66 results match your criteria: "Skull Base Petrous Apex Infection"
Minimally Invasive Transnasal Approach to the Anteromedial Temporal Fossa and Lateral Sphenoid Using a Novel Landmark between Periorbita and Periosteum of the Pterygopalatine Fossa: A Cadaveric Study.
J Neurol Surg B Skull Base
October 2024
Department of Otolaryngology, School of Medicine, The University of North Carolina, Chapel Hill, North Carolina.
Article Synopsis
- The anteromedial temporal region and lateral wall of the sphenoid host various pathologies like trigeminal schwannoma and malignancy, posing surgical challenges due to the need to remove turbinates and nasolacrimal ducts, leading to complications.
- A new anatomical landmark called the inferolateral periorbital periosteal line (ILPPL) has been identified, allowing for a less invasive surgical approach without sacrificing critical structures.
- By using a multiangled approach to the ILPPL, surgeons can effectively reach the targeted areas while preserving physiological functions, making the procedure safer and more efficient.
Carbon-ion Radiotherapy for Inoperable Solitary Fibrous Tumor of the Skull Base: A Case Report.
In Vivo
March 2023
Department of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Japan.
Background/aim: The curative treatment for solitary fibrous tumors (SFTs) consists of surgery. However, surgery for SFTs in the skull base is difficult due to the anatomy and curative surgery may not be possible. Carbon-ion radiotherapy (C-ion RT) might be useful in the treatment of inoperable SFTs in the skull base because of its biological and physical nature.
View Article and Find Full Text PDFA Rare Complication of Chronic Otitis Media: Central Skull Base Osteomyelitis Managed With Combined Endoscopic Transmastoid and Transsphenoidal Debridement.
Otol Neurotol
March 2022
Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.
Objective: This report describes a case of otogenic central skull base osteomyelitis (CSBO) requiring complex surgical intervention and reviews the literature on management of this entity.
Patient: A 76-year-old man presented with a nearly 20-year history of chronic otomastoiditis and cholesteatoma with ultimate progression to severe CSBO with involvement of the petrous apex, clivus, and craniocervical junction.
Interventions: CSBO was managed with culture-directed antibiotic therapy, hyperbaric oxygen, and surgical intervention including serial combined endoscopic transmastoid and transsphenoidal debridements.
Retrospective analysis of massive epistaxis and pseudoaneurysms in nasopharyngeal carcinoma after radiotherapy.
Eur Arch Otorhinolaryngol
June 2022
Department of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital of Nanchang University, No.17 Yongwaizheng Street, Nanchang, 330006, Jiangxi, China.
Article Synopsis
- The article examines the link between massive nosebleeds (epistaxis) and the development of pseudoaneurysms in patients with nasopharyngeal carcinoma (NPC) who have undergone radiotherapy.
- A review of 21 patients showed that most had skull base damage and tumor recurrence, with many experiencing pseudoaneurysms primarily in the internal and external carotid arteries.
- Despite successful endovascular treatment in most cases, there were notable fatalities, highlighting pseudoaneurysm as a serious complication after radiotherapy for NPC.
Skull base osteomyelitis: Comprehensive analysis and a new clinicoradiological classification system.
Auris Nasus Larynx
October 2021
Faculty of Medicine, Department of Otorhinolaryngology, Hacettepe University, Sıhhiye, Ankara Turkey.
Article Synopsis
- Skull base osteomyelitis (SBO) is a serious condition mainly affecting diabetic or immunocompromised individuals, leading to significant health risks.
- A study analyzed 32 patients treated at a care center, developing a new classification system that combines MRI findings, cranial nerve dysfunction, and clinical grading.
- Results indicated that higher clinical grades correlate with worse survival outcomes, while surgery didn't affect discharge status; the proposed classification could help predict patient prognosis effectively.
[Analysis on endoscopic endonasal approach combined with the frontotemporal orbitozygomatic approach under the microscope for skull base tumor with intra and extra-cranial involvement].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2021
Department of Otorhinolaryngology Head and Neck Surgery, Tianjin Huanhu Hospital, Tianjin 300350, China.
