1 results match your criteria: "Sophia Children's Hospital sk-0152[Affiliation]"
High serum levels of growth hormone (GH) and insulin-like growth factor-I (IGF-I) during high-dose GH treatment in short children born small for gestational age.
J Clin Endocrinol Metab
April 2006
Department of Pediatrics, Division of Endocrinology, Erasmus University Medical Center, Sophia Children's Hospital sk-0152, P.O. Box 2060, 3000 CB Rotterdam, The Netherlands.
Context: Epidemiological studies have indicated that high serum levels of GH and IGF-I are associated with long-term risks.
Objective: The objective of the study was to evaluate the changes in serum levels of GH during overnight profiles, IGF-I, and IGF binding protein 3 (IGFBP-3) in short small for gestational age (SGA) children during GH treatment with two doses.
Patients: Thirty-six prepubertal short SGA children were the subjects of this study.