8 results match your criteria: "Sint-Lucas Hospital Ghent[Affiliation]"

Article Synopsis
  • Accurate measurement of the BCR::ABL1 fusion gene is crucial for managing chronic myeloid leukemia (CML), most commonly found as the p210 variant due to certain mRNA junctions.
  • The study analyzed 25 CML samples using two accredited centers with qPCR methods and compared results using advanced techniques like ddPCR, revealing significant differences in measurement accuracy.
  • Findings highlight that quantification differences may vary by center, impacting patient follow-up, and suggest that using specific standard curves or absolute quantification methods can mitigate these discrepancies.
View Article and Find Full Text PDF

Ductal carcinoma in situ (DCIS) of the breast is able to induce stromal changes, which likely reflect the crosstalk between DCIS and its microenvironment. These changes harbor prognostic information, although the interobserver variability of scoring stromal changes is moderate. A more robust evaluation of the DCIS-associated stroma is therefore needed.

View Article and Find Full Text PDF

Glomus tumors are benign tumors typically located in the subcutis or deep dermis of the subungual region of the fingers. Histologically, glomus tumors are divided into three subtypes, in descending order of frequency: solid glomus tumor, glomangioma and glomangiomyoma. We report a case of a symptomatic intracapsular juxtasynovial glomangiomyoma of the knee.

View Article and Find Full Text PDF

Emergency physicians have shown difficulties to combine their private and professional life. In addition to a very stressful environment, they have to deal with multiple sources of uncertainty. These factors may lead to psychological distress.

View Article and Find Full Text PDF

Objective And Importance: Listeria monocytogenes is a rare foodborne pathogen, causing both outbreaks and sporadic infections. Severe, systemic infections are more prevalent in at-risk populations, such as pregnant women, but occur mostly in older people and immunocompromised individuals. In this case report, we describe the presentation, diagnosis, and treatment of Listeria monocytogenes sepsis in an older patient, and we briefly review the literature about listeriosis and the importance of safe food practices.

View Article and Find Full Text PDF

Sarcoidosis is a multisystem granulomatous disease of unknown aetiology characterized by the presence of noncaseating granulomas. It may affect any organ including the kidney. A disordered calcium metabolism is most often responsible for the development of renal failure.

View Article and Find Full Text PDF