Longitudinal Assessment of Cognitive Function in Survivors of Testicular Germ Cell Tumor.

Background And Objective: Survivors of testicular germ cell tumor (TGCT) may experience long-term cognitive changes. The aim of our prospective study was to longitudinally assess cognitive function among TGCT survivors to identify potential lasting cognitive changes over a period of 5 yr.

Methods: TGCT survivors (n = 151) completed Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) questionnaires annually, with median time to first follow-up visit (FUV) of 8 (range 4-24) yr since completion of treatment.

ECHINOCOCCUS MULTILOCULARIS IN NEW YORK WILDLIFE: DISTRIBUTION AND GENETIC DIVERSITY OF AN EMERGING PATHOGEN.

Echinococcus is a genus of cestode parasites of paramount veterinary and medical importance globally. Two species, Echinococcus granulosus sensu lato and Echinococcus multilocularis, are endemic to North America and are the etiologic agents of cystic echinococcosis and alveolar echinococcosis, respectively. North America is currently experiencing an epidemiological shift in the state of transmission, distribution, and prevalence of E.

Temperature-dependent sleep patterns in Drosophila.

Sleep is a fundamental physiological process conserved through evolution, from worms to humans. Understanding how temperature influences sleep is essential for comprehending the complexities of animal behavior, physiology, and their adaptations to thermal environments. This study explores the impact of temperature on sleep behavior and patterns in Drosophila melanogaster.

As, Cd, Hg, and Pb Biological Concentrations and Anthropometry in Slovak Adolescents.

Anthropometry provides a non-invasive technique for evaluating growth and obesity and serves as an indicator of health status. This cross-sectional study aims to investigate the association of internal arsenic (As), cadmium (Cd), total mercury (THg), methylmercury (MeHg), and lead (Pb) exposure with anthropometric parameters, including obesity, in adolescents. Participants (N = 320) were children aged 10-14 years (mean 11.

Safety and Efficacy of BioMime Sirolimus-Eluting Stent System in All-Comers Real-World Population With Coronary Artery Stenosis: MILES Global Registry.

Background: This study evaluated the safety and efficacy of BioMime sirolimus-eluting stent (SES) system, with an ultra-low strut thickness (65 µm), in real-world all-comers population with coronary artery stenosis (CAD).

Methods: This was a post-marketing, multicenter, single-arm, observational clinical registry among patients undergoing intervention for CAD. Patients were clinically followed up at 1, 9, 12, and 24 months after the index percutaneous coronary intervention.

Exploring Anisotropy Contributions in Mn Co FeO Ferrite Nanoparticles for Biomedical Applications.

Designing well-defined magnetic nanomaterials is crucial for various applications, and it demands a comprehensive understanding of their magnetic properties at the microscopic level. In this study, we investigate the contributions to the total anisotropy of Mn/Co mixed spinel nanoparticles. By employing neutron measurements sensitive to the spatially resolved surface anisotropy with sub-Å space resolution, we reveal an additional contribution to the anisotropy constant arising from shape anisotropy and interparticle interactions.

Association between climate change and patient health outcomes: a mixed-methods systematic review.

Introduction: Climate change poses significant threats to the environment, biodiversity, and socioeconomic stability worldwide. Its impact on human health, particularly within healthcare systems, is growing in concern. Nurses, as front-line healthcare workers, play a crucial role in addressing climate-related health risks.

Pharmacist-led interventions for vascular surgery patients: a prospective study on reducing drug-related problems.

Background: Vascular surgery patients are at a high risk of polypharmacy and drug-related problems. Only a limited number of studies have explored the impact of hospital pharmacists being members of a multidisciplinary team in the care of vascular surgery patients. The clinical study (Trial Registration Number NCT04930302, 16 June 2021) aimed to assess the impact of pharmacist-led interventions on the prevalence of drug-related problems among patients hospitalised at the vascular surgery department.

Report of the First ONTOX Hackathon: Hack to Save Lives and Avoid Animal Suffering. The Use of Artificial Intelligence in Toxicology - A Potential Driver for Reducing/Replacing Laboratory Animals in the Future.

The first ONTOX Hackathon of the EU Horizon 2020-funded ONTOX project was held on 21-23 April 2024 in Utrecht, The Netherlands (https://ontox-project.eu/hackathon/). This participatory event aimed to collectively advance innovation for human safety through the use of Artificial Intelligence (AI), and hence significantly reduce reliance on animal-based testing.

Vavro Šrobár: Slovak politician and publicist as a medical doctor involved (also) in the history of medicine.

