physical flow. In this study, we analyzed the growth and transcriptome of exposed to submergence or flooding with physical flow.

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Event-based surveillance is crucial for the early detection and rapid response to potential public health risks. In recent years, social networking services (SNS) have been recognized for their potential role in this domain. Previous studies have demonstrated the capacity of SNS posts for the early detection of health crises and affected individuals, including those related to infectious diseases.

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Beige adipocytes arise from white adipocytes in response to cold or other stimuli, known as browning of white adipose. Beige adipocytes play a role similar to that of brown adipocytes, express high levels of uncoupling protein 1 (UCP1), and are responsible for energy consumption via heat production, thus aiding in fat loss. Although histidine (His) and soy isoflavone (Iso) co-ingestion reportedly reduces food intake, body weight, and fat accumulation in female rats, the underlying mechanism remains unclear.

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Crystallographic analysis of G-clamp-RNA complex assisted by large scale RNA-binding profile.

Chem Commun (Camb)

December 2024

Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Miyagi 980-8577, Japan.

We present the X-ray crystal structure of a complex between a G-clamp and an internal loop motif of pre-mir-125a, selected from high affinity RNAs identified in a large-scale RNA-binding profile. This X-ray crystal structure reveals that the G-clamp interacts with three distinct guanine bases, forming robust bonds through hydrogen bonding and stacking interactions.

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Performance assessment of public transport networks: An AHP-ANP approach.

Heliyon

November 2024

School of Electrical Engineering, Computing and Mathematical Sciences, Curtin University, Perth, WA 6845, Australia.

Multi-criteria decision-making (MCDM) methods have been extensively employed by researchers in the public transport (PT) sector. While many studies utilize a single MCDM method, employing multiple MCDM methods can achieve more robust results. Furthermore, integrated MCDM methods have the potential to address the weaknesses and limitations inherent in single MCDM method.

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DFT-SCRF Calculations of Nitrogen Isotopic Reduced Partition Function Ratios for Amino Acids in Aqueous Solution at pH 7.4.

J Phys Chem A

December 2024

Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, Chiyodaku, Tokyo 102-8554, Japan.

Using the self-consistent reaction field (SCRF) method, the nitrogen isotopic reduction partition function ratio (RPFR), a fundamental physical quantity for theoretical consideration of equilibrium isotope effects, was evaluated by density functional theory (DFT) for 20 proteinogenic and two related amino acids under physiological conditions at pH 7.4. At this pH value, all amino acids were of the zwitterion-type form with α-NH and α-COO groups, regardless of the net charge of -1 (monoanion), 0 (zwitterion), or +1 (monocation).

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Nonadiabatic molecular dynamics simulations were performed to explore the photoisomerization pathway from isoxazole (iso-OXA) to oxazole (OXA), considering four electronic states. The XMS-CASPT2 and SA4-CASSCF theories were employed to describe these electronic structures, which were caused by 12 electrons in 11 orbitals with the cc-pVDZ + sp diffuse basis set; the Gaussian s- and p-type diffuse functions were extracted from Dunning's aug-cc-pVDZ function. The potential energy and its gradient at each time step were computed on-the-fly at these levels in the time evolution of the classical trajectory.

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Catalytic applications of DNA duplexes containing Ag-mediated cytosine-cytosine base pairs (C-Ag-C) have not been well investigated. In this study, we demonstrate a novel approach for forming highly active DNA-capped Ag nanoparticle (DNA-AgNP) catalysts for the reduction of 4-nitrophenol (4-NP) using sodium borohydride (NaBH). This approach is based on the generation of DNA-AgNPs from DNA duplexes containing C-Ag-C (DNA duplex-Ag).

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Virological characteristics of the SARS-CoV-2 XEC variant.

Lancet Infect Dis

December 2024

Division of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan; Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Collaboration Unit for Infection, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan; International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; International Vaccine Design Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; MRC-University of Glasgow Centre for Virus Research, Glasgow, UK. Electronic address:

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Background: A growing body of literature focuses on the role of benevolent childhood experiences (BCEs) in predicting adulthood well-being, in addition to adverse childhood experiences (ACEs). However, cross-cultural differences are generally ignored in this endeavor. Hence, this study aimed to explore the role of BCEs in predicting life satisfaction, resilience, and hopelessness.

