159,831 results match your criteria: "Singapore; and Duke-NUS Medical School[Affiliation]"
ACS Appl Mater Interfaces
December 2024
State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology, School of Microelectronics, Xidian University, Xi'an 710071, P. R. China.
Flexibility enhancement is a pressing issue in the current development of advanced lithium-metal battery applications. Many types of organic polymers are inherently flexible, which can form a composite structure enhancing electrode flexibility. However, organic polymers have a negative influence on the plating and stripping of lithium-metal anodes, and the large number of polymers block the pore of the material, reducing the utilization of the active site.
View Article and Find Full Text PDFAliment Pharmacol Ther
December 2024
Division of Gastroenterology, MASLD Research Center, University of California at San Diego, San Diego, California, USA.
Int J Ment Health Addict
December 2024
Department of Psychology, University of Waterloo, Waterloo, ON, Canada.
This study examined differences in quit attempts, 1-month quit success, and vaping status at follow-up among a cohort of 3709 daily smokers with and without depression, anxiety, and regular alcohol use who participated in both the 2018 and 2020 International Tobacco Control Four Country Smoking and Vaping (ITC 4CV) Surveys. At baseline, a survey with validated screening tools was used to classify respondents as having no, or one or more of the following: 1) depression, 2) anxiety, and 3) regular alcohol use. Multivariable adjusted regression analyses were used to examine whether baseline (2018) self-report conditions were associated with quit attempts; quit success; and vaping status by follow-up (2020).
View Article and Find Full Text PDFNetw Neurosci
December 2024
Retired Professor, The University of Melbourne, Victoria, Australia.
Several recent studies have optimized deep neural networks to learn high-dimensional relationships linking structural and functional connectivity across the human connectome. However, the extent to which these models recapitulate individual-specific characteristics of resting-state functional brain networks remains unclear. A core concern relates to whether current individual predictions outperform simple benchmarks such as group averages and null conditions.
View Article and Find Full Text PDFACS Cent Sci
December 2024
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, P. R. China.
An efficient regiospecific co-assembly (RSCA) strategy is developed for general synthesis of mesoporous metal oxides with pore walls precisely decorated by highly dispersed noble metal nanocrystals with customized parameters (diameter and composition). It features the rational utilization of the specific interactions between hydrophilic molecular precursors, hydrophobic noble metal nanocrystals, and amphiphilic block copolymers, to achieve regiospecific co-assembly as confirmed by molecular dynamics simulations. Through this RSCA strategy, we achieved a controllable synthesis of a variety of functional mesoporous metal oxide composites (e.
View Article and Find Full Text PDFHealth Care Sci
December 2024
Centre for Quantitative Medicine, Duke-NUS Medical School Singapore.
Background: Pneumothorax is a medical emergency caused by the abnormal accumulation of air in the pleural space-the potential space between the lungs and chest wall. On 2D chest radiographs, pneumothorax occurs within the thoracic cavity and outside of the mediastinum, and we refer to this area as "lung + space." While deep learning (DL) has increasingly been utilized to segment pneumothorax lesions in chest radiographs, many existing DL models employ an end-to-end approach.
View Article and Find Full Text PDFProstate Int
December 2024
Department of Urology, National University Hospital, National University Health System, Singapore.
Background: Prostate cancer is now one of the most prevalent cancers in men in Asia. As the average life expectancy of Asian males with prostate cancer increases with the availability of treatment options, the possible risk of cardiac-related adverse effects arising from androgen-receptor-targeted agents (ARTAs) may be increased due to the greater exposure. We aim to perform a meta-analysis on the incidence of cardiac-related adverse events in Asian patients with prostate cancer treated with ARTAs.
View Article and Find Full Text PDFAquac Nutr
December 2024
Tropical Future Institute, James Cook University, Singapore, Singapore.
Malabar snapper () is an economically important marine fish throughout the Indo-Pacific, with an emerging aquaculture industry. Although generic marine feeds are available for production, these are not optimised for this species. Understanding energy utilisation and balance can provide insight into suitable macronutrient profiles for new species to provide a baseline for future development.
View Article and Find Full Text PDF3D Print Addit Manuf
December 2024
School of Optical and Electronic Information, Huazhong University of Science and Technology, Wuhan, P.R. China.
Thermal cracking is one of the serious issues that deteriorates the processibility of laser powder bed fusion (LPBF) high-strength aluminum components. To date, the effects of processing parameters on crack formation are still not well understood. The purpose of this study is to understand the correlation between the thermal cycle and the hot cracking during LPBF of Al-Cu-Mg-Mn alloys.
View Article and Find Full Text PDF3D Print Addit Manuf
December 2024
School of Mechanical Engineering, Pusan National University, Busan, Korea.
Heat accumulation due to repetitive simple laser processing paths during building up a three-dimensional structure is a well-known issue that needs to be settled to reduce the excessively high residual stress and thermal deformation in a powder bed fusion (PBF) additive manufacturing process. Because of the dependency of laser path on the thermal dispersion, it is essential to analyze the heat accumulation phenomenon during laser processing. A computational fluid dynamics (CFD) analysis based on the volume of fraction method is used to optimize the laser path for minimizing the local heating up in the PBF process.