Vavro Šrobár was a prominent political figure in East-Central Europe. He played a pivotal role in the establishment and development of the First Czechoslovak Republic, which emerged following the dissolution of the Austro-Hungarian Empire. He was the first Minister to exercise full administrative authority in overseeing the Provisional Government of Slovakia, and throughout his career, including until the end of his life, he held several significant political positions, such as Minister of Public Health and Physical Education, Minister of Unification, Minister of Education and National Enlightenment, and Minister of Finance.

Vacuum-Nitrogen Assisted (VANS) Topotactical Deintercalation for Extremely Fast Production of Functionalized Silicene Nanosheets.

Silicene, the analog of graphene composed of silicon atoms arranged in a honeycomb lattice, has garnered significant attention due to its unique properties, positioning it as a promising candidate for various applications in electronic devices, photovoltaics, photocatalysis, and biomedicals. While the chemical synthesis of silicene nanosheets has traditionally involved time-spending and expensive- methods, this study introduces a rapid vacuum/nitrogen cycle assisted (VANS) protocol that dramatically speeds up the production of silicene. The strategic implementation of vacuum/nitrogen cycles provides the efficient removal of the generated hydrogen, boosting the overall reaction kinetics while maintaining inert reaction conditions to prevent oxidation.

The Role of COVID-19 in Excess Mortality in Slovakia: A Novel Approach Based on Healthcare Billing Records.

Objectives: Propose a methodology to identify COVID-19 associated deaths using healthcare billing records and evaluate its effectiveness by comparing the results with excess mortality data from 2020 to 2022 and confirmed COVID-19 deaths.

Methods: A retrospective quantitative analysis was conducted by merging healthcare billing records with cause of death data. The term "COVID-19 associated death" was defined as any death occurring within a defined timeframe following a confirmed contact with COVID-19.

Adolescents' Wellbeing at School: What Helps and What Hinders From Feeling Safe and Satisfied?

Objectives: The aim of this qualitative study was to identify the main factors that help and hinder adolescents' wellbeing at school using their perspectives and experiences.

Methods: We used data from 45 adolescents in the first year of high school in Slovakia (mean age = 14.98; 22.

Gingiva as immunological protection of the periodontium. Minireview.

Objectives: The anti-infective, predominantly antibacterial protection of the periodontium has been well-mapped in its various inflammatory diseases, especially in different clinical forms of gingivitis and periodontitis. In various inflammatory periodontal diseases, many immunocompetent cells and substances have been identified in periodontal structures, including the gingiva, which implement and ensure this anti-inflammatory response. There is ample evidence that in many clinical forms of gingivitis and periodontitis, these immunological-defensive reactions occur in the gingival tissue.

P , T -odd effects in YbCu, YbAg, and YbAu.

In this work, the molecular enhancement factors of the P,T-odd interactions involving the electron electric dipole moment (Wd) and the scalar-pseudoscalar nucleon-electron couplings (Ws) are computed for the ground state of the bimetallic molecules YbCu, YbAg, and YbAu. These systems offer a promising avenue for creating cold molecules by associating laser-cooled atoms. The relativistic coupled-cluster approach is used in the calculations, and a thorough uncertainty analysis is performed to give accurate and reliable uncertainties to the obtained values.

Three Decades of Adolescent Health: Unveiling Global Trends Across 41 Countries in Psychological and Somatic Complaints (1994-2022).

Objectives: This study examined (non-)monotonic time trends in psychological and somatic complaints among adolescents, along with gender differences.

Methods: Repeated cross-sectional Health Behaviour in School-aged Children (HBSC) data from 1994 to 2022 covering 15-year-old adolescents from 41 countries (N = 470,797) were analysed. Three polynomial logistic regression models (linear, quadratic, cubic) were tested for best fit, including separate analyses by gender and health complaints dimension.

Detection of Access Point Spoofing in the Wi-Fi Fingerprinting Based Positioning.

Indoor positioning based on Wi-Fi signals has gained a lot of attention lately. There are many advantages related to the use of Wi-Fi signals for positioning, including the availability of Wi-Fi access points in indoor environments and the integration of Wi-Fi transceivers into consumer devices. However, since Wi-Fi uses an unlicensed spectrum, anyone can create their own access points.

Online Calibration of Inertial Sensors Based on Error Backpropagation.

Global satellite navigation systems (GNSSs) are the most-used technology for the localization of vehicles in the outdoor environment, but in the case of a densely built-up area or during passage through a tunnel, the satellite signal is not available or has poor quality. Inertial navigation systems (INSs) allow localization dead reckoning, but they have an integration error that grows over time. Inexpensive inertial measurement units (IMUs) are subject to thermal-dependent error and must be calibrated almost continuously.