Assessment of a colposcopic scoring system (Swedescore) to reduce the number of cervical biopsies: a protocol for a clinical multicentre non-randomised intervention study in Denmark.

Introduction: Colposcopy is a standard procedure for evaluating cervical abnormalities and collecting cervical biopsies. The procedure is associated with intra- and inter-observer variation. A colposcopic scoring system, Swedescore, has been designed to standardise and facilitate colposcopy training.

Sex-mediated effects of transglutaminase 2 inhibition on endothelial function in human resistance arteries from diabetic and non-diabetic patients.

Transglutaminase 2 (TG2) is an enzyme with multiple conformations. In its open conformation, TG2 exhibits transamidase activity linked to fibrosis, arterial remodeling, and endothelial dysfunction, a process enhanced by high glucose in endothelial cells. However, the closed conformation of TG2 contributes to transmembrane signaling and nitric oxide (NO)-dependent vasorelaxation.

[Christmas article: Point-of-care test of optimal meat structure in Danish Pork Roasts - a prospective observational study].

Introduction: Pork Roast is an important part of the Danish holidays. The precise cooking of the pork roast is a controversial debate, which has been going on for decades. Newer techniques such as sous vide have been gaining popularity, but the optimal pork roast is yet to be determined.

[Christmas article: Maximum bladder capacity at an anesthesiology department’s Christmas party].

Introduction: Christmas parties, a longstanding Danish tradition, became festive occasions in the 1960s. This study examines if healthcare professionals, especially doctors and nurses, have larger bladder capacities than the general population, as they often delay restroom breaks.

Methods: At the North Zealand University Hospital Department of Anesthesiology's 2023 Christmas party, participants delayed urination until a strong urge occurred.

[Christmas article: collisions between roe deer and ambulances].

Introduction: Preoperative templating in hip arthroplasty surgery is crucial for accurate implant selection and reducing postoperative complications. This study examines whether there is a correlation between femoral head size and shoe size, with the aim of simplifying the preoperative planning process.

Methods: A total of 14 patients had their shoe size and femoral head size measured.

[Christmas article: Christmas article: The professors take up the master's program at Rigshospitalet].

Caricatures highlight personal characteristics. The caricature drawing of the four prominent professors from the transition from the Royal Frederik's Hospital to Rigshospitalet, Copenhagen in 1910, shows the dominant surgeon Niels Thorkild Rovsing (1862-1927), who takes up half of the drawing; the reserved organizationally interested physician Knud Helge Faber (1862-1956) in the middle; the thoughtful surgeon Oscar Thorvald Bloch (1847-1926), and the somewhat isolated physician Hans Christian Joachim Gram (1853-1938), who became known for his staining method to separate Gram-positive from Gram-negative bacteria.

[Christmas article: Importance of seniority and daily variation for the flattening of academic medical language].

Introduction: In the medical community Greek and Latin form a cornerstone of our daily professional communication. The use of correct terminology is under pressure, although the extent of incorrect terminology is unknown, particularly regarding the Greek suffix »-itis«, which indicates inflammation. It has been observed that the correct »-itis« suffix is being reduced to »-it« (e.

[Christmas article: collisions between roe deer and ambulances].

Introduction: Due to the Danish fauna, reindeer are not immediately available should Santa Claus need to replace his reindeer while traveling across Denmark with Christmas gifts. Instead, Santa Claus should rely on roe deer, which are predominant in Denmark. However, the population of roe deer may be threatened by collisions between ambulances and roe deer.

[Christmas article: From diagnosis to delicacy: using MR and DXA scanners to roast Christmas duck].

Introduction: The holiday season poses a unique challenge for hospital staff, especially on night shifts, who must juggle their duties with preparing a festive Christmas meal. This study investigates the novel idea of using hospital MRI scanners to cook duck breasts during shifts. MRI scanners, which use magnetic fields and radiofrequency (RF) pulses for imaging, also generate heat, potentially suitable for cooking.

[Christmas article: A little booze to warm you up - true or false? A thermographic Christmas study].

Introduction: In December, it is common to enjoy mulled wine, often believed to warm the body. While alcohol can cause peripheral vasodilation, it remains unclear whether it truly increases body warmth or is merely a subjective sensation. This study aimed to evaluate the warming effect of mulled wine using thermography.

[Prolonged epistaxis symptom of nasopharynx carcinoma in a child].

This case report presents a ten-year-old boy with recurrent nosebleeds (epistaxis) over an extended period. In addition, he showed signs of slowed weight gain and developed symptoms such as snoring and sweating during sleep. Rhinoscopy revealed a mass in the nasopharynx, and further tests confirmed the presence of an Epstein-Barr Virus-positive nasopharyngeal carcinoma.

[Melanoma in pregnancy].

The melanoma incidence is rising. Among pregnant women, melanoma is one of the most common cancers accounting for approximately 30% of all cancers. Timely diagnosis is critical, but management of pregnant women with melanoma lacks international consensus, and uncertainties may arise.

[Misinterpretation of bulking depots as tumours].

Stress urinary incontinence can be treated surgically with bulking agents. This is a report of two cases: I. A 42-year-old woman had successful bulking in 2007, in 2023 there was a urological assessment due to an incidental cystic process near the urethra, and bulking agents were resected leading to severe incontinence due to sphincter insufficiency.

[Spontaneous coronary artery dissection].

Spontaneous coronary artery dissection (SCAD) presents a life-threatening condition, prevalent among young women, comprising up to 35% of acute coronary syndrome cases. It involves sudden, trauma-free splitting of coronary artery walls, reducing blood flow and mimicking symptoms of acute myocardial infarction. Despite recent attention, treatment remains debated.

Clinical characteristics and diagnostic accuracy of preliminary diagnoses in adults with infections in Danish emergency departments: a multicentre combined cross-sectional and diagnostic study.

Objective: Rapid and accurate infection diagnosis is a prerequisite for appropriate antibiotic prescriptions in an ED. Accurately diagnosing acute infections can be difficult due to nonspecific symptoms and limitations of diagnostic testing. The accuracy of preliminary diagnoses, established on the initial clinical assessment, depends on a physician's skills and knowledge.

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Psoriasis is a common chronic inflammatory skin disease with several clinical subtypes. Recent discoveries in the genetics and immunology of the disease, particularly in plaque psoriasis, have revolutionised the treatment of patients with psoriasis. An understanding of the differences in genetics and immunology between different psoriasis subtypes is emerging.

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This review underscores that psoriasis can manifest in infancy, negatively impacting the quality of life of children and their families. It often presents as minor, less pruritic plaques with subtle characteristics. Pediatric psoriasis is associated with an increased risk of arthritis, metabolic disorders, and psychological conditions, necessitating regular screenings.

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Psoriasis is a chronic skin disease for which there is no cure. However, the systemic treatment of psoriasis has undergone a revolution over the last few decades and now offers many different options. With more effective treatments available, the endpoints for successful treatment have also changed.

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Patiens with psoriasis and mild to moderate skin disease can be treated with topical agents. This review finds that the most effective topical treatment is calcipotriol and betamethasone combination formulations. Pure topical corticosteroids continue to have a role in the treatment of psoriasis, as they are available in many strengths and formulations that facilitate ease of use.