64 results match your criteria: "Sichuan University West China Second University Hospital[Affiliation]"
BMJ Open
October 2023
Department of Nursing, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China
Objectives: The objective was to assess the prevalence of perinatal depressive symptoms and determine the trajectories of marital adjustment and depressive symptoms and their reciprocal relationships among Chinese perinatal women.
Design: This was a prospective, longitudinal cross-lagged study.
Setting: The study was conducted at the outpatient department of the largest women's and children's hospital in China, which is located in Chengdu, Sichuan Province.
Int J Gynecol Cancer
December 2023
Department of Gynecologic Oncology, Sichuan University West China Second University Hospital, Chengdu, China.
Chin J Integr Med
November 2023
National Clinical Research Center for Obstetric & Gynecologic Diseases, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Address: Peking Union Medical College Hospital (East), Beijing, 100730, China.
Objective: To evaluate the effectiveness and safety of Zhenqi Buxue Oral Liquid (ZQ), progesterone capsules, and their combination in treating oligomenorrhea and hypomenorrhea with qi-blood and Kidney (Shen) essence deficiency.
Methods: This was a prospective, randomized, multi-center controlled trial between June 2022 to December 2022. Ninety-six oligomenorrhea and hypomenorrhea patients with qi-blood and Shen essence deficiency were randomly assigned to receive ZQ (ZQ group, 29 cases), progesterone capsules (PG group, 32 cases), or the combined Chinese and Western medicine (COM group, 31 cases) at a ratio of 1:1:1.
Front Pediatr
July 2023
Department of Child Health Care, West China Women's and Children's Hospital: Sichuan University West China Second University Hospital, Chengdu, China.
Aim: To understand the prevalence of feeding difficulties (FD) in young children at self-feeding transition stage (6-24 months age), and the protective and risk predictors associated with FD are to be determined through this study.
Methods: A cross-sectional study was conducted within 5 representative Women's and Children's hospitals in Chengdu, Southwest China. Children age 6-24 months who underwent routine child health care examination at outpatient and their parents were enrolled, while the Montreal Children's Hospital Feeding Scale which is validated was used to determine whether these children have FD.
BMJ Open
April 2023
West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, China
Objective: This study aimed to examine the clinical capability of township healthcare centres (THCs), the main primary care providers in rural China, as a basis for rural health service planning.
Design: Observational study of quantitative analysis using administrative data.
Setting: Three counties with low, middle and high social economic development level, respectively, in Sichuan province western China.
Am J Obstet Gynecol MFM
August 2023
Department of Obstetrics and Gynecology, Sichuan University West China Second University Hospital, Chengdu, China (Zhan, Xu, Chen, Deng, Kong, Li and Wang); Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China (Zhan, Xu, Chen, Deng, Kong, Li and Wang). Electronic address:
Objective: Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes. Fetal cardiac dysfunction may be 1 part of the pathophysiology of pregnancies complicated by intrahepatic cholestasis of pregnancy. This systematic review and meta-analysis aimed to evaluate the association between intrahepatic cholestasis of pregnancy and fetal cardiac dysfunction.
View Article and Find Full Text PDFBMJ Open
March 2023
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Introduction: COVID-19 infections have become a global public health emergency. Although COVID-19 is primarily a respiratory disease, some of hospitalised patients exhibit cognitive impairment-related neurological damage. Using a systematic review and meta-analysis, we aim to investigate the risk factors for cognitive impairment in patients with COVID-19.
View Article and Find Full Text PDFClin Chem Lab Med
June 2023
Department of Laboratory Medicine, Sichuan University West China Second University Hospital, Chengdu, P.R. China.
Klin Padiatr
November 2022
Department of Pediatrics, Sichuan University West China Second University Hospital, Chengdu, China.
Congenital amegakaryocytic thrombocytopenia (CAMT) is an autosomal recessive disorder characterized by severe thrombocytopenia that presents soon after birth and is usually not accompanied by specific somatic malformations [Germeshausen M, Ballmaier M. Best Pract Res Clin Haematol 2021; 34: 101286]. CAMT is more prevalent in females than males [Ballmaier M, Germeshausen M.
