316 results match your criteria: "Singapore institute of Manufacturing Technology[Affiliation]"

1D moisture-enabled electric generators (MEGs) hold great promise for powering electronic textiles, but their current limitations in power output and operational duration restrict their application in wearable technology. This study introduces a high-performance yarn-based moisture-enabled electric generator (YMEG), which comprises a carbon-fiber core, a cotton yarn active layer with a radial gradient of poly(4-styrensulfonic acid) and poly(vinyl alcohol) (PSSA/PVA), and an aluminum wire as the outer electrode. The unique design maintains a persistent moisture gradient between the interior and exterior electrodes, enhancing performance through the continuous proton diffusion from PSSA and Al⁺ ions from the aluminum wire.

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Thermal cracking is one of the serious issues that deteriorates the processibility of laser powder bed fusion (LPBF) high-strength aluminum components. To date, the effects of processing parameters on crack formation are still not well understood. The purpose of this study is to understand the correlation between the thermal cycle and the hot cracking during LPBF of Al-Cu-Mg-Mn alloys.

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A Novel Crosslinking Approach for Biomanufacturing of a Collagen-Based Skin Dermal Template.

Macromol Biosci

December 2024

Biomanufacturing Technology, Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), Singapore, 138669, Singapore.

Third-degree burns result in extensive damage to the skin's epidermal and dermal layers, with limited treatment options available. Currently, xenogeneic collagen-based skin grafts are used as scaffolds to integrate into the wound bed and provide a template for neodermis formation. Existing commercial products like Integra dermal templates rely on a time-consuming and variable dehydrothermal (DHT) crosslinking process.

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Constructing High-Performance Yarn-Shaped Electrodes via Twisting-after-Coating Technique for Weavable Seawater Battery.

ACS Appl Mater Interfaces

December 2024

School of Materials and Energy, Southwest University, 1 Tiansheng Road, Chongqing 400715, P. R. China.

Seawater batteries (SWBs) are green aqueous power sources with great potential in marine applications. So far, SWBs are mainly built on rigid substrates, which hinders their adaptability to marine textile applications. Herein, we constructed a rechargeable yarn-shaped SWB consisting of nickel hexacyanoferrate (Ni-HCF)-modified carbon yarn (positive electrode), glass fiber diaphragm, and polyimide (PI)-modified carbon yarn (negative electrode).

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3D Printed Carbon Nanotube/Phenolic Composites for Thermal Dissipation and Electromagnetic Interference Shielding.

ACS Appl Mater Interfaces

December 2024

Artie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, Texas 77843, United States.

Here we demonstrate direct ink write (DIW) additive manufacturing of carbon nanotube (CNT)/phenolic composites with heat dissipation and excellent electromagnetic interference (EMI) shielding capabilities without curing-induced deformation. Such polymer composites are valuable for protecting electronic devices from overheating and electromagnetic interference. CNTs were used as a multifunctional nanofiller to improve electrical and thermal conductivity, printability, stability during curing, and EMI shielding performance of CNT/phenolic composites.

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Separable Hamiltonian neural networks.

Phys Rev E

October 2024

School of Computing, National University of Singapore, 13 Computing Drive, Singapore 117417 and CNRS International Research Laboratory 2955 on Artificial Intelligence, Singapore 138632.

Hamiltonian neural networks (HNNs) are state-of-the-art models that regress the vector field of a dynamical system under the learning bias of Hamilton's equations. A recent observation is that embedding a bias regarding the additive separability of the Hamiltonian reduces the regression complexity and improves regression performance. We propose separable HNNs that embed additive separability within HNNs using observational, learning, and inductive biases.

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Untethered bistable origami crawler for confined applications.

Commun Eng

October 2024

Department of Biomedical Engineering, National University of Singapore, Singapore, 117575, Singapore.

Magnetically actuated miniature origami crawlers are capable of robust locomotion in confined environments but are limited to passive functionalities. Here, we propose a bistable origami crawler that can shape-morph to access two separate regimes of folding degrees of freedom that are separated by an energy barrier. Using the modified bistable V-fold origami crease pattern as the fundamental unit of the crawler, we incorporated internal permanent magnets to enable untethered shape-morphing.

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A facile microfluidic chip design for DNA detection using dengue serotypes as a proof-of-concept case study.

Biotechnol Notes

November 2023

Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-04, Singapore, 138634, Republic of Singapore.

Dengue fever is caused by any of the four serotypes of dengue viruses, DENV-1, DENV-2, DENV-3 and DENV-4 spread by mosquito bites and is important to distinguish between them due to lack of cross-protective neutralizing antibodies for each serotype. Secondary infections also put individuals at higher risk for severe dengue illness than those who have not been previously infected. Current preferred assays include reverse transcription-PCR (RT-PCR) and ELISA.

