74 results match your criteria: "Smoker's Melanosis"

Clinical Profile and Prevalence of Oral Mucosal Lesions in Tobacco Users-A Prospective Study from Jammu, India.

Indian J Otolaryngol Head Neck Surg

June 2024

Government of Jammu and Kashmir Health and Family Welfare, Srinagar, Jammu and Kashmir India.

Article Synopsis
  • The study investigated the prevalence of tobacco-related oral mucosal lesions in adults visiting an ENT outpatient department at a hospital in India over the course of a year, including 400 patients categorized by current and former tobacco use.
  • Findings revealed that more males (55%) than females (45%) experienced oral mucosal lesions, with the most common issues being oral submucous fibrosis and leukoplakia.
  • Smokeless tobacco was predominantly used among patients (63.5%), and the labial commissure was the most affected area, indicating a significant need for regular oral examinations in tobacco users.
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Article Synopsis
  • The study investigates the link between smoking and oral lesions in the Iranian population, highlighting that the oral mucosa is the first to encounter harmful substances from tobacco.
  • Conducted with 200 participants (100 smokers and 100 non-smokers), the research examined various oral conditions and used statistical tests to analyze the data.
  • Results indicate that smoking significantly increases the risk of certain oral issues, like coated tongue and smoker's melanosis, while no strong association was found for leukoedema or other lesions.
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Background: Oral mucosa is encountered by various lesions and normal variants. Some are not to be worried about, whereas others may be of significance. Knowing the prevalence of oral mucosal lesions in a particular region helps better evaluate, diagnose, and, thus, manage these lesions.

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Article Synopsis
  • The study investigated the prevalence of oral lesions in 1000 individuals who use tobacco in various forms, including bidis, cigarettes, hookah, and gutkha.
  • Participants were assessed through demographic data collection and examination using the toluene blue staining method to identify associated oral lesions.
  • The research found several lesions linked to tobacco use, with the most common being tobacco pouch keratosis for chewers and leukoplakia for smokers.
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Oral and Systemic Manifestations in Leprosy a Hospital Based Study with Literature Review.

Indian J Dermatol

January 2022

Department of Oral Diagnosis, Medicine and Radiology, Faculty of Dental Sciences SGT University, Gurgaon, Haryana, India.

Article Synopsis
  • Leprosy is a chronic disease that affects peripheral nerves and muscles, with oral lesions observed in 20-60% of patients, particularly those with lepromatous leprosy, which can be infectious.
  • The study aimed to evaluate the occurrence of oral lesions in leprosy patients, analyzing factors such as age and gender while comparing primary lesions over time.
  • Out of 100 leprosy patients examined, 70% showed oral manifestations, including conditions like periodontitis and oral melanosis, with findings indicating a decrease in oral lesions due to advancements in treatment methods.
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Comparison of Er,Cr:YSGG laser and diode laser in the treatment of gingival melanin pigmentation: a randomized clinical trial.

Lasers Med Sci

February 2023

Periodontology Department, Faculty of Dentistry, Istanbul Okan University, Aydıntepe N. Prof. Dr. Necmettin Erbakan S. No:2 34947, Tuzla, Istanbul, Turkey.

Article Synopsis
  • * Both laser types showed similar overall effectiveness in depigmentation (p > 0.05), but the diode laser resulted in more repigmentation at the 1-year follow-up (p = 0.045).
  • * Patients in the Er,Cr:YSGG group experienced less pain and discomfort during the procedure (p = 0.007), indicating better pain management, though overall aesthetic satisfaction was similar for both groups.
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Article Synopsis
  • The study focuses on the oral health of individuals with type 1 and type 2 diabetes, highlighting that diabetes can lead to specific oral problems such as xerostomia (dry mouth) and chronic periodontitis.
  • Conducted at a diabetes care center in Chennai, the research involved comparing 110 diabetic patients with 100 healthy non-diabetic individuals to assess oral health using specific dental indices.
  • Results showed a significant link between diabetes and both xerostomia and periodontal disease, but did not support previous findings regarding other oral issues like traumatic ulcers and lichen planus.
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Background: Smoking and chewing tobacco carry significant risks for the development of oral cancer and premalignant lesions. The present study was conducted to find the prevalence of tobacco-related habits in Hazaribagh population and its association with oral mucosal lesion.

Methodology: The present study was carried out on patients who visited the Department of Oral Medicine And Radiology, Hazaribagh College of Dental Sciences And Hospital.