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A Simple Regeneration Process Using a CO-Switchable-Polarity Solvent for Cellulose Hydrogels.

ChemSusChem

November 2024

Department of Materials and Life Sciences, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo, 102-8554, Japan.

Cellulose is one of the main components of plant cell walls, abundant on earth, and can be acquired at a low cost. Furthermore, there has been increasing interest in its use in environmentally friendly, carbon-neutral, sustainable materials. It is expected that the applications of cellulose will expand with the development of a simple processing method.

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Metal halide perovskite materials (MHPs) are promising for several applications due to their exceptional properties. Understanding excitonic properties is essential for exploiting these materials. For this purpose, we focus on CsPbBr3 single crystals, which have higher crystal quality, are more stable, and have no Rashba effect at low temperatures compared to other 3D MHPs.

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An ionic liquid containing arsonium cation.

Chem Commun (Camb)

November 2024

Faculty of Molecular Chemistry and Engineering, Kyoto Institute of Technology, Goshokaido-cho, Matsugasaki, Sakyo-ku, Kyoto 606-0962, Japan.

Cations in ionic liquids (ILs) are typically derived from ammonium or phosphonium structures with long alkyl chains, and it is well established that the central atom significantly influences the properties of the resulting ILs. In this study, an arsonium-based IL, trihexylmethylarsonium bis(trifluoromethylsulfonyl)amide, was synthesized. The arsonium cation was found to contribute to lower viscosity and higher ionic conductivity, while maintaining sufficient stability compared to its phosphonium counterpart.

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Trajectories of affective and cognitive well-being at times of COVID-19 containment policies in Italy.

Anal Soc Issues Public Policy

August 2024

The Ohio State University, Department of Human Sciences, 172 Arps Hall | 1945 North High Street, Columbus, OH 43210-1172 (USA).

This paper draws on a subsample (N=851) of respondents to ITA.LI - Italian Lives - a recently established panel study on a probability sample of individuals aged 16+ living in Italy - to track changes in the affective (positive and negative emotions such as energy and sadness) and cognitive (life satisfaction) components of well-being during different COVID-19 policy phases, classified according to the severity of key government responses. An event-study design is employed, which uses mixed-effects ordered logistic models to investigate the change in SWB scores.

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Variational benchmarks for quantum many-body problems.

Science

October 2024

Institute of Physics, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

The continued development of computational approaches to many-body ground-state problems in physics and chemistry calls for a consistent way to assess its overall progress. In this work, we introduce a metric of variational accuracy, the V-score, obtained from the variational energy and its variance. We provide an extensive curated dataset of variational calculations of many-body quantum systems, identifying cases where state-of-the-art numerical approaches show limited accuracy and future algorithms or computational platforms, such as quantum computing, could provide improved accuracy.

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Article Synopsis
  • Since 2019, SARS-CoV-2 has mutated, leading to various pandemic and epidemic waves that involve changes in its spike protein, which is key for the virus's entry into cells.
  • Researchers studied the spike proteins from variants BA.2.86 and JN.1, discovering structures where ACE2 receptor binds to the spike protein in both up and down conformations.
  • Their findings suggest that the down-conformation of the receptor-binding domain (RBD) is an important intermediate state that helps facilitate the virus's entry, with specific mutations like K356T impacting infectivity and resistance to neutralizing antibodies.
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Pre-mRNA splicing is a fundamental process in eukaryotic gene expression, and the mechanism of intron definition, involving the recognition of the canonical GU (5'-splice site) and AG (3'-splice site) dinucleotides by splicing factors, has been postulated for most cases of splicing initiation in plants. Splice site mutations have played crucial roles in unraveling the mechanism of pre-mRNA splicing . Typically, splice site mutations abolish splicing events or activate one or more cryptic splice sites surrounding the mutated region.