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Wearable Sensors, Data Processing, and Artificial Intelligence in Pregnancy Monitoring: A Review.

Sensors (Basel)

October 2024

Singapore Institute of Manufacturing Technology, Agency for Science, Technology and Research (A*STAR), 5 Cleantech Loop, Singapore 636732, Singapore.

Article Synopsis
  • Pregnancy monitoring is crucial for the health of mothers and fetuses, with WHO reporting 287,000 maternal deaths in 2020, sparking a need for more accessible options than traditional hospital visits.
  • Advances in wearable sensors and AI are making home-based, non-invasive health monitoring for pregnant women more feasible and convenient.
  • The review highlights the role of wearable sensors in tracking physiological signals and how AI can enhance early detection and diagnosis, while also addressing ongoing challenges like accuracy and data privacy.
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Achieving biomimetic porosity and strength of bone in magnesium scaffolds through binder jet additive manufacturing.

Biomater Adv

January 2025

Additive Manufacturing Division, Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research (A*STAR), 5 Cleantech Loop, 636732 Singapore, Singapore. Electronic address:

Magnesium (Mg) alloys are a promising candidate for synthetic bone tissue substitutes. In bone tissue engineering, achieving a balance between pore characteristics that facilitate biological functions and the essential stiffness required for load-bearing functions is extremely challenging. This study employs binder jet additive manufacturing to fabricate an interconnected porous structure in Mg alloys that mimics the microporosity and mechanical properties of human cortical bone types.

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Effects of Tempering on Microstructure and Properties of Additive Manufacturing Cu-Bearing AISI 431 Steel.

Materials (Basel)

September 2024

Key Laboratory of Hunan Province of Equipment Safety Service Technology under Extreme Environment, Hengyang 421001, China.

Article Synopsis
  • - The study focuses on AISI 431 martensitic stainless steels infused with 2.5 wt% copper, which were created using laser-directed energy deposition and a single-step tempering process at 600 °C.
  • - Results showed that the microstructure evolved with increased tempering time, leading to the formation of copper-enriched nano-precipitates and improved mechanical properties such as microhardness and strength, particularly at one hour of tempering.
  • - The 431-2.5Cu MSS outperformed traditional 431 MSS by achieving high ultimate tensile and yield strength (1611 MPa and 1334 MPa respectively) and significant elongation (16.3%) with a simpler tempering process
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Recent advancements in soft robotics have been emerging as an exciting paradigm in engineering due to their inherent compliance, safe human interaction, and ease of adaptation with wearable electronics. Soft robotic devices have the potential to provide innovative solutions and expand the horizons of possibilities for biomedical applications by bringing robots closer to natural creatures. In this review, we survey several promising soft robot technologies, including flexible fluidic actuators, shape memory alloys, cable-driven mechanisms, magnetically driven mechanisms, and soft sensors.

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A Modeling Framework for the Thermoforming of Carbon Fiber Reinforced Thermoplastic Composites.

Polymers (Basel)

July 2024

Institute of High Performance Computing (IHPC), Agency for Science, Technology and Research (A*STAR), 1 Fusionopolis Way, #16-16, Connexis North Tower, Singapore 138632, Singapore.

A comprehensive modeling framework for the thermoforming of polymer matrix woven laminate composite was developed. Two numerical indicators, the slip path length and traction magnitude, have been identified to be positively correlated to matrix smearing and wrinkling defects. The material model has been calibrated with picture-frame experimental results, and the prediction accuracy for intra-ply shear and thickness distribution was examined with measurements of the physically formed parts.

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Transient Amplification of Broken Symmetry in Elastic Snap-Through.

Phys Rev Lett

June 2024

Mathematical Institute, University of Oxford, Woodstock Rd, Oxford OX2 6GG, United Kingdom.

A snap-through bifurcation occurs when a bistable structure loses one of its stable states and moves rapidly to the remaining state. For example, a buckled arch with symmetrically clamped ends can snap between an inverted and a natural state as the ends are released. A standard linear stability analysis suggests that the arch becomes unstable to asymmetric perturbations.

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Expandable-RCNN: toward high-efficiency incremental few-shot object detection.

Front Artif Intell

April 2024

Department of Electrical and Computer Engineering, National University of Singapore, Singapore, Singapore.

This study aims at addressing the challenging incremental few-shot object detection (iFSOD) problem toward online adaptive detection. iFSOD targets to learn novel categories in a sequential manner, and eventually, the detection is performed on all learned categories. Moreover, only a few training samples are available for all sequential novel classes in these situations.

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Enhanced Plastic Stability: Achieving High Performance in a Al6xxx Alloy Fabricated by Additive Manufacturing.

Adv Mater

August 2024

Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research (A*STAR), 5 Cleantech Loop, #01-01 CleanTech Two Block B, Singapore, 636732, Republic of Singapore.