View Article and Find Full Text PDFBMJ Open
July 2022
Centre for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China
Introduction: Morphological evaluation is used to select embryos for in vitro fertilisation. However, it does not fully reflect the implantation potential. Preimplantation genetic testing for aneuploidies (PGT-A) can detect embryonic aneuploidy, but biopsy procedure is invasive.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
June 2022
Department of Nursing, West China Second University Hospital, Sichuan University, China; Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, No. 20 Third Section, Renmin South Road, Chengdu, Sichuan Province, 610041, China. Electronic address:
Background And Objectives: It has been reported that chorioamnionitis (CA) could increase the risk of hearing impairment in premature infants, but results are inconsistent. A meta-analysis was performed to systematically evaluate the relationship between CA and hearing impairment in premature infants.
Material And Methods: Search in PubMed, Embase, Cochrane Library from their inception to May 2020.
BMJ Open
March 2022
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Introduction: COVID-19 infections have become an urgent worldwide public health concern. Although it is primarily a respiratory disease, up to two-thirds of hospitalised COVID-19 patients exhibit nervous system damage and an increased risk of frailty. In this study,we aim to investigate the relationship between frailty and cognitive function disorders in patients with COVID-19 with a systematic review and meta-analysis approach.
View Article and Find Full Text PDFBMJ Open
February 2022
Department of Gastrointestinal Surgery, Sichuan University West China Hospital, Chengdu, Sichuan, China
Introduction: Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the digestive system, and complete resection is the only way to provide a radical cure for resectable GISTs. Open surgery and minimally invasive approaches, including laparoscopy, robotic surgery and endoscopy, consist of the mainstream GIST resection. However, there is still a lack of evidence regarding which surgical outcomes and long-term prognosis would be better.
View Article and Find Full Text PDFJ Nephrol
May 2022
Division of Nephrology, Department of Medicine, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan, China.
Background And Aims: Hemophagocytic lymphohistiocytosis is a clinical syndrome caused by a cytokine storm and phagocytosis of blood cells. Acute kidney injury is typically associated with a poor prognosis in hemophagocytic lymphohistiocytosis. In the present study, a retrospective analysis of patient data was performed to identify risk factors associated with acute kidney injury in hemophagocytic lymphohistiocytosis.
View Article and Find Full Text PDFPLoS One
February 2022
Nursing Research Center, University of Electronic Science and Technology of China Sichuan Provincial People's Hospital, Chengdu, Sichuan, PR China.
Background: Pregnancy-related low back pain (PLBP) affects the daily living activities of pregnant women, even leading to fetal agitation and threatened abortion. Kinesio taping (KT) can improve the circulation of blood and provide elastic supports, which is a reliable method to treat low back pain. At present, although many studies have been published on the effects of KT on PLBP, the results are inconsistent, and some studies even report that KT does not affect PLBP.
View Article and Find Full Text PDFBMJ Open
January 2022
Department of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of Ministry of Education, Sichuan University West China Second University Hospital, Chengdu, China
Objective: This meta-analysis assessed the associations of myocardial fibrosis detected by late gadolinium-enhanced (LGE)-MRI with the risk of major adverse cardiac and cerebrovascular events (MACCEs) and major adverse cardiac events (MACEs) in patients with diabetes.
Design: Systematic review and meta-analysis reported in accordance with the guidelines of the Meta-analysis of Observational Studies in Epidemiology statement.
Data Sources: We searched the Medline, Embase and Cochrane by Ovid databases for studies published up to 27 August 2021.
J Transl Med
January 2022
Department of Gynecology, Sichuan University West China Second University Hospital, Chengdu, China.
Background: The status of vaginal microbiota in persistent high-risk human papilloma virus (HR-HPV) infection is unclear. The present work aimed to identify the vaginal microbiota of persistent HPV infection and explore the possible underlying microbiota factors.
Methods: A total of 100 women were recruited in this study, of which 28 presented HR-HPV persistent infection (P group), 30 showed clearance of any subtype of HR-HPV (C group), and 42 had no history of any HR-HPV infection (NC group).
