[Surveillance of schistosomiasis 34 years after transmission interruption in Songjiang District, Shanghai City].

Objective: To analyze the surveillance data after schistosomiasis transmission interruption from 1985 to 2018, so as to provide scientific basis for the future prevention and control of schistosomiasis.

Methods: The data pertaining to snail survey, surveillance of schistosomiasis in humans and livestock, and health education were collected and analyzed in Songjiang District after schistosomiasis transmission interruption from 1985 to 2018.

Results: From 1985 to 2018, there were 8 townships, 68 villages and 1 462 settings with snails in Songjiang District, covering an area of 96.

Central But Not General Obesity Is Positively Associated with the Risk of Hyperhomocysteinemia in Middle-Aged Women.

Objective: Obesity and homocysteine (Hcy) are two important risk factors for cardiovascular disease (CVD). However, evidence on the association between obesity and Hcy concentration was conflicting. The aim of our study is to explore the associations of general and central obesity with hyperhomocysteinemia (HHcy) in middle-aged women.

Association between incidence of fatal intracerebral hemorrhagic stroke and fine particulate air pollution.

Objective: Few studies investigating associations between fine particulate air pollution and hemorrhagic stroke have considered subtypes. Additionally, less is known about the modification of such association by factors measured at the individual level. We aimed to investigate the risk of fatal intracerebral hemorrhage (ICH) incidence in case of PM (particles ≤ 2.

Lung cancer incidence in female rises significantly in urban sprawl of Shanghai after introduction of LDCT screening.

Objectives: LDCT screening for lung cancer has been widely used in China since the release of the NLST trial data in 2011, but little is known about its impact on the incidence and mortality rates of lung cancer in China.

Methods: Official cancer registry data of lung cancer incidence and mortality were collected by Shanghai Municipal Center for Disease Control and Prevention from 2005 to 2014. Two districts (Xuhui and Songjiang Districts) were selected to represent populations with different levels of accessibility to LDCT.

[A study on measles and rubella antibody level in 319 pairs of mothers and infants in Songjiang District of Shanghai].

To explore serum levels of measles and rubella IgG antibodies among mothers and infants. According to the inclusion and exclusion criteria, we selected 319 puerperae and their infants in maternal hospitals of Songjiang district November 2016 to February 2017, venous blood were collected and serum measles and rubella IgG antibodies were measured using ELISA. To study the correlation between the level of measles and rubella antibodies in infants and mothers' by using the Spearman's correlation analysis.

Detection of tuberculosis laboratory cross-contamination using whole-genome sequencing.

Objective: Detection of tuberculosis laboratory cross-contamination using whole-genome sequencing.

Methods: A total of 22 M. tuberculosis strains with high genotypic homology from one hospital were collected during the drug resistance surveillance.

[Epidemiological features of adult chronic kidney diseases in a community-based population in Songjiang district, Shanghai].

To investigate the prevalence and associated factors of chronic kidney diseases (CKD) in adult residents living in a community of Songjiang district, Shanghai. A total of 9 257 residents aged 20-75 years old in Xinqiao township of Songjiang district were selected by random cluster sampling. All the participants were interviewed to complete a set of personal questionnaire and undergo physical examinations.

Exposure of Adults to Antibiotics in a Shanghai Suburban Area and Health Risk Assessment: A Biomonitoring-Based Study.

An extensive exposure to antibiotics has been demonstrated in children and pregnant women by biomonitoring, but data from general adults remain limited. In the current study, we studied 822 adults aged 21-75 years in Shanghai in 2017 and analyzed 18 common antibiotics (five veterinary antibiotics (VAs), four human antibiotics (HAs), and nine human/veterinary antibiotics (H/VAs)) in spot urine by liquid chromatography coupled to high-resolution mass spectrometry. All 18 antibiotics were detected in urine with an overall detection frequency of 45.

Prenatal exposure to arsenic and neurobehavioral development of newborns in China.

The link between arsenic exposure and deficits in children's neurodevelopment has been suggested, but it remains unclear regarding the arsenic-related effects on the developing brain in early life. To investigate the associations of in utero arsenic exposure with neonatal neurobehavioral development, we conducted a cross-sectional study of 892 mother-infant pairs from 10 hospitals of different levels in Shanghai, China. The concentrations of arsenic were determined in cord blood samples.

Acceptance of Chemo-prophylaxis for Latent Tuberculosis Infection among High School/College Student Contacts of Tuberculosis Patients in Shanghai, China.

