1 results match your criteria: "Singapore School of Biological Sciences Nanyang Technological University[Affiliation]"
MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling.
EMBO J
June 2014
Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore City, Singapore Department of Biological Sciences, National University of Singapore, Singapore City, Singapore School of Biological Sciences Nanyang Technological University, Singapore City, Singapore
Several transcription factors (TFs) have been implicated in neuroectoderm (NE) development, and recently, the TF PAX6 was shown to be critical for human NE specification. However, microRNA networks regulating human NE development have been poorly documented. We hypothesized that microRNAs activated by PAX6 should promote NE development.
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