Additive manufacturing (AM) facilitates the creation of materials with unique microstructural features and distinctive phenomena as compared to conventional manufacturing methods. Among the various well-fabricated AM alloys, aluminum alloys garner substantial attention due to their extensive applications in the automotive and aerospace industries. In this work, an Al6xxx alloy is successfully fabricated with outstanding performance.

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In recent years, there has been widespread adoption of machine learning (ML) technologies to unravel intricate relationships among diverse parameters in various additive manufacturing (AM) techniques. These ML models excel at recognizing complex patterns from extensive, well-curated datasets, thereby unveiling latent knowledge crucial for informed decision-making during the AM process. The collaborative synergy between ML and AM holds the potential to revolutionize the design and production of AM-printed parts.

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Cell-free RNAs and extracellular vesicles (EVs) are valuable biomarkers in liquid biopsies, but they are prone to preanalytical variabilities such as nonstandardized centrifugation or blood degradation. Herein, we report a high-throughput and label-free inertial microfluidic device (ExoArc) for isolation of platelet-free plasma from blood for RNA and EV analysis. Unlike conventional inertial microfluidic devices widely used for cell sorting, a submicrometer size cutoff (500 nm) was achieved which completely removed all leukocytes, RBCs, platelets, and cellular debris based on differential lateral migration induced by Dean vortices.

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Smart salt-responsive thread for highly sensitive microfluidic glucose detection in sweat.

Lab Chip

February 2024

Key Laboratory of Luminescence Analysis and Molecular Sensing, Ministry of Education, School of Materials & Energy, Southwest University, Chongqing 400715, P. R. China.

Thread-based microfluidic colorimetric sensors have been deemed a potential tool that may be incorporated into textiles for non-invasive sweat analysis. Nevertheless, their poor performance significantly limits their practical uses in sweat glucose detection down to 20 μM. Herein, a microfluidic glucose sensing device containing a salt-responsive thread is developed for the highly sensitive detection of glucose in human sweat.

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Methicillin-resistant Staphylococcus aureus (MRSA) causes a wide range of hospital and community-acquired infections worldwide. MRSA is associated with worse clinical outcomes that can lead to multiple organ failure, septic shock, and death, making timely diagnosis of MRSA infections very crucial. In the present work, we develop a method that enables the positive enrichment of bacteria from spiked whole blood using protein coated magnetic beads, followed by their lysis, and detection by a real-time multiplex PCR directly.

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Commercialization of skin substitutes for third-degree burn wounds.

Trends Biotechnol

April 2024

Biomanufacturing Technology, Bioprocessing Technology Institute (BTI), Agency for Science, Technology, and Research (A*STAR), 20 Biopolis Way, Singapore 138668, Singapore. Electronic address:

Technological advances have increasingly provided more and better treatment options for patients with severe burns. Here, we provide a bird's-eye view of the product development process for third-degree burn wounds with considerations of the critical interaction with regulatory bodies, existing technological gaps, and future directions for skin substitutes.

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In metallurgy, mechanical deformation is essential to engineer the microstructure of metals and to tailor their mechanical properties. However, this practice is inapplicable to near-net-shape metal parts produced by additive manufacturing (AM), since it would irremediably compromise their carefully designed geometries. In this work, we show how to circumvent this limitation by controlling the dislocation density and thermal stability of a steel alloy produced by laser powder bed fusion (LPBF) technology.

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Advances in Folic Acid Biosensors and Their Significance in Maternal, Perinatal, and Paediatric Preventive Medicine.

Biosensors (Basel)

September 2023

Singapore Institute of Manufacturing Technology (SIMTech), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-04, Singapore 138634, Singapore.

Auxotrophic primates like human beings rely on exogenous dietary vitamin B supplementation to meet their metabolic demands. Folates play a crucial role in nucleotide synthesis and DNA methylation. Maternal folate deficiency causes several pregnancy-related complications, perinatal defects, and early childhood cognitive impairments.

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Unmanned aerial vehicle-aided visible light communication (UAV-VLC) can be used to realize joint emergency illumination and communication, but the endurance of UAV is a key limiting factor. In order to overcome this limitation, this paper proposes the use of an angle diversity transmitter (ADT) to enhance the energy efficiency of the UAV-VLC system. The ADT is designed with one bottom LED and several evenly distributed inclined side LEDs.

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Gingiva plays a crucial barrier role at the interface of teeth, tooth-supporting structures, microbiome, and external agents. To mimic this complex microenvironment, an in vitro microphysiological platform and biofabricated full-thickness gingival equivalents (gingiva-on-chip) within a vertically stacked microfluidic device is developed. This design allowed long-term and air-liquid interface culture, and host-material interactions under flow conditions.

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