Off-label medicine use in pediatric inpatients: a prospective observational study at a tertiary care hospital in India.

Background. In the absence of standard pediatric prescribing information, clinicians often use medicines in an off-label way. Many studies have been published across the globe reporting different rates of off-label use.

Drug utilization in pediatric neurology outpatient department: A prospective study at a tertiary care teaching hospital.

Background: Neurological disorders are a significant cause of morbidity, mortality and adversely affect quality of life among pediatric patients. In India, more than 30% population is under 20 years of age, many of whom present late during the course of illness. Several drugs prescribed to pediatric population suffering from neurological disorders may be off label or unlicensed.

Assessment of the availability of technology for trauma care in India.

Background: We sought to assess the status of availability of technology for trauma care in a state in India and to identify factors contributing to both adequate levels of availability and to deficiencies. We also sought to identify potential solutions to deficiencies in terms of health system management and product development.

Methods: Thirty-two technology-related items were selected from the World Health Organization's Guidelines for Essential Trauma Care.

Successful retrieval of broken coiled guidewire from left atrium during balloon mitral valvotomy: a rare complication.

Abstract Balloon mitral valvotomy (BMV) is the procedure of choice for rheumatic mitral stenosis with favorable valve morphology. Fracture of 0.025 inch coiled guidewire during BMV is a very rare complication.

A study of mental health status of men who have sex with men in Ahmedabad city.

Background: Men who have sex with men (MSM), a unique group of people, feel, and believe they will face hardships in society once their identity is disclosed, but this does not deter them from dressing and behaving like the opposite sex in public life or fighting for their rights.

Objectives: To study the mental health status of MSM and their determinants.

Materials And Methods: Descriptive cross-sectional study was conducted among 410 MSM in the drop in centers of non-governmental organization working for MSM in Ahmedabad city through purposive sampling.

Percutaneous balloon pulmonary valvuloplasty: a modified over-the-wire Inoue balloon technique for difficult right ventricular anatomy.

Percutaneous balloon pulmonary valvuloplasty (BPV) is the mainstay of treatment for significant pulmonary stenosis with doming leaflets. Various techniques have been described in the literature including the use of Inoue Percutaneous Transseptal Mitral Commissurotomy (PTMC) catheter with standard 0.025″ guidewire.

Evaluation of antidiabetic prescriptions, cost and adherence to treatment guidelines: A prospective, cross-sectional study at a tertiary care teaching hospital.

Introduction: Diabetes mellitus is on alarming rise in India. Drug utilization studies help to identify the adherence to standard treatment guidelines and to evaluate the rational drug usage.

Objective: To study prescription pattern, calculate the cost of antidiabetic drugs and to evaluate the adherence to treatment guidelines in diabetic patients attending the medicine outpatient department in a tertiary care teaching hospital.

Drug utilization in emergency medicine department at a tertiary care teaching hospital: A prospective study.

Background And Objectives: The practice of emergency medicine has the primary mission of evaluating, managing and providing treatment to those patients with unexpected injury or illness. Instituting appropriate therapy is necessary for safety of the patients and to decrease mortality and morbidity. The objectives were to study the drug utilization pattern and direct cost of therapy in emergency medicine department of a tertiary care teaching hospital.

Evidence-based status of osteochondral cylinder transfer techniques: a systematic review of level I and II studies.

Purpose: Our purpose was to examine the Level I and II evidence for the use of osteochondral cylinder transfer technique (OCT) for cartilage repair.

Methods: A literature search was carried out for Level I and II evidence studies on cartilage repair using the PubMed database. All the studies that involved OCT were identified.

Utility of fine needle aspiration cytology in the evaluation of breast lesions.

Background: Fine Needle Aspiration Cytology (FNAC) is a simple, minimally invasive, cost effective, outpatient based and a rapid diagnostic method for breast lesions. The aim of the present study was to correlate cytological findings with histopathological findings and to determine the accuracy of FNAC in the diagnosis of breast lesions.

Material And Methods: A total of 222 breast aspirates were studied.

Randomized comparative trial of efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.

Objective: Paracetamol and ibuprofen are widely used for fever in children as monotherapy and as combined therapy. None of the treatments is proven clearly superior to others. Hence, the study was planned to compare the efficacy of paracetamol, ibuprofen and paracetamol-ibuprofen combination for treatment of febrile children.

Working through challenges of subclavian, innominate, and aortic arch regions during transradial approach.

Objectives: The aim of this review is to discuss different methods of working through subclavian, innominate, and aortic arch anatomical challenges to increase the success rate of transradial approach (TRA).

Background: Anatomical challenges in the subclavian, innominate, and aortic arch regions are important reasons for failure of TRA. There is limited modern literature describing methods to overcome these challenges and reduce TRA failure.

Situs Inversus Totalis (SIT) with Hepatocellular Carcinoma (HCC): A Rare Case Report and Review of 12 Other Cases.

Hepatocellular carcinoma (HCC) is the seventh-most common malignancy in males and ninth in females with incidence of one million new cases every year. Situs inversus totalis (SIT) is a rare congenital condition, in which there is a mirror-image transposition of both the abdominal and thoracic viscera. There are very few reported cases of HCC developing in people with SIT.

Splenic torsion in a child with polysplenia and situs inversus: a very rare presentation.

Polysplenia with situs inversus along with the torsion of spleen is a rare event. We report a case of a 12 year old child who presented with acute abdominal pain. There was an ill-defined mass in right hypochondrium and lumbar regions.

Internet addiction and its correlates among high school students: a preliminary study from Ahmedabad, India.

Purpose: Internet addiction (IA) is an upcoming and less researched entity in psychiatry, especially in low and middle income countries. This is the first such effort to study IA amongst Indian school students of class 11th and 12th and to find its correlation with socio-educational characteristics, internet use patterns and psychological variables, namely depression, anxiety and stress.

Methods: Six hundred and twenty one students of six English medium schools of Ahmedabad participated, of which 552 (88.

Objective structured practical examination as a tool for the formative assessment of practical skills of undergraduate students in pharmacology.

Introduction: Assessment for practical skills in medical education needs improvement from subjective methods to objective ones. An Objective Structured Practical Examination (OSPE) has been considered as one such method. This study is an attempt to evaluate the feasibility of using OSPE as a tool for the formative assessment of undergraduate medical education in pharmacology.

Working through complexities of radial and brachial vasculature during transradial approach.

Objectives: The aim of this review is to discuss different methods of working through radial artery (RA) and brachial artery (BA) vascular complexities to increase the success rate of transradial approach (TRA).

Background: Anatomical complexities of RA and BA vasculature are an important reason for failure of TRA. There are few current data describing methods to overcome these challenges and reduce TRA failure.

Percutaneous transvenous mitral commissurotomy: a modified over-the-wire technique for difficult left ventricle entry.

Percutaneous transvenous mitral commissurotomy (PTMC) is an acceptable and preferred alternative to surgical commissurotomy in suitable patients with severe rheumatic mitral stenosis. Various over-the-wire techniques have been described in the past for difficult left ventricle (LV) entry during PTMC. Here, we report two cases of successful PTMC with difficult LV entry with a new modified over-the-wire technique.

Life threatening deep scald burns in a neonate: A rare case report.

Domestic burns in neonate are rare in literature. Neonates are high risk for burns because of their thin and fragile skin, fluid overload or dehydration as the fluid balance range is small and immature immune system leading to septicaemia. Neonates are not small adults, owing to their different physiological response makes the management of neonates challenging as the clinical signs are different from the adults and the resuscitation protocols or end points are also different.