Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionllrptepm5rnahhtnbfj7617poptfucqg): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
124 results match your criteria: "Siddaganga Institute of Technology[Affiliation]"
Expert Rev Mol Diagn
December 2024
Department of Biotechnology, Siddaganga Institute of Technology, Tumakuru, India.
Introduction: The liquid biopsy is a breakthrough in the field of medical diagnostics. It serves as a sentinel that can quietly detect even the subtlest aberrations that indicate the presence of disease. They make it possible to uncover relevant genetic factors of tumors with minimal to no risk to cancer patients.
View Article and Find Full Text PDFPeerJ Comput Sci
November 2024
Computer Science & Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education (MAHE), Manipal, Karanataka, India.
Chronic kidney disease (CKD) involves numerous variables, but only a few significantly impact the classification task. The statistically equivalent signature (SES) method, inspired by constraint-based learning of Bayesian networks, is employed to identify essential features in CKD. Unlike conventional feature selection methods, which typically focus on a single set of features with the highest predictive potential, the SES method can identify multiple predictive feature subsets with similar performance.
View Article and Find Full Text PDFBiotechnol Notes
February 2024
Department of Biotechnology Engineering, Chandigarh University, Mohali, 140413, India.
The excessive discharge and accumulation of solid organic waste into the environment is of severe concern across the globe. Thus, an efficient waste management system is important to mitigate health risks to humans, minimize harmful impacts on the environment, and ensure a sustainable ecosystem. The organic waste is converted into value-added products either using microorganisms or heat energy; these methods are commonly known as biochemical and thermochemical techniques.
View Article and Find Full Text PDFJ Orthop
May 2025
Department of Civil Engineering, Government Engineering College Mosalehosahalli, 573212, India.
Lower Back Pain (LBP) is a global health issue, with increasing prevalence, partly attributed to vehicular vibrations experienced by motorcyclists. The L4 lumbar vertebra is responsible for greater mobility and flexibility of the body, but also is the most crucial body element affected by vehicular vibrations. Anthropometric properties, types of speed humps, and vehicle types are the critical variables that impact bone health during riding, need to be studied.
View Article and Find Full Text PDFComput Biol Med
January 2025
Central Research Laboratory, KS Hegde Medical Academy, Nitte (Deemed to be University), Mangalore, 575018, Karnataka, India; Center for Bioinformatics and Biostatistics, Nitte (Deemed to be University), Mangalore, 575018, Karnataka, India. Electronic address:
MTAN is an attainable therapeutic target for H. pylori because it may minimize virulence production, limit resistance, and impair quorum sensing without affecting gut flora. Here, 457 compounds with anti-H.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Center for Research and Innovation, Adichunchanagiri School of Natural Sciences, Adichunchanagiri University, B G Nagara 571448, India.
The current effort focuses on creating an effective adsorbent for Cr (VI) adsorption due to the growing need to address Cr (VI) pollution in aqueous solutions. Chitosan, a biopolymer and polysaccharide with several functional sites, is immobilized on alginate using the ion exchange technique. Both prior to and following Cr (VI) adsorption, the material's shape, crystallinity, and functional groups are reported.
View Article and Find Full Text PDFHeliyon
September 2024
School of Chemical Engineering, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
RSC Adv
October 2024
Department of Mechanical Engineering, P. A. College of Engineering, Visvesvaraya Technological University Belagavi Mangaluru India
This study explores the characteristics and potential engineering applications of Cu-Al-Mn and Cu-Al-Be-Mn shape memory alloys (SMAs). The research investigates the chemical composition, transformation temperatures, and mechanical properties of these SMAs when incorporated into Al metal matrix composites (MMCs). It was found that the addition of Mn and Be, has a significant impact on the performance of Cu-Al alloys.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
Department of Physics, Vijayanagara Sri Krishnadevaraya University, Ballari 583 105, India. Electronic address:
In this study, the absorption and fluorescence characteristics of sulfa drugs, specifically Sulfadiazine (SDZ), Sulfamerazine (SMZ), and Sulfamethazine (STZ), were examined across a pH range of 1-14. The absorption and fluorescence spectra of these sulfa drugs showed significant changes depending on the pH value. Analysis of their pH-dependent absorption and fluorescence properties indicated that these sulfa drugs could used to design molecular logic gates.
