73 results match your criteria: "Sixth Hospital of Shanxi Medical University[Affiliation]"
Neurotoxicology
December 2024
Department of Occupational Health, School of Public Health, Shanxi Key Laboratory of Environmental Health Impairment and Prevention, NHC Key Laboratory of Pneumoconiosis, MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, Shanxi Medical University, Taiyuan 030001, China. Electronic address:
Objective: To investigate the interaction between plasma polymetallic exposure and lifestyle factors on cognitive function abnormalities in occupational aluminum workers. The aim is to develop a new occupational health management model that integrates lifestyle behaviors with occupational activities to comprehensively protect the health of these workers.
Method: 476 Participants were recruited from an aluminum factory in Shanxi, China.
Burns
November 2024
Department of Radiology, The Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi Province, China. Electronic address:
BMC Cancer
November 2024
Department of Oncology and Intervention, General hospital of TISCO, The Sixth Hospital of Shanxi Medical University, No.7 Yingxin Street, Jiancaoping District, Taiyuan City, 030003, Shanxi Province, China.
Background: Patients with gastrointestinal cancer have a higher risk of malnutrition and postoperative infection.
Objective: To investigate the nutritional status of patients with gastrointestinal cancers and factors for postoperative infections.
Method: Based on the nutritional risk status, 294 patients with gastrointestinal tumours were divided into a nutritional risk group and a non-nutritional risk group, and the differences between the two groups were compared.
Stroke Vasc Neurol
September 2024
Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, Yingze District Shanxi Province, China
Objectives: Despite the potential spillover effect, the optimal duration of dual antiplatelet therapy for minor stroke within 72 hours of symptom onset is still uncertain.
Methods: Safety and Efficacy of Aspirin-Clopidogrel in Acute Noncardiogenic Minor Ischemic Stroke (National Institutes of Health Stroke Scale (NIHSS) score≤5) is a prospective cohort study involving patients with minor ischaemic stroke within 72 hours of symptom onset. The DAPT group was further categorised into three subgroups: shorter duration (<10 days), short duration (10-21 days) and long duration (>21 days).
Expert Opin Drug Saf
December 2024
Department of Urology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Background: Prostate cancer is one of the most common malignancies in men worldwide, and prostate-specific antigen (PSA) screening is widely used for its early detection. Drug use may affect PSA levels, but the effect for most drugs is currently unknown.
Methods: This study first investigated drugs related to PSA changes through the Food and Drug Administration Adverse Event Reporting System (FAERs) database, and then used a Mendelian randomization (MR) method to explore the causal relationship between specific drugs and PSA changes using a genome-wide association study (GWAS) data.
Heliyon
August 2024
Sixth Hospital of Shanxi Medical University, General Hospital of Tisco, Taiyuan, 030008, China.
Bisphenol A (BPA) is a growing concern as an endocrine-disrupting chemical due to its adverse health effects. However, the association between BPA and sperm quality in adult human males remains unclear. The aim of this study was to assess the daily life exposure level of BPA and analyze its correlation with sperm quality in males.
View Article and Find Full Text PDFEcotoxicol Environ Saf
October 2024
MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention, NHC Key Laboratory of Pneumoconiosis, Department of Occupational Health, School of Public Health, Shanxi Medical University, Shanxi Key Laboratory of Environmental Health Impairment and Prevention, Xinjiannan Road 56, Taiyuan City, Shanxi Province 030001, China. Electronic address:
Club cell secretory protein (CC16) is considered a biological marker indicating lung epithelial and lung permeability. The joint effect of polycyclic aromatic hydrocarbons (PAHs) exposure on CC16 levels and the association between CC16 levels and long-term lung function changes lacks epidemiological evidence. To investigate the effect of PAHs exposure on plasma CC16 levels and the association between CC16 levels and long-term lung function changes, this study enrolled 307 coke oven workers in 2014, measured their baseline concentrations of urinary PAHs metabolites and plasma CC16, with follow-up after nine years.
View Article and Find Full Text PDFMol Neurobiol
September 2024
Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.
Alzheimer's disease (AD) is the leading cause of dementia among the elderly population, posing a significant public health challenge due to limited therapeutic options that merely delay cognitive decline. AD is associated with impaired energy metabolism and reduced neurotrophic signaling. The insulin-like growth factor (IGF) signaling pathway, crucial for central nervous system (CNS) development, metabolism, repair, cognition, and emotion regulation, includes IGF-1, IGF-2, IGF-1R, IGF-2R, insulin receptor (IR), and six insulin-like growth factor binding proteins (IGFBPs).