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Article Synopsis
  • The study aimed to evaluate precancerous and cancerous lesions in patients with tobacco habits and correlate clinical observations with histopathological findings.
  • A total of 1,500 tobacco users were examined, leading to a study group of 270 patients who presented various tobacco consumption patterns; 170 opted for biopsy, while 100 received counseling.
  • Results showed a high prevalence of oral lesions like leukoplakia and oral squamous cell carcinoma among patients, emphasizing the need for increased oral health education regarding the dangers of tobacco use.
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Article Synopsis
  • * A case study of a 34-year-old man with a germline STK11 mutation, lacking typical PJS features, reveals he developed lung adenocarcinoma despite being a non-smoker, highlighting the complexity of cancer genetics.
  • * Despite treatment efforts, the patient did not benefit from standard therapies and passed away 18 months after diagnosis, underscoring the need for vigilant monitoring of hereditary cancer syndromes like PJS for earlier cancer detection.
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Article Synopsis
  • A variety of black-pigmented lesions can occur in the oral cavity, ranging from benign conditions like melanotic macule and smoker's melanosis to the rare and aggressive oral malignant melanoma.
  • Oral melanoma accounts for only 0.5% of all oral cancers, primarily affecting areas like the palate and upper alveolar ridge, with poor prognosis and a 5-year survival rate of about 20%.
  • This report discusses a case of an unusual large oral melanoma found on the right buccal mucosa and right lower alveolar ridge, along with insights on diagnostic and prognostic immunohistochemical markers.
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Article Synopsis
  • - The study explored how tobacco smoking affects the prevalence of melanocytic nevi (moles) and lentigines (age spots) among a group of smokers and matched nonsmokers.
  • - A total of 59 smokers and 60 nonsmokers were examined, but the results showed no significant differences in the number of nevi or lentigines between the two groups, regardless of sun exposure.
  • - The conclusion indicates that tobacco use does not appear to influence the prevalence of these skin conditions, suggesting that smoking may not be a risk factor in this context.
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Oral pigmented lesions: a retrospective analysis from Brazil.

Med Oral Patol Oral Cir Bucal

May 2021

Department of Oral Diagnosis and Pathology Federal University of Rio de Janeiro School of Dentistry Av. Carlos Chagas Filho 373, Prédio do CCS, Bloco K, 2° andar, Sala 56 Ilha da Cidade Universitária, Rio de Janeiro/RJ. 21.941-902

Article Synopsis
  • - A study was conducted to analyze the occurrence and types of pigmented lesions in the oral mucosa within a Brazilian population over a 45-year period, finding that only 0.99% of diagnosed lesions were pigmented.
  • - The study revealed that out of 761 pigmented lesions, 46.1% were melanocytic and 53.9% non-melanocytic, with a higher prevalence in females aged 40-70, and the most common lesions identified were amalgam tattoos and melanotic macules.
  • - The results are consistent with previous research, underscoring the importance of understanding oral pigmented lesions to improve diagnostic capabilities and patient management in clinical practice.
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Global Prevalence of Tobacco Use in Adolescents and Its Adverse Oral Health Consequences.

Open Access Maced J Med Sci

November 2019

Department of Preventive Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Article Synopsis
  • * High-income countries showed the highest tobacco use among adolescents, with 24.76% of males and 19.4% of females smoking, while low-income countries had the lowest prevalence at 14.95%.
  • * Smoking is linked to various oral health issues, with conditions like gingivitis (72.8%) and dental caries being common among adolescent smokers, emphasizing the need for awareness and prevention efforts.
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Article Synopsis
  • Gingival melanin hyperpigmentation results from excess melanin in the gums, and the study investigates how long depigmentation lasts after using three types of lasers on smokers and nonsmokers.
  • Seventy-two participants were treated with Er:YAG, CO, and diode lasers, and results were evaluated using the Hedin Melanin Index at various intervals for up to 60 months.
  • The findings indicated that diode laser treatments had the longest stability, while smoking negatively impacted the duration of depigmentation, with Er laser leading to the quickest recurrence of pigmentation.
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Retrospective study on melanosis coli as risk factor of colorectal neoplasm: a 3-year colonoscopic finding in Zhuhai Hospital, China.

Int J Colorectal Dis

February 2020

Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing, China.