To evaluate the application of combination use of endoscopic endonasal approach combined with the frontotemporal orbitozygomatic approach microscopically in skull base tumor with intra and extra-cranial involvement. A total of 7 patients (4 males and 3 females, aging from 27 to 65 years old, with a medium age of 48) undergone complicated skull base surgeries via endoscopic endonasal approach combined with the frontotemporal orbitozygomatic approach microscopically from May 2016 to January 2018 were reviewed respectively. The patients included 2 cases of recurrent invasive pituitary adenoma, 3 cases of basal skull meningiomas, 1 case of clivus chondrosarcoma, and 1 case of recurrent nasopharyngeal carcinoma.
View Article and Find Full Text PDFMorphometric Study of the Posterior Fossa: Identification of Practical Parameters for Tailored Selection of Surgical Routes to the Petroclival Region.
J Neurol Surg B Skull Base
February 2022
Department of Neurological Surgery, University of Louisville School of Medicine, Louisville, Kentucky, United States.
Article Synopsis
- The petroclival region is a critical area of the skull base that can contain various pathologies and is important for accessing the petroclival junction and cerebellopontine angle for surgeries.
- This study assessed the anatomical features of this region using CT scans from 90 patients aged 18 and older, measuring factors like clival length, angles, and volumes of specific corridors.
- Findings showed significant variability in anatomy, suggesting that preoperative measurements can aid surgeons in planning the best surgical approach based on individual patient anatomy.
Transmastoid and Transtemporal Drainage of Petrous Apicitis with Otitis Media.
Ann Otol Rhinol Laryngol
March 2021
Department of Otolaryngology-Head and Neck Surgery, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Article Synopsis
- Petrous apicitis (PA) is a serious bone infection in the ear area, with classical symptoms becoming rare due to timely antibiotic intervention.
- A case study showed successful treatment of PA through initial intravenous antibiotics followed by a specific surgical drainage method after a comprehensive evaluation.
- The discussion suggests that the middle cranial fossa approach is preferable when accessing difficult areas of the infection compared to other surgical options.
Prediction of skull base osteomyelitis in necrotising otitis externa with diffusion-weighted imaging.
J Laryngol Otol
May 2020
Department of Diagnostic Radiology, Mansoura University Faculty of Medicine, Mansoura, Egypt.
Article Synopsis
- The study aimed to predict skull base osteomyelitis in patients with necrotizing otitis externa using diffusion-weighted imaging.
- A retrospective analysis of 25 patients showed significant differences in apparent diffusion coefficient values between those with and without skull base osteomyelitis.
- The optimal diffusion coefficient threshold for predicting osteomyelitis was identified, demonstrating high accuracy, sensitivity, and specificity, indicating its effectiveness as a non-invasive diagnostic tool.
Hybrid antero-lateral transcondylar approach to the clivus: a laboratory investigation and case illustration.
Acta Neurochir (Wien)
June 2020
Department of Neurosurgery, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Université de Paris, 2 rue Ambroise Pare, 75010, Paris, France.
Article Synopsis
Skull Base Osteomyelitis Complicated by Petrous Internal Carotid Artery Blowout.
Ear Nose Throat J
September 2021
Division of Otolaryngology, Brigham and Women's Hospital, 1811Harvard Medical School, Boston, MA, USA.
Article Synopsis
- Skull base osteomyelitis (SBO) is a severe infection primarily affecting older diabetics, particularly in the external auditory canal and skull base.
- Diagnosis involves a mix of clinical, lab, and imaging tests, while treatment usually consists of long-term antibiotics, and sometimes surgery if necessary.
- A unique case of a 77-year-old woman illustrated that SBO can lead to a rare and dangerous complication where the internal carotid artery ruptures, resulting in severe bleeding from the ear, emphasizing the need for clinicians to consider this risk in similar cases.
Severe Daily Headache as an Uncommon Manifestation of Widespread Skull Base Osteomyelitis.
Case Rep Neurol
May 2019
Department of Neurology, Leiden University Medical Centre/Haga Hospital, Leiden, The Netherlands.
Article Synopsis
- - A 70-year-old man with diabetes experienced severe chronic headaches, which were diagnosed as central skull base osteomyelitis, a rare complication of ear infections.
- - Imaging techniques revealed a hypermetabolic mass affecting various bones around the skull base, indicating significant damage and invasion.
- - The case highlights the importance of thorough clinical and imaging evaluations for diabetic or immunocompromised patients presenting with chronic headaches and ear pain, to consider the possibility of skull base osteomyelitis.
