7,834 results match your criteria: "Snakebite"

Background Snakebite envenomation remains a significant public health challenge in tropical countries, particularly affecting the pediatric population. Children are especially vulnerable because of their smaller body mass, outdoor activities, and delayed presentation to healthcare facilities. This study aimed to analyze the clinical profile, demographic patterns, and envenomation characteristics of snakebites in children aged 1-16 years presenting to a tertiary care center.

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Objectives: This study aimed to analyse the epidemiological patterns of paediatric snake bites in Sri Lanka over a 4-year period (2020-2024).

Methods: A multi-centre, retrospective observational study was conducted from June 2020 to June 2024 across nine governmental hospitals in seven provinces of Sri Lanka. Data were collected based on 757 children presenting with snake bites.

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Brain death due to intracranial hemorrhage in a child following suspected Bothrops snakebite.

Rev Soc Bras Med Trop

December 2024

Universidade Estadual de Londrina, Departamento de Ciências Farmacêuticas, Londrina, PR, Brasil.

Snakebites from the genus Bothrops are common and are responsible for the highest mortality rate in Brazil. Factors related to the species, treatment, and patient influence the clinical manifestations and prognosis of the condition. Young patients without comorbidities have better prognoses and rarely develop severe systemic complications.

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Article Synopsis
  • Snakebite envenoming poses a significant public health risk in tropical areas, particularly in Malawi, where community understanding of local snakes and first-aid measures is lacking.
  • A survey conducted in Neno District revealed that only 1.3% of participants could accurately identify snakes, less than 5% knew proper first-aid procedures, and 14.3% had adequate knowledge of prevention methods.
  • The findings indicate that both community health workers and members have inadequate knowledge, showing no significant differences between the two groups.
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Snakebite envenoming is a significant health threat, particularly in tropical regions, causing substantial morbidity and mortality. Traditional treatments, including antivenom therapy, have limitations and associated risks. This research aims to discover novel phytochemical antidotes for snakebites, specifically targeting the western diamondback rattlesnake () venom metalloproteinase Atrolysin.

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(Bl), a snake endemic to Martinique, is responsible for numerous envenomations annually, leading to severe complications such as thrombosis, necrosis, and hemorrhage. This case series investigates the link between envenomation and acute myocarditis, utilizing cardiac magnetic resonance imaging (MRI) to enhance management strategies. In both cases, cardiac MRI confirmed myocarditis with edema, and subsequent cerebral MRI revealed bilateral infarcts.

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Road Guarder (Conophis lineatus concolor: Dipsadidae): Case Documentation of a Clinically Significant Envenoming.

Toxicon

December 2024

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA; Division of Clinical Pharmacology and Toxicology, Department of Medicine, Hennepin County Medical Center (retired), Minneapolis, MN, USA. Electronic address:

Detailed cases of envenoming by a non-front-fanged snake (NFFS) from North, Central, and South America have had limited representation in the toxicology and toxinology literature. The NFFS, Conophis lineatus, has been reported to deliver bites that resulted in moderately severe envenoming. However, most of these reported cases have been via personal communication, or self-reported and lacking in detailed medical evaluations.

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We evaluated the efficacy of freeze-dried Bothrops-Lachesis-Crotalus antivenom and liquid Crotalus antivenoms to neutralize Crotalus durissus ruruima (Cdr) venom (Roraima, Brazil) comparing with C. d. terrificus (Cdt) venom.

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Background: Snakebite envenoming is a serious condition that affects 2.5 million people and causes 81,000-138,000 deaths every year, particularly in tropical and subtropical regions. The World Health Organization has set a goal to halve the deaths and disabilities related to snakebite envenoming by 2030.

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Background: Anaphylaxis is a systemic allergic reaction that is potentially life-threatening. Occupational anaphylaxis is an anaphylaxis that occurs in an occupational context. In this position paper, we propose diagnostic criteria for occupational anaphylaxis and provide an overview of the current state of knowledge in terms of prevalence, triggers, prevention, and management.

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Snakebites are a significant health issue, especially in tropical and subtropical regions. Envenomation from snakebites is a clinical emergency requiring prompt treatment. Recently, a new species of blunt-nosed viper, , was identified in central and southern Iran through morphological and molecular studies.

