153 results match your criteria: "Snake Envenomation Coral"
J Am Coll Emerg Physicians Open
October 2024
Am J Emerg Med
November 2024
Department of Pathology, Molecular, and Cell-based medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America. Electronic address:
Toxins (Basel)
May 2024
Department of Small Animal Clinical Sciences, Veterinary Teaching Hospital, University of Florida, 2015 S.W. 16th Ave, Gainesville, FL 32610-0144, USA.
This retrospective, observational study describes the clinical findings, case management trends, and outcomes of 83 dogs and nine cats exposed to eastern coral snakes in a university teaching hospital setting. The medical records of dogs and cats that received antivenom following coral snake exposure were reviewed. Data collected included signalment, time to antivenom administration, physical and laboratory characteristics at presentation, clinical course during hospitalization, length of hospitalization, and survival to discharge.
View Article and Find Full Text PDFNat Commun
May 2024
Department of Biotechnology and Biomedicine, Technical University of Denmark, DK-2800, Kongens, Lyngby, Denmark.
Oligoclonal mixtures of broadly-neutralizing antibodies can neutralize complex compositions of similar and dissimilar antigens, making them versatile tools for the treatment of e.g., infectious diseases and animal envenomations.
View Article and Find Full Text PDFToxins (Basel)
April 2024
Grupo de Toxinología y Alternativas Terapéuticas-Serpentario, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia (UdeA), Medellin 050010, Colombia.
Toxicon
March 2024
Instituto de Biotecnología, Universidad Nacional Autónoma de México, Avenida Universidad 2001, Chamilpa, C.P. 62210, Cuernavaca, Mor., Mexico.
Wilderness Environ Med
March 2024
Department of Emergency Medicine, Japan Self-Defense Force Central Hospital, Tokyo, Japan.
Emerg Med Pract
February 2024
Associate Professor, Department of Emergency Medicine, University of Florida College of Medicine-Jacksonville; Medical Director, Florida/USVI Poison Information Center-Jacksonville at UF Health, Jacksonville, FL.
There are approximately 10,000 emergency department visits in the United States for snakebites every year, and one-third of those involve venomous species. Venomous North American indigenous snakes include species from the Crotalinae (pit vipers) and Elapidae (coral snakes) subfamilies. Treatment relies on supportive care, plus antivenom for select cases.
View Article and Find Full Text PDFPLoS Negl Trop Dis
January 2024
Department of Biomedical Sciences, University of Padova, Padova, Italy.
Snake envenoming is a major, but neglected, tropical disease. Among venomous snakes, those inducing neurotoxicity such as kraits (Bungarus genus) cause a potentially lethal peripheral neuroparalysis with respiratory deficit in a large number of people each year. In order to prevent the development of a deadly respiratory paralysis, hospitalization with pulmonary ventilation and use of antivenoms are the primary therapies currently employed.
View Article and Find Full Text PDFAn Acad Bras Cienc
December 2023
Universidade Estadual de Campinas (UNICAMP), Departamento de Biologia Animal, Instituto de Biologia, Rua Monteiro Lobato, 255, Bloco P1, Cidade Universitária, 13083-862 Campinas, SP, Brazil.
Identifying risk areas for envenomation by animals is relevant for public health, such as strategic distribution of antivenoms. Coral snakes are highly diverse in the Amazon, inhabit natural and human-modified environments, and the outcome of the cases tends to be serious and potentially lethal due to their neurotoxic venom. By integrating species' geographical records and environmental variables, we used species distribution modeling to predict the distribution of coral snake species in the Brazilian Amazonia.
View Article and Find Full Text PDFToxicon
January 2024
AfriMed e.V., Mühlheim, Germany; Erongo Park, Omaruru, Namibia. Electronic address:
Shield-nose and Coral snakes (Aspidelaps spp.) are medium sized venomous snakes found throughout southern Africa. Little is known about the venom of these snakes and its clinical relevance, as human bites are uncommon.
View Article and Find Full Text PDFToxins (Basel)
October 2023
Grupo de Investigación en Animales Ponzoñosos y sus Venenos, Dirección de Producción, Instituto Nacional de Salud, Bogotá 111321, Colombia.
Braz J Biol
November 2023
Instituto Vital Brazil - IVB, Laboratório de Coleções Biológicas e Biodiversidade, Diretoria Científica, Niterói, RJ, Brasil.
Snakebite envenoming is a major global health problem that kills or disables half a million people in the world's poorest countries. Identifying the biting snake and its habitat use is key to understanding snakebite eco-epidemiology and optimizing its clinical management. To prevent and combat the neglected snakebite disease, we characterize the morphology, geographic distribution, habitat use, and snakebites of medically important venomous snakes in the state of Rio de Janeiro (Brazil).
View Article and Find Full Text PDFBiochimie
January 2024
Grupo de Investigación en Toxinología, Alternativas Terapéuticas y Alimentarias, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Medellín, Colombia; Centro de Investigación en Recursos Naturales y Sustentabilidad, Universidad Bernardo O'Higgins, Santiago, Chile. Electronic address:
In Colombia, the Micrurus genus comprises 30 species, including M. mipartitus and M. dumerilii, which are of major clinical relevance due to their wide geographical distribution and the number of snakebites inflicted by them.
View Article and Find Full Text PDFToxicon
September 2023
Vellore Institute of Technology, School of Biosciences and Technology, Vellore, Tamil Nadu, India. Electronic address:
Snakes play an important role as predators, prey, ecosystem regulators and in advancing the human economy and pharmaceutical industries by producing venom-based medications such as anti-serums and anti-venoms. On the other hand, snakebites are responsible for over 120,000 annual fatalities; due to snakebites people lose their lives and suffer from diseases such as snake envenoming, epilepsy, and symptoms such as punctures, swelling, haemorrhage, bruising, blistering, and inflammation. Moreover, there are several challenges associated with different interventions for managing snakebites.