Insidious onset of headache, diplopia and Horner's syndrome: a rare case of petrous bone osteomyelitis.
BMJ Case Rep
September 2019
Diabetes and Endocrine, Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool, UK.
Article Synopsis
- - An 88-year-old woman experienced worsening unilateral headaches and double vision, leading to an evaluation that revealed neurological signs including Horner's syndrome and sixth cranial nerve palsy.
- - Diagnostic imaging, specifically an MRI of the neck, showed changes in the petrous bone that confirmed the presence of skull base osteomyelitis.
- - The case emphasizes that skull base osteomyelitis should be considered when patients present with subacute inflammatory markers and signs related to cranial nerves.
CT and clinical prognostic factors in Bell's palsy: A study of 56 cases.
Clin Otolaryngol
September 2019
ENT Department, Pitié-Salpêtrière University Hospital, Paris Greater University Hospitals, Paris, France.
Extensive Skull Base Osteomyelitis Secondary to Malignant Otitis Externa.
J Int Adv Otol
December 2019
Infectious Disease Unit, University Hospital of Pisa, Pisa, Italy.
Article Synopsis
- Skull base osteomyelitis is a serious condition that can develop from malignant otitis externa, impacting the marrow of specific skull bones.
- A 76-year-old man experienced this complication after initially presenting with right-sided malignant otitis externa, which progressively worsened despite antibiotics.
- The condition remarkably advanced over three years, affecting not only the skull base but also extending to the opposite side and the cervical vertebrae.
Cochlear Implantation in Chronic Otitis Media With Cholesteatoma and Open Cavities: Long-term Surgical Outcomes.
Otol Neurotol
January 2018
Department of Otology and Skull Base Surgery, Gruppo Otologico, Piacenza, Rome, Italy.
Article Synopsis
- The study evaluated long-term surgical outcomes of cochlear implantation (CI) in patients with chronic otitis media (COM) and cholesteatoma using subtotal petrosectomy (STP), involving a review of 35 cases.
- Results indicated a mean follow-up of over 7 years, with 11% experiencing device explantation due to issues like extrusion and infection, though most were reimplantable.
- The findings suggest that CI is feasible for these patients, and while the risk of residual cholesteatoma post-surgery is low, the risk of device explantation is higher compared to standard procedures.
Pediatric Langerhans cell histiocytosis of the lateral skull base.
Int J Pediatr Otorhinolaryngol
August 2017
Department of Otolaryngology - Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:
Article Synopsis
- The study aims to describe pediatric patients with Langerhans cell histiocytosis (LCH) affecting the temporal bone, focusing on their symptoms, imaging findings, treatments, and outcomes.
- A retrospective analysis of 14 patients revealed common symptoms like scalp lesions and ear infections, with the majority requiring chemotherapy; some patients experienced hearing loss and disease recurrence.
- The findings suggest that LCH presents variably in children, indicating that surgical removal has limited benefits, and ongoing follow-up is vital to manage potential complications and disease progression.
Severe skull base osteomyelitis caused by Pseudomonas aeruginosa with successful outcome after prolonged outpatient therapy with continuous infusion of ceftazidime and oral ciprofloxacin: a case report.
J Med Case Rep
February 2017
Infectious Diseases Unit, Hospital General Universitario de Elche, Camino de la Almazara, 11, 03203, Elche, Alicante, Spain.
Article Synopsis
- Skull base osteomyelitis is a rare and serious condition primarily affecting diabetic and immunocompromised males, commonly caused by Pseudomonas aeruginosa, with a high mortality rate and a lack of consensus on treatment methods.
- A case study of a 69-year-old man revealed severe symptoms like dysphagia and cranial nerve palsy, leading to a diagnosis of the disease after imaging and biopsy confirmed the presence of Pseudomonas aeruginosa.
- The patient was effectively treated with prolonged outpatient antibiotic therapy, including continuous infusion of ceftazidime and oral ciprofloxacin, resulting in significant clinical and radiological improvement.
Generalized lymphatic anomaly is a multifocal lymphatic malformation that affects the skin, thoracic viscera, and bones. A 3year-old Japanese boy presented with right facial palsy due to cystic tumors in the ipsilateral petrous bone. Pericardial effusion had been found incidentally and generalized lymphatic anomaly had been diagnosed by pericardial biopsy.