Student contacts of tuberculosis (TB) cases are susceptible to latent tuberculosis infection (LTBI), and chemo-prophylaxis can reduce the risk of active TB among them. This study aimed to assess the acceptance of chemo-prophylaxis for LTBI among students, and their concerns regarding TB and its preventive treatment. A total of 560 students contacts were included in the investigation.

Internal migration and transmission dynamics of tuberculosis in Shanghai, China: an epidemiological, spatial, genomic analysis.

Background: Massive internal migration from rural to urban areas poses new challenges for tuberculosis control in China. We aimed to combine genomic, spatial, and epidemiological data to describe the dynamics of tuberculosis in an urban setting with large numbers of migrants.

Methods: We did a population-based study of culture-positive Mycobacterium tuberculosis isolates in Songjiang, Shanghai.

Assessment of tuberculosis contact investigation in Shanghai, China: An 8-year cohort study.

Background: Tuberculosis (TB) contact investigation has been observed as a useful programmatic tool in active case finding. We collected data of contact cases to evaluate the effectiveness of TB contact investigation programme in Shanghai, China.

Methods: Since 2009, we screened and followed up the close contacts of bacteria-positive TB cases in Songjiang, Shanghai and calculated the incidence of TB in close contacts and confirmed the transmission by genotyping and sequencing.

[Risk analysis of imported schistosomiasis in Shanghai City from 2005 to 2015].

Objective: To understand the risk situation of imported schistosomiasis and its main influencing factors in Shanghai City from 2005 to 2015.

Methods: A retrospective survey was performed, and the database was established based on the data collection of imported schistosomiasis, snail situation and mobile population in Shanghai City from 2005 to 2015.

Results: From 2005 to 2015, the mobile population in Shanghai City increased by 123.

Hotspots of road traffic crashes in a redeveloping area of Shanghai.

To identify high-risk locations (hotspots) of road traffic crashes (RTC) in a redeveloping area of Shanghai, for formulating relevant countermeasures in similar areas. After geocoding the crash locations on electronic map, assessment of spatial clustering of accidents and hotspots spatial densities was conducted following Moran's I method, the kernel density estimation, the Ripley's K-function and the network-based kernel density estimation (NKDE). A total of 21,679 RTC incidents resulting in 24,147 victims were recorded from 2010 to 2012.

Tuberculosis-associated mortality in Shanghai, China: a longitudinal study.

Objective: To determine excess mortality in a cohort of people with tuberculosis in Shanghai.

Methods: Participants were local residents in 4 (of 19) districts in Shanghai, registered in one of four tuberculosis clinics between January 1, 2004 and December 31, 2008. Baseline data were collected at the most recent diagnosis of tuberculosis and mortality was assessed between March and May of 2014.

Melatonin Attenuates Oxidative Damage Induced by Acrylamide In Vitro and In Vivo.

Acrylamide (ACR) has been classified as a neurotoxic agent in animals and humans. Melatonin (MT) has been shown to be potentially effective in preventing oxidative stress related neurodegenerative disorders. In this study, whether MT exerted a protective effect against ACR-induced oxidative damage was investigated.

Transmission of Mycobacterium tuberculosis in China: a population-based molecular epidemiologic study.

Background: Understanding the transmission of Mycobacterium tuberculosis is essential for the development of efficient tuberculosis control strategies. China has the second-largest tuberculosis burden in the world. Recent transmission and infection with M.

[Immunological evaluation of the supplementary immunization activities of measles-containing vaccine in Songjiang district of Shanghai in 2010].

Objective: To evaluate the immunological effectiveness of the supplementary immunization activities of measles-containing vaccine (MCV) in Songjiang district of Shanghai in 2010.

Methods: 60 children with 1 dose, 2 doses, or ≥3 doses of MCV respectively were selected randomly, and the blood samples were collected from these children to test the measles IgG antibodies both before and one month after the supplementary immunization(SI), using enzyme-linked immunosorbent assay (ELISA).

Results: The positive rate of measles antibody before SI was not significantly different from that one month after SI (P=0.

[Meta analysis on the immunogenicity of domestic influenza virus vaccines].

Objective: To evaluate the immunogenicity of domestic influenza virus vaccines.

Methods: The published studies that compared the immunogenicity between domestic and imported influenza virus vaccines in Chinese population before September 2012 were collected and evaluated with meta analysis using Stata 10.0 software package.