View Article and Find Full Text PDFJ Geriatr Cardiol
November 2024
Department of Laboratory Medicine, Affiliated Sixth People's Hospital South Campus, Shanghai Jiaotong University, Shanghai, China.
Objectives: Autologous blood outgrowth endothelial cells (BOECs) have been proposed to induce therapeutic angiogenesis for treating cardiovascular diseases (CVDs). The aim of the present study was to investigate the proliferative potential and angiogenic characteristics of BOECs among middle-aged and older adults, the population particularly susceptible to CVDs.
Methods: BOECs were isolated from 48 peripheral blood samples of subjects aged 56 ± 4 years.
Interdiscip Nurs Res
December 2024
Alice Lee Centre for Nursing Studies and Cardiovascular-Metabolic Diseases Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Chemosphere
December 2024
Department of Environmental Medicine and Climate Science, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1057, New York, NY, 10029, USA. Electronic address:
Background: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social deficits and repetitive behaviors. Environmental pollutants may contribute to the etiology of ASD, but studies of perfluoroalkyl substances (PFAS) have shown conflicting results.
Objectives: We assessed associations between cord blood concentrations of PFAS with autistic traits at age seven years in a Singaporean birth cohort.
Ophthalmol Retina
December 2024
F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Neural Netw
December 2024
College of Science, Shantou University, Shantou 515063, China. Electronic address:
The explainability of Graph Neural Networks (GNNs) is critical to various GNN applications, yet it remains a significant challenge. A convincing explanation should be both necessary and sufficient simultaneously. However, existing GNN explaining approaches focus on only one of the two aspects, necessity or sufficiency, or a heuristic trade-off between the two.
View Article and Find Full Text PDFClin Imaging
December 2024
Department of Diagnostic Radiology, Singapore General Hospital, Singapore; Department of Diagnostic Radiology, Khoo Teck Puat Hospital, Singapore.
J Colloid Interface Sci
December 2024
School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300400 PR China. Electronic address:
The formation and growth of lithium dendrites is an ever-present and urgent problem in lithium-ion batteries (LIBs). At the same time, the low melting point of commercial polyolefin separators may lead to safety issues during application. On this basis, in this work, poly (m-phenylene isophthalamide) (PMIA)/Zr-based metal-organic framework (NH-UiO-66) composite separator was prepared by non-solvent induced phase separation (NIPS).
View Article and Find Full Text PDFCurr Opin Genet Dev
December 2024
Institute of Molecular and Cell Biology (IMCB), and National University of Singapore (NUS), Singapore. Electronic address:
Ther Innov Regul Sci
December 2024
GSK, 20 Avenue Fleming, Wavre, 1300, Belgium.
Sci Rep
December 2024
School of Civil Engineering, Southeast University, Nanjing, 211189, China.
Collapsible loess soils, known for their significant volume reduction upon the wetting, pose critical challenges in the geotechnical engineering. The estimation of the wetting-induced settlement is crucial for the foundation design and the determination of the negative skin friction on the pile. In this paper, a new method is proposed to estimate the wetting induced collapse from the wetting soil-water characteristic curve (SWCC) and the index properties of the loess soils.
View Article and Find Full Text PDFSci Rep
December 2024
Earth Observatory of Singapore, Nanyang Technological University, Singapore, 639798, Singapore.
Coastal populations are susceptible to relative sea-level (RSL) rise and accurate local projections are necessary for coastal adaptation. Local RSL rise may deviate from global mean sea-level rise because of processes such as geoid change, glacial isostatic adjustment (GIA), and vertical land motion (VLM). Amongst all factors, the VLM is often inadequately estimated.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Biosciences, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Chennai, 602 105, India.
Chimp optimization algorithm (CHOA) is a recently developed nature-inspired technique that mimics the swarm intelligence of chimpanzee colonies. However, the original CHOA suffers from slow convergence and a tendency to reach local optima when dealing with multidimensional problems. To address these limitations, we propose TASR-CHOA, a twofold adaptive stochastic reinforced variant.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Women's Anesthesia, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore, 229899, Singapore.
Mothers encounter several challenges to sustain breastfeeding until the recommended 6 months of age. There is limited evidence on the impact of women's labor pain experiences upon cessation of breastfeeding. We aimed to investigate the association between women's labor pain experiences, intrapartum interventions, and pre-birth psychological vulnerabilities and cessation of breastfeeding.
View Article and Find Full Text PDFSci Rep
December 2024
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), 61 Biopolis Drive, Proteos, Singapore, 138673, Republic of Singapore.
Signaling interplay between the histamine 1 receptor (H1R) and transient receptor potential cation channel subfamily V member 1 (TRPV1) in mediating histaminergic itch has been well-established in mammalian models, but whether this is conserved in humans remains to be confirmed due to the difficulties in obtaining human sensory neurons (SNs) for experimentation. Additionally, previously reported species-specific differences in TRPV1 function indicate that use of human SNs is vital for drug candidate screening to have a higher chance of identifying clinically effective TRPV1 antagonists. In this study, we built a histamine-dependent itch model using peripheral SNs derived from human induced pluripotent stem cells (hiPSC-SNs), which provides an accessible source of human SNs for pre-clinical drug screening.
View Article and Find Full Text PDFOpen Heart
December 2024
Liverpool Centre for Cardiovascular Science, at University of Liverpool, Liverpool John Moores University and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom, Liverpool, UK