1 results match your criteria: "Sixth People's Hospital Affiliated Shanghai Jiao Tong University 600 Yi-Shan Road[Affiliation]"
Overexpression of NDC80 is correlated with prognosis of pancreatic cancer and regulates cell proliferation.
Am J Cancer Res
July 2015
Department of General Surgery, Sixth People's Hospital Affiliated Shanghai Jiao Tong University 600 Yi-Shan Road, Shanghai 200233, China.
Aims: NDC80/Hec1, one of four proteins of the outer kinetochore NDC80 complex, is involved in the tumorigenesis of a variety of cancers. In this study, we focused on that NDC80 is overexpressed in human pancreatic cancer and investigates the role of NDC80-knockdown in pancreatic cancer cells proliferation.
Materials And Methods: We determined the expression levels of NDC80 on both mRNA and protein levels in fresh pancreatic cancer tissues and cells by quantitative real-time polymerase chain reaction and immunoblotting, respectively.