View Article and Find Full Text PDF[Apical petrositis, osteomyelitis of the base of the skull bones and of the first cervical vertebra in a 5 year-old children following chicken pox].
Vestn Otorinolaringol
June 2016
Pirogov Russian National Research Medical University, Moscow, Russia, 117997.
This publication was designed to describe a rare case of development of apicalpetrositis in a child presenting with acute otitis mediafollowing chicken pox experienced in the preceding period. We carried out the study with the use of computed tomography (CT) that demonstrated destruction of the temporal bone, bones of the base of the skull and of the first cervical vertebra. The treatment strategy chosen for the management of this condition that included antibiotic therapy and expectant observation proved justified and can be recommended as an algorithm of choice taking into consideration the difficulty of surgical approach to the apex of the petrous pyramid.
View Article and Find Full Text PDFGruber, Gradenigo, Dorello, and Vail: key personalities in the historical evolution and modern-day understanding of Dorello's canal.
J Neurosurg
January 2016
Departments of 1 Neurological Surgery and.
Article Synopsis
- Primo Dorello, a young anatomist in early 20th century Rome, studied abducent nerve palsy linked to middle ear infections and discovered the nerve's vulnerability in a narrow canal, sparking a scientific debate with established otologist Giuseppe Gradenigo.
- Their correspondence culminated in 1909, when Dorello effectively countered Gradenigo's criticisms, leading to Gradenigo's eventual change of opinion.
- Today, Dorello's canal is crucial in skull base surgery, acknowledging both Dorello and Gradenigo's contributions while also recognizing earlier work by Austrian anatomist Wenzel Leopold.
Gradenigo's syndrome as first presentation of solitary osseous plasmacytoma of the petrous apex.
Arch Iran Med
July 2014
Department of Neurosurgery, Arad Hospital, Tehran, Iran.
Article Synopsis
- Plasma cell tumors at the skull base are uncommon, and solitary osseous plasmacytomas without multiple myeloma are very rare in neurosurgery.
- A case study details a 46-year-old man with Gradenigo's syndrome, showing symptoms like left abducens nerve palsy due to a plasmacytoma in the left petrous apex.
- Following subtotal resection and radiation treatment, the patient showed improvement in his symptoms and remained symptom-free four years later, with no signs of cancer recurrence or progression.
Skull base osteomyelitis in otitis externa: The utility of triphasic and single photon emission computed tomography/computed tomography bone scintigraphy.
Indian J Nucl Med
April 2013
Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- Skull base osteomyelitis (SBO) is a serious infection that can develop from severe otitis externa, making it challenging to diagnose without proper imaging techniques.
- This study analyzed 20 patients with suspected SBO using three phase bone scintigraphy (TPBS) and SPECT/CT, correlating results with clinical and lab findings.
- The findings showed that TPBS and SPECT/CT were effective in detecting SBO, with TPBS being positive for SBO in half of the patients, and influencing treatment decisions in some cases.
The role of subtotal petrosectomy in cochlear implant surgery--a report of 32 cases and review on indications.
Otol Neurotol
August 2013
Department of Otorhinolaryngology-Head and Neck Surgery, Cochlear Implant Center Northern Netherlands, University Medical Center Groningen, University of Groningen, The Netherlands.
Objective: To report and review 32 cases of subtotal petrosectomy (SP) in cochlear implant (CI) surgery and to define the indications and contraindications for this procedure.
Study Design: Retrospective case review + case reports.
Setting: Tertiary skull base center.
Aspergillus petrous apicitis associated with cerebral and peritubular abscesses in an immunocompetent man.
J Laryngol Otol
April 2013
Department of Otolaryngology Head and Neck Surgery, Royal Preston Hospital, UK.
Article Synopsis
- Petrous apex aspergillosis is a rare, serious condition with only four previous cases reported, and it often has non-specific symptoms that delay diagnosis.
- The case study details a 72-year-old man who experienced severe symptoms from chronic ear issues, leading to the discovery of fungal infections in the petrous apex, temporal lobe, and nasopharynx.
- The patient successfully recovered with voriconazole treatment, emphasizing the importance of tissue biopsy for accurate diagnosis and the effectiveness of antifungal therapy over surgical options.