Efficacy of Antibiotic Therapy Alone Versus Antibiotics With Percutaneous Drainage in Periappendiceal Abscess: A Systematic Review and Meta-Analysis.

Acute appendicitis is one of the most common surgical emergencies. Simple appendicitis can be a complicated periappendiceal abscess. Despite the fact that there are several treatment options for periappendiceal abscesses, there is no consensus on the optimal treatment method; some surgeons prefer appendectomy, while others prefer relying on non-operative approaches using antibiotic therapy with or without percutaneous drainage.

Postoperative Intravenous Fluids and Electrolytes Management After Gastrointestinal Surgery in a Sudanese Teaching Hospital: A Prospective Audit.

Background: Postoperative fluid and electrolyte management is crucial for adequate patients' recovery and healing. This audit aimed to assess the current practice of postoperative intravenous fluids (IV) and electrolyte administration and investigate postoperative electrolyte disturbances.

Method: This study was conducted at Soba Teaching Hospital and comprised two cycles, it examined adult patients who underwent abdominal surgery and were exclusively on postoperative intravenous fluid therapy for at least one day.

Intrafamilial and interfamilial heterogeneity of PINK1-associated Parkinson's disease in Sudan.

PINK1 is the second most predominant gene associated with autosomal recessive Parkinson's disease. Homozygous mutations in this gene are associated with an early onset of symptoms. Bradykinesia, tremors, and rigidity are common features, while dystonia, motor fluctuation, and non-motor symptoms occur in a lower percentage of cases and usually respond well to levodopa.

PLA2G6-associated late-onset parkinsonism in a Sudanese family.

Introduction: The phospholipase A2 group VI gene (PLA2G6) encodes an enzyme that catalyzes the hydrolytic release of fatty acids from phospholipids. Four neurological disorders with infantile, juvenile, or early adult-onset are associated with PLA2G6 genetic alterations, namely infantile neuroaxonal dystrophy (INAD), atypical neuroaxonal dystrophy (ANAD), dystonia-parkinsonism (DP), and autosomal recessive early-onset parkinsonism (AREP). Few studies in Africa reported PLA2G6-associated disorders and none with parkinsonism of late adult onset.

Methylation of alpha-synuclein in a Sudanese cohort.

Background: Several studies suggested a significant role of epigenetic changes, including alterations in miRNA, histone modifications, and DNA methylation of α-synuclein (SNCA) in Parkinson's disease (PD) pathogenicity. As of yet, only very few studies have been carried out in this field in Africa and none in Sudan.

Materials And Methods: We collected DNA from 172 Sudanese individuals (90 cases, 82 controls) who donated saliva for DNA extraction (mean age of onset: 40.

Mycetoma revisited. Incidence of various radiographic signs.

Objective: To define and quantitate various radiographic signs of mycetoma infection.

Methods: A retrospective study of 516 randomly selected patients seen between December 1996 and December 2004 at the Mycetoma Research Centre of Khartoum University, Khartoum, Sudan. All cases were confirmed by clinical examination, initial pretreatment radiographs, and histopathology.

Mycetoma of the hand.

Objective: To describe the incidence and radiographic signs of hand infection in mycetoma.

Methods: A retrospective review was carried out from the radiographic records of 516 confirmed cases of mycetoma seen between January 1994 and October 2002 at the referred outpatient clinic of the Mycetoma Research Center, Soba Teaching Hospital, Khartoum University, Khartoum, Sudan.

Results: The hands were involved in 24 (4.

New radiographic classification of bone involvement in pedal mycetoma.

Objective: The purpose of this study was to classify the pattern, extent, and severity of bone involvement in mycetoma of the foot.

Conclusion: In this classification, stage 0 indicates the presence of soft-tissue swelling without bone involvement. Stage I refers to the extrinsic pressure effects on the intact bones in the vicinity of an expanding granuloma.