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Objective: Early antivenom administration is essential for effective treatment. We investigated the delays in antivenom administration.

Methods: We reviewed snakebites from the Australian Snakebite Project (2006-2021) given antivenom, presenting to hospital within 12 h.

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Broad-Spectrum Detoxification of Snake Venoms With Supramolecular Materials Integrated via Molecular Recognition and Coassembly.

Adv Healthc Mater

December 2024

College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin, 300071, P. R. China.

Article Synopsis
  • Snakebite is a serious medical issue in tropical and subtropical areas, requiring specific antivenoms to combat various snake venoms, which is both clinically and financially challenging.!* -
  • A new broad-spectrum antidote was developed using a combination of coassembled compounds to neutralize four toxic snake venom types, improving the effectiveness of treatment.!* -
  • The antidote demonstrated successful toxin neutralization in trials, enhancing survival rates of mice exposed to poisonous snake venom, highlighting the potential for broader applications in snakebite treatment.!*
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Introduction: Snakebite envenoming is a multidimensional issue that causes severe functional and life-challenging consequences among rural communities in tropical countries. Current research and treatments are largely focused on the acute effects of envenomation and short-term health outcomes. The knowledge of snakebite-induced long-term consequences is highly limited.

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Article Synopsis
  • The western pygmy rattlesnake is a small but dangerous snake native to several U.S. states, including Missouri and Tennessee.
  • Bites from this snake can lead to serious health issues like hospitalization and tissue damage.
  • A case study highlights a 56-year-old man who was bitten and required antivenom treatment and prolonged wound care.
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Introduction: Snakebite is a serious and potentially fatal public health concern, especially in tropical and subtropical regions, leading to severe complications. The World Health Organization (WHO) identified snakebite as a Neglected Tropical Disease (NTD) in 2017 and launched a global campaign in 2019 with the goal of halving the number of snakebite-related deaths and disability cases by half by the year 2030.

Case Presentation: A 26-year-old farmer male presented with a snake bite and soon developed neurological complications, including diplopia, seizures, and altered mental status with Glasgow coma scale(GCS) of 11 out of 15.

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Objective: To enhance the understanding of rhabdomyolysis (RM) caused by snakebites and to promptly identify and intervene in the risk factors associated with RM.

Methods: A retrospective analysis involving 209 snakebite victims who visited our hospital for snakebite cases was conducted. Among these, 43 were related to RM, while 166 did not exhibit RM (NRM).

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Venomous Peptides: Molecular Origin of the Toxicity of Snake Venom PLA-like Peptides.

JACS Au

November 2024

LAQV, REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, s/n, 4169-007 Porto, Portugal.

Snakebite envenoming claims 81-138 thousand lives annually, with vipers responsible for many of those. Phospholipase A (PLA) enzymes and PLA-like proteins are among the most important viper venom toxins. The latter are particularly intriguing, as three decades after their discovery, their molecular mechanism of toxicity is still poorly understood at best.

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Article Synopsis
  • A case involved a 35-year-old man who suffered a snakebite on his foot while sleeping and showed symptoms like headache and weakness before developing respiratory failure.
  • Quick medical intervention, including timely diagnosis and emergency intubation, is crucial for the survival of patients facing respiratory failure from snakebites.
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Article Synopsis
  • The observational study involved 52 patients, primarily male with a median age of 29, highlighting common envenomations, persistent symptoms, and treatments provided, including compression and physical therapy.
  • Key findings indicated that 61.5% of patients had persistent edema, with the clinic effectively addressing significant post-discharge issues through comprehensive wound care and referrals.
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Article Synopsis
  • Snakebite envenomation is a significant health issue in rural areas, with a study in Burkina Faso revealing that 42% of the 846 patients experienced complications after being bitten.
  • Complications were categorized into local issues such as wounds (23.2%) and systemic problems like hemorrhage and shock (34.3%), with 7.6% of those affected dying from their injuries.
  • Key factors that increased the risk of complications included living in rural areas, the application of tourniquets, the presence of abnormal vital signs, and a lack of antivenom treatment, emphasizing the need for better access to treatment and awareness.
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