BMJ Open
December 2021
Department of Gastrointestinal Surgery, Sichuan University West China Hospital, Chengdu, China
Introduction: Phase I/II clinical trials suggested that the hepatocyte growth factor (HGF)/mesenchymal-epithelial transition (MET) pathway-targeted agents were active in suppression of gastric cancer (GC). Randomised controlled trials (RCTs) were undertaken assessing whether the addition of anti-HGF/MET agent (rilotumumab or onartuzumab) to chemotherapy improves survival outcomes of advanced GC, but conflict conclusions were reached. Therefore, we plan to perform this systematic review and meta-analysis to synthesise evidence concerning efficacy and safety of anti-HGF/MET agents combined with chemotherapy as the first-line treatment to advanced GC.
View Article and Find Full Text PDFInt J Artif Organs
April 2022
Chinese PLA General Hospital, Beijing, China.
Introduction: Patients' session-to-session variation has been shown to influence outcomes, making critical the monitoring of dialysis dose in each session. The aim of this study was to detect the intra-patient variability of blood single pool Kt/V as measured from pre-post dialysis blood urea and from the online tool Adimea, which measures the ultraviolet absorbance of spent dialyzate.
Methods: This open, one-armed, prospective non-interventional study, evaluates patients on bicarbonate hemodialysis or/and on hemodiafiltration.
Med Ultrason
August 2022
Ultrasound Department, Sichuan University West China Second University Hospital/Key Laboratory of Obstetrics & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Chengdu, Si Chuan Province, 610041, China.
Aim: Transvaginal ultrasonography (TVUS) has shown varying results in the staging of cervical cancer patients around the world. Hence, the current review was done to assess the diagnostic accuracy of TVUS for identifying parametrial, stromal invasion and lymph node metastasis among cervical cancer patients.
Material And Methods: We conducted a systematic search for all studies reporting the diagnostic accuracy of TVUS for staging of cervical cancer in the databases of PubMed Central, MEDLINE, EMBASE, MEDLINE, SCOPUS and Cochrane library from inception till March 2021.
BMJ Open
September 2021
Department of Obstetrics, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China
Objectives: This study aims to use the high-quality national monitoring data from the China's National Maternal Near Miss Surveillance System (NMNMSS) to ascertain the incidence, trends and risk factors of obstetric massive blood transfusion (MBT) from 2012 to 2019 in China and determine its clinical outcomes.
Settings: Observational study of hospitalised pregnancies who had given birth or ended their pregnancy among member hospitals of NMNMSS.
Participants: 11 667 406 women were included in this study.
BMJ Open
May 2021
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA.
Aims: To evaluate the type 2 diabetes mellitus (T2DM) risk of individuals with different types of dyslipidaemia and compare the predictive value of distinct lipid parameters in predicting T2DM.
Methods: We conducted a secondary analysis of data from the China Health and Retirement Longitudinal Study (CHARLS). 17 708 individuals over 45 years old were interviewed, and 11 847 blood samples were collected at the baseline survey (2011-2012).
Front Pediatr
March 2021
Department of Biostatistics, Peking University First Hospital, Beijing, China.
Targeted urinalysis has been suggested to improve screening efficiency in adults. However, there is no well-defined target population in children yet, with limited information on the risk factors for urinalysis abnormalities. Children from infants to 17 years old were randomly selected.
View Article and Find Full Text PDFBMJ Open
April 2021
West China School of Nursing, West China Hospital, Sichuan University, Chengdu, China
Aim: The aim of this study was to adapt the Chinese version of Hospital Nursing Department Disaster Preparedness Scale (HNDDPS) and evaluate the psychometric properties among hospital nurses in China. Two specific objectives were (1) to adapt the HNDDPS from Sadiq's Organisational Disaster Preparedness Scale (SODPS) to fit the context of Chinese hospital nursing system and (2) to establish its validity and reliability.
Design: Instrument design study.
Ann Rheum Dis
May 2023
Reproductive Medical Center, Department of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Sichuan University West China Second University Hospital, Chengdu, Sichuan, China