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This article reports on recycling e-wastes using a VVF power cable as a model through a rapid pyrolytic process following exposure to microwave radiation. This occurred three possible pathways: (i) discharges at the copper wire on exposure to microwaves, with heat produced causing the thermal decomposition of the covering material - a relationship exists between the length of the copper wire and the wavelength of the microwaves; (ii) microwave heating softened the wire's covering material and ultimately led to its decomposition - in addition, the coating material carbonized by the discharge is rapidly heated by microwaves; (iii) the carbonaceous component present in the covering material absorbed the microwaves, causing the thermal decomposition. On the other hand, for VVF cables longer than 12 cm canceled the wavelength-dependent process, and the longer the VVF cable was, the more efficient was the microwave-induced pyrolysis, therefore eliminating the need to pre-cut the waste VVF cable into smaller pieces.

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Continuous process design of the microwave chemical recycling of waste plastics using microwave-absorbing heating elements.

Sci Rep

September 2024

Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo, 102-8554, Japan.

Conventional pyrolysis methods to chemically recycle plastic waste require significant energy input owing to inefficient energy transfer from the heat sources to plastics and the generation of excess CO. Accordingly, there is an urgent need to develop alternative methods for the chemical recycling of waste plastics to limit global warming. In this study, the use of microwaves (MWs) as an efficient energy source for pyrolysis and chemical recycling.

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People with higher systemizing traits have wider right hands.

Front Psychiatry

September 2024

Developmental Disorders Section, Department of Rehabilitation for Brain Functions, Research Institute of National Rehabilitation Center for Persons with Disabilities, Tokorozawa, Saitama, Japan.

Introduction: Various genetic mutations have been implicated in autism spectrum disorder (ASD). Some candidate genes for ASD are known to be related to signal transduction and may be involved in hand development as well as neurodevelopment. Therefore, although subtle, anatomical variations in hand configurations may be observed in individuals with ASD.

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Cyclodextrin-Based Nanogels for Stabilization and Sensing of Curcumin.

ACS Appl Nano Mater

September 2024

Micro and Nano-Systems (MNS), Department of Electrical Engineering (ESAT), Katholieke Universiteit Leuven (KU Leuven), 3001 Leuven, Belgium.

Curcumin (CUR), a polyphenolic substance from turmeric, displays diverse medicinal properties. However, its instability poses challenges in detection. Cyclodextrin-based nanogels (CyDngs) offer a transformative solution, enhancing CUR's stability in aqueous solutions.

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SUMO1 modification of 0N4R-tau is regulated by PIASx, SENP1, SENP2, and TRIM11.

Biochem Biophys Rep

September 2024

Department of Information and Communication Sciences, Faculty of Science and Technology, Sophia University, Tokyo, 102-8554, Japan.

Tau is a microtubule-associated protein that contributes to cytoskeletal stabilization. Aggregation of tau proteins is associated with neurodegenerative disorders such as Alzheimer's disease. Several types of posttranslational modifications that alter the physical properties of tau proteins have been identified.

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Transglutaminase mediates the hardening of fish egg envelope produced by duplication of factor XIIIA gene during the evolution of Teleostei.

J Biochem

December 2024

Department of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan.

Article Synopsis
  • The egg hardening process during fish fertilization is driven by an enzyme called transglutaminase (hTGase), which undergoes processing after fertilization.
  • Researchers isolated a specific version of this enzyme (Rt-hTGase) from rainbow trout eggs, finding that the unprocessed form is 80 kDa and the processed form is 55 kDa, both sharing similar amino acid sequences.
  • The study indicates that the C-terminal processing of Rt-hTGase does not enhance its activity, but it may enable better interaction with egg envelope proteins, facilitating the hardening process.
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Molecular and structural insights into SARS-CoV-2 evolution: from BA.2 to XBB subvariants.

mBio

October 2024

Division of Systems Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

Due to the incessant emergence of various SARS-CoV-2 variants with enhanced fitness in the human population, controlling the COVID-19 pandemic has been challenging. Understanding how the virus enhances its fitness during a pandemic could offer valuable insights for more effective control of viral epidemics. In this manuscript, we review the evolution of SARS-CoV-2 from early 2022 to the end of 2023-from Omicron BA.

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SF Negative Ion Formation in Charge Transfer Experiments.

Molecules

August 2024

Atomic and Molecular Collisions Laboratory, CEFITEC-Centre of Physics and Technological Research, Department of Physics, Universidade NOVA de Lisboa, 2829-516 Caparica, Portugal.

In the present work, we report an update and extension of the previous ion-pair formation study of Hubers, M.M.; Los, J.

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