View Article and Find Full Text PDFJ Atheroscler Thromb
September 2024
Department of Neurology, First Hospital of Shanxi Medical University.
Aim: We aimed to assess the association between non-high-density lipoprotein cholesterol (non-HDL-C) and symptomatic intracranial artery stenosis (sICAS), as well as the impact of non-HDL-C on recurrent vascular events in patients with mild ischemic stroke ( NIHSS score ≤ 5).
Methods: This prospective study was based on data from patients presenting within 72 hours of stroke occurrence. We included patients admitted to 8 Chinese hospitals between September 2019 and November 2021.
PLoS One
July 2024
Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Background: Although liver metabolic dysfunction has been found to potentially elevate susceptibility to cognitive impairment and dementia, there is still insufficient evidence to explore the non-linear association of liver enzymes with cognitive performance. Therefore, we aimed to elucidate the non-linear relationship between liver enzymes and cognitive performance.
Methods: In this cross-sectional study, 2764 individuals aged ≥ 60 who participated in the National Health and Nutrition Survey (NHANES) between 2011 and 2014 were included.
Background: Patent foramen ovale (PFO) has been associated with migraine, cryptogenic stroke (CS), and hypoxemia. However, which examination method is most reliable remains controversial. This study sought to investigate the diagnostic value of contrast-enhanced ultrasonography (cU), including contrast-enhanced transcranial Doppler (cTCD), contrast transthoracic echocardiography (cTTE), and contrast transesophageal echocardiography (cTEE), for PFO; and to determine the best diagnostic strategy.
View Article and Find Full Text PDFChronic Dis Transl Med
June 2024
Department of Occupational Health, School of Public Health, Shanxi Key Laboratory of Environmental Health Impairment and Prevention, MOE Key Laboratory of Coal Environmental Pathogenicity and Prevention Shanxi Medical University Taiyuan Shanxi China.
Neural Regen Res
February 2025
Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, China.
JOURNAL/nrgr/04.03/01300535-202502000-00030/figure1/v/2024-05-28T214302Z/r/image-tiff In patients with Alzheimer's disease, gamma-glutamyl transferase 5 (GGT5) expression has been observed to be downregulated in cerebrovascular endothelial cells. However, the functional role of GGT5 in the development of Alzheimer's disease remains unclear.
View Article and Find Full Text PDFJ Clin Sleep Med
October 2024
Department of Radiology, The Sixth Hospital of Shanxi Medical University (General Hospital of TISCO), Taiyuan, People's Republic of China.
Study Objectives: We assessed possible brain abnormalities in adult patients with moderate and severe obstructive sleep apnea using the mean kurtosis (MK) from diffusion kurtosis imaging and analyzed the correlation between MK and cognitive function.
Methods: A total of 30 patients with moderate or severe obstructive sleep apnea and 30 healthy controls evaluated by the Montreal Cognitive Assessment scale were enrolled. All participants underwent diffusion kurtosis imaging and 3-dimensional T1-weighted imaging on a 3.
Int J Womens Health
March 2024
Reproductive Medicine Center, Shanxi Maternal and Child Health Care Hospital, Taiyuan, People's Republic of China.
Molecules
December 2023
School of Forensic Medicine, Shanxi Medical University, Jinzhong 030600, China.
Faced with rising threats of terrorism, environmental and health risks, achieving sensitive and selective detection of peroxide-based explosives (PEs) has become a global focus. In this study, a turn-on fluorescent probe (BOD) based on benzil (HO-recognition element) and 4,4-difluoro-4-bora-3,4-diaza--indacene (BODIPY) derivative (fluorophore) was developed to sensitively and specifically detect hydrogen peroxide (HO). The synthesized BOD had a very weak fluorescence due to intramolecular donor-excited photo-induced electron transfer (-PET) effect; however, it could emit a strong fluorescence since HO selectively oxidized the benzil moiety and released free BODIPY fluorophore (BOD-COOH).
