4 results match your criteria: "Smilow Cancer Hospital at St. Francis[Affiliation]"
Bing-Neel syndrome (BNS) remains a rare complication of Waldenstrom Macroglobulinemia. Given the paucity of this disease, treatment guidelines are based on small clinical trials with limited participants. Here, we present a case of primary CNS diffuse large B-cell lymphoma masqueraded as BNS that developed while on ibrutinib therapy.
View Article and Find Full Text PDFJ Oncol Pharm Pract
April 2021
Department of Hematology and Oncology, Smilow Cancer Hospital at St. Francis, Hartford, CT, USA.
Introduction: Immune-checkpoint inhibitors have become an increasingly popular form of systemic therapy for cancer treatment. Their use has proven to be so effective that certain regimens have gained approval as first-line therapy for various solid tumor types. The most common and well-studied forms of immunotherapy include agents that target cytotoxic T-lymphocyte antigen-4, programmed death-1, and programmed death ligand-1.
View Article and Find Full Text PDFCase Rep Hematol
April 2020
Department of Hematology and Oncology, Smilow Cancer Hospital at St. Francis, Hartford, CT, USA.
Primary bone lymphoma (PBL) is a subtype of lymphoma that exclusively affects skeletal tissue. Despite the relatively common involvement of skeletal structures as a manifestation of non-Hodgkin's lymphoma (NHL), primary and exclusive involvement of the skeletal system is rare. The prevalence of PBL is estimated to be 3-7% amongst primary bone tumors and less than 2% amongst all lymphomas in adults.
View Article and Find Full Text PDFCase Rep Oncol Med
July 2019
Department of Medical Oncology, Smilow Cancer Hospital at St. Francis, Hartford, CT, USA.
The advent of checkpoint inhibitor therapy in medical oncology has led to an increase in hospitalizations for immune-related adverse effects. Severe colitis has been reported in approximately 5% of patients treated with cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) inhibitors, such as ipilimumab. Standard management for those with severe colitis includes administration of systemic corticosteroids with the reservation of antitumor necrosis factor (anti-TNF) therapy, such as infliximab, if there has been no improvement.
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