Article Synopsis
  • Melanosis coli (MC) is a condition characterized by dark pigmentation of the colon's mucosa, typically arising from long-term use of anthranoid laxatives.
  • A study at Zhuhai Hospital analyzed 12,776 patients and found a significant correlation between MC and an increased rate of colorectal (CR) neoplasms, showing that patients with MC were more likely to have hyperplastic polyps and low-grade adenomas.
  • The results indicate that lifestyle factors like drinking and smoking, along with older age, heighten the risk for neoplasms in patients with MC, suggesting a potential need to discontinue the use of anthranoid laxatives.
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Article Synopsis
  • Leprosy, a chronic disease affecting nerves and muscles, has been linked to oral lesions in 20-60% of patients, particularly in lepromatous leprosy, necessitating accurate diagnosis to prevent disease spread.
  • In a study of 100 leprosy patients, 70% exhibited oral manifestations, with conditions such as chronic periodontitis and oral melanosis being the most common.
  • This study is notably the first of its kind worldwide to document oral lesions in a significant number of leprosy cases, suggesting improved treatment outcomes have led to a decrease in the incidence of these lesions compared to older records.
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Article Synopsis
  • Black and brown pigmentation in the oral mucosa can arise from various non-cancerous factors, which may include both internal (endogenous) and external (exogenous) pigments.
  • Examples of conditions causing pigmentation include smoker's melanosis, drug-related changes, and systemic diseases, while external causes like amalgam tattoos and black hairy tongue are also noted.
  • Clinicians face challenges in diagnosing these pigmented lesions, and a biopsy is recommended when the cause cannot be clearly determined from a visual examination.
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Article Synopsis
  • - The study aimed to investigate the connection between oral mucosal lesions (OMLs) and tobacco and alcohol use in Guntur city, Andhra Pradesh, involving 300 participants selected through random sampling from different city zones.
  • - Findings revealed that 42.4% of participants had oral soft-tissue lesions, with nicotinic stomatitis being the most common among men and oral submucous fibrosis prevalent in women; leukoplakia was identified as the primary premalignant lesion.
  • - The research highlights significant links between smoking and chewing habits with OMLs, providing crucial data on specific lesions occurring in different demographics, such as illiterates showing a notable prevalence of leukoplakia.
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Pigmented lesions of the oral mucosa: A cross-sectional study of 458 histopathological specimens.

Oral Dis

November 2018

Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Article Synopsis
  • This study aimed to assess the clinical and histopathological characteristics of pigmented oral mucosal lesions over a 64-year period.
  • The research involved reviewing 34,127 archived specimens, finding that only 458 (1.34%) were pigmented lesions, primarily affecting middle-aged women.
  • The most common types of lesions identified were amalgam tattoos, melanotic macules, and nevi, predominantly located on the cheek mucosa and often appearing as small, flat spots.
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Article Synopsis
  • - Periodontal health is characterized by no detectable inflammation, and can exist in both healthy and treated periodontitis patients, with a clear distinction between intact and reduced periodontium.
  • - There are two main types of gingival diseases: non-dental plaque biofilm-induced diseases, which don't resolve with plaque removal, and dental plaque-induced gingivitis, which can be influenced by both local and systemic factors.
  • - Even treated periodontitis patients can experience a heightened risk of recurrent disease, making it essential for ongoing monitoring and risk assessment to prevent further complications.
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Article Synopsis
  • - Periodontal health is characterized by the absence of visible inflammation and can occur in healthy gums as well as in patients who have had past gum disease but are now stable; however, those with a history of periodontitis are at risk for recurrence and need ongoing monitoring.
  • - Gingival diseases are categorized into two main types: non-dental plaque biofilm-induced diseases, which are not caused by plaque and usually don't improve with plaque removal, and dental plaque-induced gingivitis, which is influenced by both local and systemic factors.
  • - Effective management of gingival health involves identifying and addressing both types of gingival diseases and requires regular assessments, particularly for individuals with a history of periodontal disease to prevent potential relapse.
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Oral melanoma and other pigmentations: when to biopsy?

J Eur Acad Dermatol Venereol

February 2018

Dermatology, Department of Experimental Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

Article Synopsis
  • Oral pigmentations (OPs) are often overlooked, yet they are crucial for diagnosing oral melanoma and identifying systemic diseases through careful oral cavity examinations.
  • OPs are categorized into two main types: focal (like amalgam tattoo and melanocytic nevi) and diffuse (such as physiological pigmentations and drug-induced hyperpigmentations).
  • The text emphasizes the importance of distinguishing between common OPs and oral mucosal melanoma (OMM), highlighting lesions that may require biopsy or need to be regularly monitored.
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Gingival Pigmentation Affected by Smoking among Different Age Groups: A Quantitative Analysis of Gingival Pigmentation Using Clinical Oral Photographs.

Int J Environ Res Public Health

August 2017

Section of Geriatric Dentistry, Department of General Dentistry, Fukuoka Dental College, Fukuoka 814-0193, Japan.

Article Synopsis
  • The study aimed to explore age-related differences in gingival pigmentation due to smoking among a young population, which has not been thoroughly researched.
  • Participants, aged 19 to 79, were analyzed using photographs and categorized into 10-year age groups, revealing that those in their 30s had the most significant gingival pigmentation.
  • It was found that smoking cessation had a minimal effect on gingival pigmentation in individuals in their 20s, indicating that younger smokers experience more pronounced pigmentation changes than older adults, highlighting the need for targeted anti-smoking education for younger populations.
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