View Article and Find Full Text PDFToxicon
March 2023
Programa de Pós-Graduação em Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, Brazil. Electronic address:
Micrurus surinamensis is a semi-aquatic coral snake found in primary forest region and can cause relevant human accidents. In this work we investigated the toxic and antigenic activities of the Peruvian Micrurus surinamensis venom (MsV). We found that MsV show hyaluronidase activity but lack LAAO and PLA enzymatic activities.
View Article and Find Full Text PDFToxicon
March 2023
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado - FMT-HVD, Diretoria de Ensino e Pesquisa, Av. Pedro Teixeira, w/n, Dom Pedro, 69040-000, Manaus, Amazonas, Brazil; Universidade do Estado do Amazonas - UEA, Escola Superior de Ciências da Saúde, Programa de Pós-Graduação em Medicina Tropical, Av. Carvalho Leal, 1777, Cachoeirinha, 69065-001, Manaus, Amazonas, Brazil. Electronic address:
Herein, we report three new separate cases of human envenomations by Micrurus hemprichii for the Amazon, which is a biome where envenomations by Micrurus are seldom reported. Two women were bitten after stepping on the snakes and one man was bitten while handling the animal. All cases occurred in the peridomicile, in rural areas.
View Article and Find Full Text PDFToxins (Basel)
December 2022
Instituto de Bioquímica Médica Leopoldo de Meis, Instituto Nacional de Biologia Estrutural e Bioimagem, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, Brazil.
For over a century, polyclonal antibodies have been used to treat snakebite envenoming and are still considered by the WHO as the only scientifically validated treatment for snakebites. Nevertheless, moderate innovations have been introduced to this immunotherapy. New strategies and approaches to understanding how antibodies recognize and neutralize snake toxins represent a challenge for next-generation antivenoms.
View Article and Find Full Text PDFInt J Mol Sci
November 2022
Biomolecules Discovery Group, Universidad Regional Amazónica Ikiam, Km 8 Via Muyuna, Tena 150101, Ecuador.
is a medically relevant genus of venomous snakes composed of 85 species. Bites caused by coral snakes are rare, but they are usually associated with very severe and life-threatening clinical manifestations. Ecuador is a highly biodiverse country with a complex natural environment, which is home to approximately 20% of identified species.
View Article and Find Full Text PDFToxins (Basel)
August 2022
Department of Biomedical Sciences, University of Padova, Via Ugo Bassi 58/B, 35131 Padova, Italy.
Snake envenoming is a major but neglected human disease in tropical and subtropical regions. Among venomous snakes in the Americas, coral snakes of the genus are particularly dangerous because they cause a peripheral neuroparalysis that can persist for many days or, in severe cases, progress to death. Ventilatory support and the use of snake species-specific antivenoms may prevent death from respiratory paralysis in most cases.
View Article and Find Full Text PDFToxicol Lett
October 2022
Laboratory of Pharmacology, Butantan Institute, São Paulo, SP, Brazil. Electronic address:
Coral snakes mainly cause neurotoxic symptoms in human envenomation, but experimental studies have already demonstrated several pharmacological activities in addition to these effects. This investigation was carried out with the aim of evaluating (1) non-neurogenic mechanisms involved in the inflammatory response induced by Micrurus lemniscatus venom (MLV) in rat hind paws, (2) participation of PLA in this response, and (3) neutralizing efficiency of commercial anti-elapid antivenom on edema. MLV promoted a rapid, significant increase in vascular permeability, influx of leukocytes, and disorganization of collagen bundles, as demonstrated by histological analysis.
View Article and Find Full Text PDFInt J Mol Sci
July 2022
Toxicology and Pharmacology, Campus Gasthuisberg O&N2, University of Leuven (KU Leuven), Herestraat 49, P.O. Box 922, B-3000 Leuven, Belgium.
Emerg Med Clin North Am
May 2022
Department of Medical Toxicology, Banner University Medical Center Phoenix, 1012 East Willetta Street, Fl 2, Phoenix, AZ 85006, USA; University of Arizona College of Medicine, Phoenix, AZ, USA.
This review discusses the distinct envenomation syndromes produced by North American species of snakes and arthropods, specifically the Crotalinae subfamily of snakes, which includes cottonmouths, copperheads, and rattlesnakes; coral snakes; Latrodectus and Loxosceles species of arachnid; and Centruroides sculpturatus, the only species of North American scorpion capable of producing an envenomation syndrome. The authors discuss the epidemiology, pathophysiology, and presentation of these syndromes and emphasize the varying degrees to which these syndromes can manifest clinically. Finally, the management of each envenomation syndrome is addressed.
View Article and Find Full Text PDFToxins (Basel)
April 2022
Grupo de Investigación en Toxinología, Alternativas Terapéuticas y Alimentarias, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia, Medellin 1226, Colombia.
In Colombia, the genus includes 30 species, of which and are the most widely distributed. causes less than 3% of the approximately 5000 cases of snakebite per year. The elapid envenomation caused by the snakes from the genus, are characterized by the severity of their clinical manifestations, due to the venom neurotoxic components such as three-finger toxins (3FTx) and phospholipases (PLA).
View Article and Find Full Text PDFBiomedica
December 2021
Grupo de Nutrición, Facultad de Salud, Universidad del Valle, Cali, Colombia.
We report two snakebites by Micrurus ortoni in Colombia and one by M. hemprichii in Perú. In two of the cases, we observed mild to moderate motor neurological involvement and in all patients, there was a marked sensory effect with hyperesthesia and hyperalgesia radiating from the bite site to the entire ipsilateral hemibody.
View Article and Find Full Text PDF