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2024
Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi 030001, China. Electronic address:
Epidemiological studies from diverse global regions suggest a correlation between the accumulation of aluminum in the brain and the onset of various neurodegenerative diseases, including Alzheimer's disease, of which, neuronal cells death happen. Our previous research has found the potential of aluminum to induce neuronal cell death. A comprehensive exploration of the regulatory pathways influenced by aluminum in neuronal cell death could contribute to the development of strategies aimed at preventing the detrimental impact of aluminum on neuronal cells.
View Article and Find Full Text PDFZhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
December 2023
Institute of Burns, General Hospital of TISCO (the Sixth Hospital of Shanxi Medical University), Taiyuan 030009, China.
To observe the clinical effect of free posterior interosseous artery perforator flap carrying superficial vein for reconstructing severe perioral scar hyperplasia and contracture. The retrospective observational study method was used. From August 2019 to March 2023, 11 patients with severe perioral scar hyperplasia and contracture after severe facial burns who met the inclusion criteria were admitted to General Hospital of TISCO (the Sixth Hospital of Shanxi Medical University).
View Article and Find Full Text PDFZhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi
October 2023
Institute of Burns, General Hospital of TISCO (the Sixth Hospital of Shanxi Medical University), Taiyuan 030009, China.
To explore the effects of low position lateral supramalleolar flap carrying periosteum and proximal leg propeller flap in relay repair of electric burn wounds of forefoot. A retrospective observational study was conducted. From January 2019 to January 2022, 12 patients with electric burn wounds of forefoot meeting the inclusion criteria were admitted to the Sixth Hospital of Shanxi Medical University, including 10 males and 2 females, aged 23-65 years.
View Article and Find Full Text PDFAnn Med
September 2023
Device management and maintenance center, Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Shanxi Tongji Hospital, Taiyuan, China.
Objective: To investigate the differences in the viscoelastic properties between normal trapezius muscles and those in patients with trapezius myofascial pain syndrome (MPS) using real-time shear-wave elastography (SWE).
Materials And Methods: This study included 31 patients with trapezius MPS and 31 volunteers. Sixty-one trapezius muscles (41 and 20 on the affected and non-affected side, respectively) of patients with MPS and 62 normal trapezius muscles in volunteers were assessed.
Hypertens Res
February 2024
Department of Neurology, First Hospital of Shanxi Medical University, No. 85, Jiefang Nan Street, Yingze District, Taiyuan, Shanxi, China.
Not only systolic blood pressure (SBP) but also diastolic blood pressure (DBP) increases the risk of recurrence in the short- or long-term outcomes of stroke. The interaction between DBP and antiplatelet treatment for China stroke patients is unclear. This multicenter, observational cohort study included 2976 minor ischemic stroke patients.
View Article and Find Full Text PDFQuant Imaging Med Surg
August 2023
Department of Ultrasound, Sixth Hospital of Shanxi Medical University, Taiyuan, China.
Background: Myofascial pain syndrome (MPS) is a common cause of neck pain, which is a global public health problem. Because MPS does not present morphological changes within lesioned muscles, there are no imaging diagnostic criteria for this condition. In this study, we evaluate elasticity changes in upper trapezius muscles most frequently involved in cervical MPS using real-time ultrasound shear-wave elastography, and we examine their potential diagnostic value.
View Article and Find Full Text PDFToxicology
August 2023
Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan 030001, China; NHC Key Laboratory of Pneumoconiosis, Ministryof Education, Shanxi medical university, China; Key Laboratory of Coal Environmental Pathogenicity and Prevention, Ministry of Education, Shanxi medical university, China.
Aluminum (Al) is recognized as a neurotoxin. Studies have confirmed that the neurotoxicity induced by Al may be related to tau hyperphosphorylation. Phosphorylated tau is degraded through the ubiquitin-proteasome pathway (UPP), in which the carboxyl terminus of Hsc70-interacting protein (CHIP) plays an important role.
View Article and Find Full Text PDFShock
September 2023
Department of Cardiovascular Medicine, General Hospital of Tisco (Sixth Hospital of Shanxi Medical University), Taiyuan City, China.
Background: Aberrant expression of circular RNAs (circRNAs) has been revealed to have crucial roles in the pathological processes of cardiovascular disease. Here, this study aimed to investigate the role and mechanism of circ_0001379 in hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury to explore the potential action of circ_0001379 in acute myocardial infarction (AMI). Methods: Levels of genes and proteins were examined by quantitative real-time polymerase chain reaction and western blot.
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