View Article and Find Full Text PDFAnn Pharm Fr
August 2024
Department of Biotechnology, Siddaganga Institute of Technology, 572102 Tumkur, Karnataka, India.
Objective: To develop and validate a rapid, accurate, economical, effective and greenery RP-HPLC method for the determination of Zolmitriptan in tablet dosage form.
Material And Method: RP-HPLC method was developed using Luna (C) (4.6×250mm, 5μm) column and Sodium phosphate buffer (pH 4.
Sensors (Basel)
August 2024
Department of Computer Science, University of Memphis, Memphis, TN 38152-3240, USA.
Task scheduling is a critical challenge in cloud computing systems, greatly impacting their performance. Task scheduling is a nondeterministic polynomial time hard (NP-Hard) problem that complicates the search for nearly optimal solutions. Five major uncertainty parameters, i.
View Article and Find Full Text PDFNanomaterials (Basel)
July 2024
Centre for Advanced Research and Development, CHRIST (Deemed to be University), Bengaluru 560029, Karnataka, India.
Poly(3,4-ethylenedioxythiophene) (PEDOT) and PEDOT-functionalized carbon nanoparticles (f-CNPs) were synthesized by in situ chemical oxidative polymerization and pyrolysis methods. f-CNP-PEDOT nanocomposites were prepared by varying the concentration of PEDOT from 1 to 20% by weight (i.e.
View Article and Find Full Text PDFJ Neurosci Methods
October 2024
Vel Tech Rangarajan Dr.Sagunthala R & D Instiute of Science and Technology, Chennai, India. Electronic address:
Background: Accurately diagnosing brain tumors from MRI scans is crucial for effective treatment planning. While traditional methods heavily rely on radiologist expertise, the integration of AI, particularly Convolutional Neural Networks (CNNs), has shown promise in improving accuracy. However, the lack of transparency in AI decision-making processes presents a challenge for clinical adoption.
View Article and Find Full Text PDFPLoS One
June 2024
Department of Studies in Botany, University of Mysore, Mysuru, Karnataka, India.
The present study was focused on exploring the efficient inhibitors of closed state (form) of type III effector Xanthomonas outer protein Q (XopQ) (PDB: 4P5F) from the 44 phytochemicals of Picrasma quassioides using cutting-edge computational analysis. Among them, Kumudine B showed excellent binding energy (-11.0 kcal/mol), followed by Picrasamide A, Quassidine I and Quassidine J with the targeted closed state of XopQ protein compared to the reference standard drug (Streptomycin).
View Article and Find Full Text PDFBiomed Res Int
June 2024
Sri Siddhartha Institute of Technology, Tumakuru, India.
Existing security issues like keys, pins, and passwords employed presently in almost all the fields that have certain limitations like passwords and pins can be easily forgotten; keys can be lost. To overcome such security issues, new biometric features have shown outstanding improvements in authentication systems as a result of significant developments in biological digital signal processing. Currently, the multimodal authentications have gained huge attention in biometric systems which can be either behavioural or physiological.
View Article and Find Full Text PDFFront Chem
May 2024
School of Physical Sciences, Amrita Vishwa Vidyapeetham, Mysuru, India.
an opportunistic human pathogenic bacterium, exhibits resistance to conventional antibiotics by exploiting its quorum sensing mechanism to regulate virulence factor expression. In light of this, disrupting the quorum sensing mechanism presents a promising avenue for treating infections caused by this pathogen. The study focused on using the cytoplasmic quorum sensing receptor CviR from as a model target to identify novel quorum sensing inhibitors from through computational approaches.
View Article and Find Full Text PDFNanotechnology
June 2024
Department of Physics, Govt. Arts and Science College, Meenchanda, Calicut (Affiliated to Calicut University), 673018 Kerala, India.
A low-temperature polymer-assisted wet chemical method was used to synthesise Cu-doped ZnO bicone nanoflowers at three different polyethylene glycol (PEG) concentrations. The effects of PEG concentration on the structural, morphological and optical properties of Cu doped ZnO nanostructures were studied. X-ray diffraction studies revealed that the as-synthesized Cu doped ZnO nanostructures are highly crystalline with a hexagonal wurtzite phase.
