1 results match your criteria: "Singapore 119074 Genome Institute of Singapore[Affiliation]"
A set of powerful negative selection systems for unmodified Enterobacteriaceae.
Nucleic Acids Res
July 2015
National University of Singapore, Department of Medicine, Yong Loo Lin School of Medicine, 1E Kent Ridge Road, NUHS Tower Block, Level 10, Singapore 119074 Genome Institute of Singapore, Infectious Diseases Group, 60 Biopolis Street, Genome, #02-01, Singapore 138672
Article Synopsis
- This study presents a new genetic mutation strategy using toxins that works well with clinical strains of E. coli and Salmonella without needing specific adjustments for each strain.
- The system offers better selection strength compared to previous methods, making it easier to conduct genetic experiments in various bacteria.
- It allows for allele transfers between E. coli strains without phage and can be adapted for use in other types of bacteria, addressing the limitations of current genetic tools.