1,106 results match your criteria: "Sisli Hamidiye Etfal Training And Research Hospital[Affiliation]"

Lateral Sacral Artery Perforator Flap as a New Option in Myelomeningocele Reconstruction.

Ann Plast Surg

December 2024

Department of Neurosurgery, University of Medical Science, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

Article Synopsis
  • The study investigates the use of lateral sacral artery perforator (LSAP) flaps for reconstructing myelomeningocele, highlighting their potential as a new surgical option.
  • Eleven patients underwent the procedure, with a total of 22 LSAP flaps used; results showed an average operation time of 57 minutes and minimal complications.
  • The authors suggest LSAP flaps could be beneficial for lumbar region defects and recommend them as a viable alternative for reconstructing pressure sores in the kyphotic region.
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Comparative performance of artificial intelligence models in rheumatology board-level questions: evaluating Google Gemini and ChatGPT-4o.

Clin Rheumatol

November 2024

Department of Physical Medicine and Rehabilitation, Kanuni Sultan Süleyman Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Objectives: This study evaluates the performance of AI models, ChatGPT-4o and Google Gemini, in answering rheumatology board-level questions, comparing their effectiveness, reliability, and applicability in clinical practice.

Method: A cross-sectional study was conducted using 420 rheumatology questions from the BoardVitals question bank, excluding 27 visual data questions. Both artificial intelligence models categorized the questions according to difficulty (easy, medium, hard) and answered them.

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Article Synopsis
  • * Among 106 patients, 83 had CN, and those who had the surgery could continue their nivolumab treatment for longer (14.5 months) compared to those who didn't have the surgery (6.7 months).
  • * Overall survival was better for patients with CN (22.9 months) compared to those without it (8.1 months), but the surgery and certain medical scores were important factors for how long they lived.
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The aim of this study was to review the characteristics and classifications of pelvic injuries due to earthquake trauma, to determine the treatment options and outcomes, and to present the experiences of our single trauma center. Sixty patients (23 male, 37 female) who underwent surgical treatment for pelvic ring injuries after the earthquake were analyzed in this study. Demographic data, such as age and gender, operations, and fracture details were recorded.

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Objectives: The aim of the study was to investigate whether retinal neurovascular structural impairment in children with partial biotinidase deficiency (BD) could be detected early via optical coherence tomography (OCT) and OCT angiography (OCTA).

Methods: Eighty patients with partial BD and 80 control cases without any known systemic or ocular diseases were enrolled in this prospective study. Retinal neurovascular structures in the macular and optic disc regions were examined in using OCT and OCTA.

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Acute mesenteric ischemia (AMI) is a potentially fatal abdominal emergency. The estimation of the severity of AMI is of great importance since changes in disease severity may have different impacts on the treatment options. This study aims to define laboratory and radiological parameters that can successfully predict the severity of AMI.

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Total extraperitoneal (TEP) approach is one of the commonly used minimally invasive method in inguinal hernia repair. There are limited data that compares the results of the telescopic dissection and balloon trocar for preperitoneal dissection. In our study, we aimed to retrospectively evaluate the TEP cases performed at our center and compare the results of these two techniques.

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Article Synopsis
  • In Turkey, a single-dose varicella vaccine was introduced in February 2013, aiming to reduce hospitalizations related to chickenpox among children under 18 years old.
  • A study analyzed hospitalization data from 2008 to 2018, comparing rates before and after the vaccine's introduction, finding a significant decrease in hospitalizations (3.79 to 2.87 per 100,000 children per year).
  • The most notable reduction was in children aged 1-5 years, with a 60.2% drop in hospitalizations post-vaccine, demonstrating the vaccine's effectiveness in preventing severe cases of varicella.
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Introduction: Chronic kidney disease (CKD) poses a significant global health burden, with increasing prevalence and high morbidity and mortality rates, particularly in end-stage kidney disease (ESKD). While traditional risk factors contribute, the exact mechanisms remain elusive, with inflammation playing a pivotal role. Medium cutoff (MCO) membranes offer promise in improving dialysis outcomes by efficiently clearing uremic toxins without substantial albumin loss.

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Profiles of primary brain abscesses and their impact on survival: An international ID-IRI study.

Int J Infect Dis

October 2024

Gulhane School of Medicine, Department of Infectious Diseases and Clinical Microbiology, University of Health Sciences, Ankara, Türkiye.

Article Synopsis
  • This study analyzed 331 patients with primary brain abscesses (PBAs) from 39 centers in 16 countries, focusing on infection causes, risk factors, and mortality outcomes over a 12-year period.
  • Study results showed that the majority of patients were middle-aged men (average age 46.8), with symptoms like headaches and fever; Gram-positive cocci were the most common pathogens.
  • Key factors influencing mortality at 42 days included intravenous drug use and malignancy, while factors affecting 180-day mortality included temporal lobe involvement and the presence of unidentified bacteria.
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Article Synopsis
  • - The study investigates how Human assumed central sensitization (HACS) affects the outcomes of transforaminal epidural steroid injections (TFESI) for patients with musculoskeletal disorders.
  • - Out of 65 patients, 31 had HACS, and while all patients showed improvement in pain and disability scores over time, those without HACS had significantly better outcomes.
  • - The findings suggest that HACS negatively impacts pain levels, disability, and mental health in patients receiving TFESI, indicating that treating HACS may be important for better recovery.
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Gender and Age Trends in HIV Incidence in Turkey between 1990 and 2021: Joinpoint and Age-Period-Cohort Analyses.

Medicina (Kaunas)

August 2024

Epidemiology PhD Program, Graduate School of Health Sciences, İstanbul Medipol University, 34810 İstanbul, Türkiye.