View Article and Find Full Text PDFACS Omega
March 2024
Institute of Chemistry, B.J. Campus, The Islamia University of Bahawalpur, Bahawalpur 36000, Pakistan.
infection is widespread in 50% of the world's population and is associated with gastric ulcers and related disorders that ultimately culminate in gastric cancer. Levofloxacin-based, or clarithromycin-based, triple therapy is frequently used to inhibit the bacterial urease enzyme for the eradication of . A comprehensive investigation based on the urease inhibitory profiles of antibiotics and their computational implications is lacking in the scientific literature.
View Article and Find Full Text PDFHeliyon
January 2024
Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
PLoS One
January 2024
School of Physical Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, Karnataka, India.
The present study explores the epidermal growth factor receptor (EGFR) tyrosine kinase inhibition efficacy of secondary metabolites in Trichoderma spp. through molecular docking, molecular dynamics (MD) simulation and MM-PBSA approach. The result of molecular docking confirmed that out of 200 metabolites screened, three metabolites such as Harzianelactone A, Pretrichodermamide G and Aspochalasin M, potentially bound with the active binding site of EGFR tyrosine kinase domain(PDB ID: 1M17) with a threshold docking score of ≤- 9.
View Article and Find Full Text PDFJ Fluoresc
January 2024
Department of Physics and Electronics, CHRIST University, Bengaluru, Central Campus, Bengaluru, 560029, Karnataka, India.
A series of unique four mono-azo substituted anthraquinone analogue were synthesized by using the anthraquinone components in the diazo-coupling technique. The FT-IR, H NMR, and HRMS, data were used to confirm the structure of the molecules, and spectroscopic techniques like UV-Vis, and photoluminescence spectroscopy were employed to estimate the photophysical properties of the molecules. The molecular optimized geometry and frontier molecular orbitals were estimated using density functional theory.
View Article and Find Full Text PDFNanoscale Adv
November 2023
Bio-INvENT Lab, Department of Chemical Engineering, Siddaganga Institute of Technology B. H. Road Tumakuru 572103 India +91 816 2214038.
Cold stress (hypothermia) during storage and cytokine stress due to acute allograft rejection adversely affect the donor corneal endothelium in the short term. Pharmacological pre-treatment (before transplantation) of the donor corneal endothelium or cells (propagated for cell injection therapy) with microtubule stabilizers, cold stress protectants, and other molecules is an attractive strategy to tackle damage caused by hypothermia and cytokine stress. These molecules can be delivered intracellularly to the donor corneal endothelium or cells at controlled rates for desired periods and with one-time administration using nanoparticles.
View Article and Find Full Text PDFMetabolites
November 2023
Department of Pharmacology, Raghavendra Institute of Pharmaceutical Education and Research, JNTUA, Anantapuramu 515721, Andhra Pradesh, India.
One of the primary therapeutic approaches for managing Alzheimer's disease (AD) involves the modulation of Acetylcholine esterase (AChE) activity to elevate acetylcholine (ACh) levels inside the brain. The current study employed computational chemistry approaches to evaluate the inhibitory effects of CTN on AChE. The docking results showed that Citronellal (CTN) and standard Donepezil (DON) have a binding affinity of -6.
View Article and Find Full Text PDFJ Neurochem
October 2023
Department of Clinical Psychopharmacology and Neurotoxicology, National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, Karnataka, India.
Traumatic brain injury (TBI) causes significant neurological deficits and long-term degenerative changes. Primary injury in TBI entails distinct neuroanatomical zones, i.e.
View Article and Find Full Text PDFBiophys Chem
October 2023
Department of Biotechnology, Siddaganga Institute of Technology, Tumakuru, Karnataka, India. Electronic address:
Cholesteryl Ester Transfer Protein (CETP) is a plasma glycoprotein that intervenes the reverse cholesterol transport (RCT) by equimolar exchange of Cholesteryl esters (CE) and Triglycerides (TGs) between anti-atherogenic High-Density Lipoproteins (HDLs) and pro-atherogenic Low-Density Lipoproteins (LDLs) resulting in the increased concentration of CEs in LDL. This is a potential cause for the formation of atherosclerotic plaques in blood vessels leading to fatality. Therefore, blocking the function of CETP has emerged as a novel strategy for suppressing atherosclerotic plaques.
View Article and Find Full Text PDF