6 results match your criteria: "Singapore Bioprocessing Technology Institute[Affiliation]"

Blau syndrome (BS) is a very rare autosomal dominant juvenile inflammatory disorder caused by mutation in nucleotide-binding oligomerization domain containing 2 . Usually, dermatitis is the first symptom that appears in the 1 year of life. About 220 BS cases with confirmed mutation have been reported.

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H syndrome - the first report in Malaysia.

Int J Dermatol

October 2019

Paediatric Dermatology Unit, Paediatric Institute, Hospital Kuala Lumpur, Ministry of Health, Kuala Lumpur, Malaysia.

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Cell type dependent morphological adaptation in polyelectrolyte hydrogels governs chondrogenic fate.

Biomed Mater

April 2016

Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, NUHS Tower Block, Level 11, 1E Kent Ridge Road, 119288, Singapore. Bioprocessing Technology Institute, 20 Biopolis Way, The Centros, 138669, Singapore.

Article Synopsis
  • The study investigates how different cell types (mesenchymal stem cells and chondrocytes) respond to various 3D environments for cartilage repair, focusing on the impact of aligned collagen type I in hydrogels.
  • Chondrocytes in a collagen-free matrix maintained a hyaline phenotype in clusters, while MSCs differentiated into a fibro-superficial zone-like type, emphasizing the importance of cell morphology in cartilage tissue engineering.
  • The research highlights that designing biodegradable matrices that cater to the specific needs of different cell types is crucial for effectively regenerating healthy articular cartilage.
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Metabolic and transcriptional regulatory mechanisms underlying the anoxic adaptation of rice coleoptile.

AoB Plants

June 2014

Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore Bioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, #06-01, Centros, Singapore 138668, Singapore

The ability of rice to germinate under anoxia by extending the coleoptile is a highly unusual characteristic and a key feature underpinning the ability of rice seeds to establish in such a stressful environment. The process has been a focal point for research for many years. However, the molecular mechanisms underlying the anoxic growth of the coleoptile still remain largely unknown.

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