Despite a global decrease in HIV incidence, recent trends in Türkiye indicate a concerning rise, particularly among younger populations and women. This study investigates the local and regional dynamics influencing these trends using advanced epidemiological methodologies. Utilizing Age-period-cohort analysis and joinpoint regression, we analysed HIV incidence and prevalence data from the Global Burden of Disease study for Türkiye.

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Investigating the relationship between chronic pruritus and fibromyalgia: an evaluation of 200 patients.

Arch Dermatol Res

August 2024

Department of Physical Medicine and Rehabilitation Clinic, Ankara Training and Research Hospital, Health Sciences University, Ankara, Turkey.

Pruritus is a common complaint in dermatology outpatient clinics. It is defined as chronic pruritus if the symptoms last 6 weeks or longer. Fibromyalgia is a chronic, extensive pain syndrome that is well-known for its clinical signs, such as exhaustion, sleeping disorders, and some other pain symptoms.

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Background: Colonoscopy difficulty and procedure time can vary between cases, posing challenges for daily scheduling in endoscopy units. In the literature, cecal intubation time (CIT) is commonly used to assess colonoscopy difficulty, yet there is debate regarding the factors influencing CIT. This prospective observational study aimed to evaluate the factors influencing CIT.

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Background: Chatbots hold great potential to serve as support tool in diagnosis and clinical decision process. In this study, we aimed to evaluate the accuracy of chatbots in diagnosing pulmonary embolism (PE). Furthermore, we assessed their performance in determining the PE severity.

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Article Synopsis
  • This study investigates out-of-hospital cardiac arrest (OHCA) data in Türkiye, focusing on prognostic outcomes and influencing factors for patients aged 18 and older who were treated at 28 medical centers.
  • It found a survival rate upon hospital discharge of only 4.4%, with a significant majority of patients not receiving bystander CPR, which was only performed in 2.9% of cases.
  • Key predictors for better outcomes included male gender, initial shockable heart rhythms, shorter prehospital CPR duration, and no need for CPR in the emergency department, highlighting the importance of timely and effective CPR in emergencies.
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Background: Mycosis fungoides (MF) is the most common cutaneous lymphoma with a chronic disease course. MF patients may also suffer from systemic comorbidities such as cardiovascular and metabolic diseases.

Methods: In this study, we aimed to evaluate the demographic and clinical features of MF patients registered in the MF-TR registry system and to examine the relationship of these features with systemic comorbidities.

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The Predictive Utility of Circulating PCSK9 Levels on Diabetic Retinopathy Stage.

Curr Eye Res

October 2024

Department of Ophthalmology, Sultan Abdülhamid Han Training and Research Hospital, University of Health Science, Istanbul, Turkey.

Purpose: To investigate the value of proprotein-converting subtilisin kexin type 9 (PCSK9) levels in type 2 diabetes mellitus (T2D) patients with different stages of diabetic retinopathy (DR) and to compare these findings with a healthy control group without diabetes mellitus (DM).

Methods: A total of 135 patients, 100 of whom were patients with T2D and 35 of whom were in the health control group, were included in this prospective study. T2D patients were divided into three groups: the first group included 34 people with T2D without DR, the second group had 32 people with non-proliferative DR (NPDR), and the third group had 34 people with proliferative DR (PDR).

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Purpose: It is not clear whether cognitive functions are impaired in young patients with acute coronary syndrome (ACS). This study aims to detect whether or not there is cognitive impairment and cerebral changes in young patients with ACS undergoing percutaneous coronary intervention (PCI).

Patients And Methods: All 50 patients with ACS who were treated with primary PCI were eligible for this prospective study.

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Objectives: Chronic obstructive pulmonary disease (COPD) is a complex inflammatory condition that primarily impairs respiration but can also affect hemostasis. This study aimed to determine differences in platelet-related parameters and eosinophil between COPD patients and healthy controls.

Methods: We included 149 patients with stable COPD and 30 healthy controls who were recruited from the outpatient department of Chest Diseases.

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Objectives: Smoking is the major determinant of developing chronic obstructive pulmonary disease (COPD). A substantial proportion of patients with COPD continue smoking although they have significant respiratory symptoms, exacerbation history and comorbidities. We aimed to find the associated factors and clinical features of the patients who maintain smoking.

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Choroidal Thickness in Mild Autonomous Cortisol Secretion.

Sisli Etfal Hastan Tip Bul

June 2024

Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.

Objectives: To evaluate the patients with mild autonomous cortisol secretion (MACS) by means of choroidal thickness (CT) and also investigate whether CT may be a diagnostic tool in the management of MACS or not.

Methods: Twenty-seven patients with MACS and 25 age-sex-matched healthy controls were enrolled in this cross-sectional comparative study. All the participants underwent CT measurement by using Spectralis optical coherence tomography (Heidelberg Engineering, Heidelberg, Germany) with enhanced deep imaging mode at the subfoveal, 500-1000-1500 µm nasal and 500-1000-1500 µm temporal to the foveola.

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To evaluate the efficacy of SWEEPS mode of the Er: YAG laser(SL) and passive ultrasonic irrigation(PUI) in the eradication of microorganisms and in the inflammation detection by IL-1β. Thirty patients with chronic apical periodontitis(AP) were allocated into two groups: Group SL-SWEEPS laser activated irrigation(n = 15) and Group PUI-passive ultrasonic irrigation(n = 15). Bacteriological samples were taken before(S1) and after chemomechanical preparation(S2), and then after final irrigation activation(S3).

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Background: Electrodiagnostic testing (EDX) is important in the diagnosis and follow-up of neuropathic and myopathic diseases. This study aimed to demonstrate the compatibility between clinical prediagnosis and electrophysiological findings.

Methods: EDX results from 2004 to 2020 at the physical medicine and rehabilitation (PM&R) clinic were screened.

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